Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2387
  Reference Plasmid   1111525849768046_bin.37__k141_155460
  Reference Plasmid Size   2639
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0120889 MIMBKINH_00001 48 4 Oral 1.00 protein_coding synonymous_variant LOW 42T>A Pro14Pro
M0120890 MIMBKINH_00001 99 3 Oral 0.75 protein_coding synonymous_variant LOW 93T>A Ala31Ala
M0120891 MIMBKINH_00001 198 3 Oral 0.75 protein_coding synonymous_variant LOW 192C>A Val64Val
M0120892 MIMBKINH_00001 228 3 Oral 0.75 protein_coding synonymous_variant LOW 222A>G Leu74Leu
M0120893 MIMBKINH_00001 384 3 Oral 0.75 protein_coding synonymous_variant LOW 378T>C Tyr126Tyr
M0120894 MIMBKINH_00001 939 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *540G>A None
M0120895 MIMBKINH_00001 978 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *579T>C None
M0120896 MIMBKINH_00001 996 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *597C>T None
M0120897 MIMBKINH_00001 1174 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *775C>T None
M0120898 MIMBKINH_00001 1335 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *936A>G None
M0120899 MIMBKINH_00001 1344 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *945T>C None
M0120900 MIMBKINH_00001 1410 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1011C>T None
M0120901 MIMBKINH_00001 1413 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1014T>A None
M0120902 MIMBKINH_00001 1480 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1081T>C None
M0120903 MIMBKINH_00001 1530 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *1131C>T None
M0120904 MIMBKINH_00001 1656 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1257T>C None
M0120905 MIMBKINH_00001 1752 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1353A>C None
M0120906 MIMBKINH_00001 2094 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1695A>G None
M0120907 MIMBKINH_00001 2157 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1758T>C None
M0120908 MIMBKINH_00001 2187 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1788C>T None
M0120909 MIMBKINH_00001 2205 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *1806C>A None
M0120910 MIMBKINH_00001 2247 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1848C>T None
M0120911 MIMBKINH_00001 2337 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1938T>C None
M0120912 MIMBKINH_00001 2373 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *1974G>A None
M0120913 MIMBKINH_00001 2382 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *1983C>A None
M0120914 MIMBKINH_00001 2400 4 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *2001C>T None
M0120915 MIMBKINH_00001 2271 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *1872C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term