Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2391
  Reference Plasmid   1111525849768046_bin.37__k141_161321
  Reference Plasmid Size   4039
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0121257 FGPLIHKL_00001 512 7 Oral 0.70 protein_coding synonymous_variant LOW 405C>T Leu135Leu
M0121258 FGPLIHKL_00001 524 6 Oral 0.60 protein_coding missense_variant MODERATE 393A>G Ile131Met
M0121259 FGPLIHKL_00001 551 4 Oral 0.40 protein_coding synonymous_variant LOW 366A>G Gly122Gly
M0121260 FGPLIHKL_00001 554 4 Oral 0.40 protein_coding synonymous_variant LOW 363C>T Gly121Gly
M0121261 FGPLIHKL_00001 584 7 Oral 0.70 protein_coding synonymous_variant LOW 333C>T Ser111Ser
M0121262 FGPLIHKL_00001 961 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -45A>G None
M0121263 FGPLIHKL_00002 1118 4 Oral 0.40 protein_coding synonymous_variant LOW 411T>C Arg137Arg
M0121264 FGPLIHKL_00002 1157 4 Oral 0.40 protein_coding synonymous_variant LOW 372T>A Thr124Thr
M0121265 FGPLIHKL_00001 1536 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -620T>C None
M0121266 FGPLIHKL_00003 1811 5 Oral 0.50 protein_coding synonymous_variant LOW 114T>C Asp38Asp
M0121267 FGPLIHKL_00003 2639 7 Oral 0.70 protein_coding synonymous_variant LOW 942A>T Ala314Ala
M0121268 FGPLIHKL_00003 2741 6 Oral 0.60 protein_coding synonymous_variant LOW 1044A>G Ser348Ser
M0121269 FGPLIHKL_00003 2994 8 Oral 0.80 protein_coding synonymous_variant LOW 1297T>C Leu433Leu
M0121270 FGPLIHKL_00003 3017 6 Oral 0.60 protein_coding synonymous_variant LOW 1320A>G Glu440Glu
M0121271 FGPLIHKL_00003 3176 6 Oral 0.60 protein_coding synonymous_variant LOW 1479A>T Ala493Ala
M0121272 FGPLIHKL_00003 3239 8 Oral 0.80 protein_coding synonymous_variant LOW 1542T>C Gly514Gly
M0121273 FGPLIHKL_00001 3465 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -2549T>C None
M0121274 FGPLIHKL_00001 3466 6 Oral 0.60 protein_coding upstream_gene_variant MODIFIER -2550C>T None
M0121275 FGPLIHKL_00001 3474 8 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -2558G>C None
M0121276 FGPLIHKL_00001 3478 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2562T>C None
M0121277 FGPLIHKL_00001 3514 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -2598G>T None
M0121278 FGPLIHKL_00001 3515 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -2599T>C None
M0121279 FGPLIHKL_00001 3545 7 Oral 0.70 protein_coding upstream_gene_variant MODIFIER -2629G>A None
M0121280 FGPLIHKL_00001 3580 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2664T>A None
M0121281 FGPLIHKL_00001 3872 9 Oral 0.90 protein_coding upstream_gene_variant MODIFIER -2956C>T None
M0121282 FGPLIHKL_00001 4006 8 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -3090T>C None
M0121283 FGPLIHKL_00001 4012 7 Oral 0.70 protein_coding upstream_gene_variant MODIFIER -3096A>G None
M0121284 FGPLIHKL_00001 530 3 Oral 0.30 protein_coding synonymous_variant LOW 387T>A Leu129Leu
M0121285 FGPLIHKL_00001 563 3 Oral 0.30 protein_coding synonymous_variant LOW 354C>T Tyr118Tyr
M0121286 FGPLIHKL_00001 605 4 Oral 0.40 protein_coding synonymous_variant LOW 312A>T Pro104Pro
M0121287 FGPLIHKL_00001 611 4 Oral 0.40 protein_coding synonymous_variant LOW 306T>C Asn102Asn
M0121288 FGPLIHKL_00001 620 4 Oral 0.40 protein_coding synonymous_variant LOW 297C>T Ile99Ile
M0121289 FGPLIHKL_00001 653 4 Oral 0.40 protein_coding synonymous_variant LOW 264A>G Glu88Glu
M0121290 FGPLIHKL_00001 665 4 Oral 0.40 protein_coding synonymous_variant LOW 252C>A Thr84Thr
M0121291 FGPLIHKL_00001 701 4 Oral 0.40 protein_coding synonymous_variant LOW 216T>C Tyr72Tyr
M0121292 FGPLIHKL_00001 3964 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -3048A>T None
M0121293 FGPLIHKL_00001 3994 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -3078G>A None
M0121294 FGPLIHKL_00001 3997 5 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -3081C>T None
M0121295 FGPLIHKL_00001 659 3 Oral 0.30 protein_coding missense_variant MODERATE 258A>G Ile86Met
M0121296 FGPLIHKL_00001 851 3 Oral 0.30 protein_coding synonymous_variant LOW 66G>A Ala22Ala
M0121297 FGPLIHKL_00001 964 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -48T>C None
M0121298 FGPLIHKL_00001 965 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -49G>A None
M0121299 FGPLIHKL_00001 973 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -57C>T None
M0121300 FGPLIHKL_00001 1060 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -144A>C None
M0121301 FGPLIHKL_00002 1451 3 Oral 0.30 protein_coding synonymous_variant LOW 78G>A Leu26Leu
M0121302 FGPLIHKL_00001 1560 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -644G>A None
M0121303 FGPLIHKL_00001 1561 4 Oral 0.40 protein_coding upstream_gene_variant MODIFIER -645A>G None
M0121304 FGPLIHKL_00003 2039 3 Oral 0.30 protein_coding synonymous_variant LOW 342T>C Asp114Asp
M0121305 FGPLIHKL_00003 2057 3 Oral 0.30 protein_coding synonymous_variant LOW 360C>T Asp120Asp
M0121306 FGPLIHKL_00003 2177 3 Oral 0.30 protein_coding synonymous_variant LOW 480C>T Ile160Ile
M0121307 FGPLIHKL_00003 2183 3 Oral 0.30 protein_coding synonymous_variant LOW 486A>G Val162Val
M0121308 FGPLIHKL_00003 2282 3 Oral 0.30 protein_coding synonymous_variant LOW 585T>C Ser195Ser
M0121309 FGPLIHKL_00003 2345 5 Oral 0.50 protein_coding synonymous_variant LOW 648A>G Lys216Lys
M0121310 FGPLIHKL_00003 2465 3 Oral 0.30 protein_coding synonymous_variant LOW 768C>T His256His
M0121311 FGPLIHKL_00003 2486 5 Oral 0.50 protein_coding synonymous_variant LOW 789C>T Asn263Asn
M0121312 FGPLIHKL_00003 2635 6 Oral 0.60 protein_coding missense_variant MODERATE 938A>G Asn313Ser
M0121313 FGPLIHKL_00003 2675 3 Oral 0.30 protein_coding synonymous_variant LOW 978G>A Ser326Ser
M0121314 FGPLIHKL_00003 2783 3 Oral 0.30 protein_coding synonymous_variant LOW 1086G>A Lys362Lys
M0121315 FGPLIHKL_00003 2933 3 Oral 0.30 protein_coding synonymous_variant LOW 1236T>C Ala412Ala
M0121316 FGPLIHKL_00003 2942 3 Oral 0.30 protein_coding synonymous_variant LOW 1245T>A Leu415Leu
M0121317 FGPLIHKL_00003 2960 4 Oral 0.40 protein_coding synonymous_variant LOW 1263C>T Asn421Asn
M0121318 FGPLIHKL_00003 3086 4 Oral 0.40 protein_coding synonymous_variant LOW 1389G>A Glu463Glu
M0121319 FGPLIHKL_00003 3097 4 Oral 0.40 protein_coding missense_variant MODERATE 1400G>A Arg467Gln
M0121320 FGPLIHKL_00003 3143 5 Oral 0.50 protein_coding synonymous_variant LOW 1446A>T Val482Val
M0121321 FGPLIHKL_00001 3480 3 Oral 0.30 protein_coding upstream_gene_variant MODIFIER -2564T>C None
M0121322 FGPLIHKL_00004 3600 5 Oral 0.50 protein_coding synonymous_variant LOW 9A>G Glu3Glu
M0121323 FGPLIHKL_00004 3615 3 Oral 0.30 protein_coding synonymous_variant LOW 24G>A Lys8Lys
M0121324 FGPLIHKL_00004 3631 3 Oral 0.30 protein_coding missense_variant MODERATE 40G>A Ala14Thr
M0121325 FGPLIHKL_00004 3632 3 Oral 0.30 protein_coding missense_variant MODERATE 41C>A Ala14Glu
M0121326 FGPLIHKL_00003 2360 3 Oral 0.30 protein_coding synonymous_variant LOW 663G>A Glu221Glu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term