Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2390
  Reference Plasmid   1111525849768046_bin.37__k141_158985
  Reference Plasmid Size   4319
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0121224 ACKPHBIN_00003 2988 5 Oral 0.83 protein_coding synonymous_variant LOW 1098T>A Ile366Ile
M0121225 ACKPHBIN_00003 2994 4 Oral 0.67 protein_coding missense_variant MODERATE 1092G>A Met364Ile
M0121226 ACKPHBIN_00003 2995 4 Oral 0.67 protein_coding missense_variant MODERATE 1091T>C Met364Thr
M0121227 ACKPHBIN_00003 3066 3 Oral 0.50 protein_coding synonymous_variant LOW 1020A>G Thr340Thr
M0121228 ACKPHBIN_00003 3071 4 Oral 0.67 protein_coding missense_variant MODERATE 1015T>A Ser339Thr
M0121229 ACKPHBIN_00003 3123 4 Oral 0.67 protein_coding synonymous_variant LOW 963C>T Asp321Asp
M0121230 ACKPHBIN_00003 3126 4 Oral 0.67 protein_coding synonymous_variant LOW 960T>C Ile320Ile
M0121231 ACKPHBIN_00003 3182 4 Oral 0.67 protein_coding missense_variant MODERATE 904T>G Ser302Ala
M0121232 ACKPHBIN_00003 3204 4 Oral 0.67 protein_coding synonymous_variant LOW 882A>C Thr294Thr
M0121233 ACKPHBIN_00003 3213 4 Oral 0.67 protein_coding synonymous_variant LOW 873C>T Leu291Leu
M0121234 ACKPHBIN_00003 3303 3 Oral 0.50 protein_coding synonymous_variant LOW 783T>C Ala261Ala
M0121235 ACKPHBIN_00003 3306 3 Oral 0.50 protein_coding synonymous_variant LOW 780G>A Val260Val
M0121236 ACKPHBIN_00003 3330 3 Oral 0.50 protein_coding synonymous_variant LOW 756A>G Val252Val
M0121237 ACKPHBIN_00003 3350 3 Oral 0.50 protein_coding missense_variant MODERATE 736A>G Ile246Val
M0121238 ACKPHBIN_00003 3660 4 Oral 0.67 protein_coding synonymous_variant LOW 426C>T Leu142Leu
M0121239 ACKPHBIN_00003 3933 3 Oral 0.50 protein_coding synonymous_variant LOW 153T>C Cys51Cys
M0121240 ACKPHBIN_00003 3970 3 Oral 0.50 protein_coding missense_variant MODERATE 116T>C Met39Thr
M0121241 ACKPHBIN_00002 1131 3 Oral 0.50 protein_coding missense_variant MODERATE 1664A>G Asn555Ser
M0121242 ACKPHBIN_00002 1433 3 Oral 0.50 protein_coding synonymous_variant LOW 1362T>C His454His
M0121243 ACKPHBIN_00002 1655 3 Oral 0.50 protein_coding synonymous_variant LOW 1140A>G Val380Val
M0121244 ACKPHBIN_00002 1760 3 Oral 0.50 protein_coding synonymous_variant LOW 1035A>T Val345Val
M0121245 ACKPHBIN_00002 2222 4 Oral 0.67 protein_coding synonymous_variant LOW 573T>C His191His
M0121246 ACKPHBIN_00002 2246 4 Oral 0.67 protein_coding synonymous_variant LOW 549A>G Glu183Glu
M0121247 ACKPHBIN_00002 2444 4 Oral 0.67 protein_coding synonymous_variant LOW 351C>T Asp117Asp
M0121248 ACKPHBIN_00002 2519 3 Oral 0.50 protein_coding synonymous_variant LOW 276C>T Tyr92Tyr
M0121249 ACKPHBIN_00002 2534 3 Oral 0.50 protein_coding synonymous_variant LOW 261C>T Asp87Asp
M0121250 ACKPHBIN_00002 2600 5 Oral 0.83 protein_coding synonymous_variant LOW 195C>T Gly65Gly
M0121251 ACKPHBIN_00002 1991 3 Oral 0.50 protein_coding synonymous_variant LOW 804T>C Asp268Asp
M0121252 ACKPHBIN_00002 2006 3 Oral 0.50 protein_coding synonymous_variant LOW 789C>T Asn263Asn
M0121253 ACKPHBIN_00002 2045 3 Oral 0.50 protein_coding synonymous_variant LOW 750C>T Ser250Ser
M0121254 ACKPHBIN_00002 2237 3 Oral 0.50 protein_coding synonymous_variant LOW 558C>T Asn186Asn
M0121255 ACKPHBIN_00003 3411 3 Oral 0.50 protein_coding synonymous_variant LOW 675C>T Asn225Asn
M0121256 ACKPHBIN_00003 3423 3 Oral 0.50 protein_coding synonymous_variant LOW 663T>C Ile221Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term