Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2401
  Reference Plasmid   1111525849768046_bin.37__k141_179950
  Reference Plasmid Size   4309
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0122476 CEHKLHAE_00002 1314 6 Oral 1.00 protein_coding synonymous_variant LOW 2922C>T Leu974Leu
M0122477 CEHKLHAE_00002 1347 3 Oral 0.50 protein_coding synonymous_variant LOW 2889A>C Leu963Leu
M0122478 CEHKLHAE_00002 1365 3 Oral 0.50 protein_coding synonymous_variant LOW 2871T>C Val957Val
M0122479 CEHKLHAE_00002 1425 5 Oral 0.83 protein_coding synonymous_variant LOW 2811G>A Lys937Lys
M0122480 CEHKLHAE_00002 1443 5 Oral 0.83 protein_coding synonymous_variant LOW 2793T>C Asp931Asp
M0122481 CEHKLHAE_00002 1464 5 Oral 0.83 protein_coding synonymous_variant LOW 2772A>G Leu924Leu
M0122482 CEHKLHAE_00002 1638 3 Oral 0.50 protein_coding synonymous_variant LOW 2598A>T Thr866Thr
M0122483 CEHKLHAE_00002 1764 5 Oral 0.83 protein_coding synonymous_variant LOW 2472T>C Gly824Gly
M0122484 CEHKLHAE_00002 1797 5 Oral 0.83 protein_coding synonymous_variant LOW 2439A>G Glu813Glu
M0122485 CEHKLHAE_00002 1803 4 Oral 0.67 protein_coding synonymous_variant LOW 2433G>A Arg811Arg
M0122486 CEHKLHAE_00002 1809 4 Oral 0.67 protein_coding synonymous_variant LOW 2427A>G Arg809Arg
M0122487 CEHKLHAE_00002 1830 5 Oral 0.83 protein_coding synonymous_variant LOW 2406T>C Ser802Ser
M0122488 CEHKLHAE_00002 1854 5 Oral 0.83 protein_coding synonymous_variant LOW 2382C>T Cys794Cys
M0122489 CEHKLHAE_00002 1905 5 Oral 0.83 protein_coding synonymous_variant LOW 2331T>C Asp777Asp
M0122490 CEHKLHAE_00002 1983 3 Oral 0.50 protein_coding synonymous_variant LOW 2253C>T Thr751Thr
M0122491 CEHKLHAE_00002 2031 3 Oral 0.50 protein_coding synonymous_variant LOW 2205A>C Ile735Ile
M0122492 CEHKLHAE_00002 2052 4 Oral 0.67 protein_coding synonymous_variant LOW 2184A>G Gln728Gln
M0122493 CEHKLHAE_00002 2117 4 Oral 0.67 protein_coding synonymous_variant LOW 2119C>T Leu707Leu
M0122494 CEHKLHAE_00002 2226 3 Oral 0.50 protein_coding synonymous_variant LOW 2010G>C Thr670Thr
M0122495 CEHKLHAE_00002 2268 3 Oral 0.50 protein_coding synonymous_variant LOW 1968T>C Ser656Ser
M0122496 CEHKLHAE_00002 2337 3 Oral 0.50 protein_coding synonymous_variant LOW 1899G>A Thr633Thr
M0122497 CEHKLHAE_00002 2355 5 Oral 0.83 protein_coding missense_variant MODERATE 1881G>T Met627Ile
M0122498 CEHKLHAE_00002 2388 3 Oral 0.50 protein_coding synonymous_variant LOW 1848C>T Phe616Phe
M0122499 CEHKLHAE_00002 2586 5 Oral 0.83 protein_coding synonymous_variant LOW 1650T>C Ser550Ser
M0122500 CEHKLHAE_00002 2646 4 Oral 0.67 protein_coding synonymous_variant LOW 1590C>T Asp530Asp
M0122501 CEHKLHAE_00002 2775 4 Oral 0.67 protein_coding synonymous_variant LOW 1461G>A Gln487Gln
M0122502 CEHKLHAE_00002 2883 5 Oral 0.83 protein_coding synonymous_variant LOW 1353T>A Ile451Ile
M0122503 CEHKLHAE_00002 2937 5 Oral 0.83 protein_coding synonymous_variant LOW 1299G>A Glu433Glu
M0122504 CEHKLHAE_00002 3111 5 Oral 0.83 protein_coding synonymous_variant LOW 1125A>T Gly375Gly
M0122505 CEHKLHAE_00002 3168 4 Oral 0.67 protein_coding synonymous_variant LOW 1068A>G Gln356Gln
M0122506 CEHKLHAE_00002 3222 3 Oral 0.50 protein_coding synonymous_variant LOW 1014G>A Leu338Leu
M0122507 CEHKLHAE_00002 3353 5 Oral 0.83 protein_coding missense_variant MODERATE 883A>G Met295Val
M0122508 CEHKLHAE_00002 3354 3 Oral 0.50 protein_coding synonymous_variant LOW 882G>A Lys294Lys
M0122509 CEHKLHAE_00002 3360 4 Oral 0.67 protein_coding synonymous_variant LOW 876T>G Ala292Ala
M0122510 CEHKLHAE_00002 3540 3 Oral 0.50 protein_coding synonymous_variant LOW 696T>C Ala232Ala
M0122511 CEHKLHAE_00002 3573 3 Oral 0.50 protein_coding synonymous_variant LOW 663A>G Glu221Glu
M0122512 CEHKLHAE_00002 3627 3 Oral 0.50 protein_coding synonymous_variant LOW 609T>A Ile203Ile
M0122513 CEHKLHAE_00002 4230 5 Oral 0.83 protein_coding synonymous_variant LOW 6G>A Arg2Arg
M0122514 CEHKLHAE_00001 146 3 Oral 0.50 protein_coding synonymous_variant LOW 30A>T Ile10Ile
M0122515 CEHKLHAE_00001 191 4 Oral 0.67 protein_coding synonymous_variant LOW 75A>T Ser25Ser
M0122516 CEHKLHAE_00001 200 4 Oral 0.67 protein_coding synonymous_variant LOW 84A>T Ala28Ala
M0122517 CEHKLHAE_00001 248 3 Oral 0.50 protein_coding synonymous_variant LOW 132A>T Gly44Gly
M0122518 CEHKLHAE_00001 269 4 Oral 0.67 protein_coding synonymous_variant LOW 153C>T Ile51Ile
M0122519 CEHKLHAE_00001 281 4 Oral 0.67 protein_coding synonymous_variant LOW 165A>C Thr55Thr
M0122520 CEHKLHAE_00001 323 4 Oral 0.67 protein_coding synonymous_variant LOW 207T>C Asn69Asn
M0122521 CEHKLHAE_00001 356 3 Oral 0.50 protein_coding synonymous_variant LOW 240G>A Leu80Leu
M0122522 CEHKLHAE_00001 401 3 Oral 0.50 protein_coding synonymous_variant LOW 285G>A Lys95Lys
M0122523 CEHKLHAE_00001 662 5 Oral 0.83 protein_coding synonymous_variant LOW 546A>G Thr182Thr
M0122524 CEHKLHAE_00001 827 4 Oral 0.67 protein_coding synonymous_variant LOW 711A>G Lys237Lys
M0122525 CEHKLHAE_00001 876 3 Oral 0.50 protein_coding synonymous_variant LOW 760T>C Leu254Leu
M0122526 CEHKLHAE_00001 881 3 Oral 0.50 protein_coding synonymous_variant LOW 765T>C Ile255Ile
M0122527 CEHKLHAE_00001 986 4 Oral 0.67 protein_coding missense_variant MODERATE 870G>T Leu290Phe
M0122528 CEHKLHAE_00001 1030 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *41A>G None
M0122529 CEHKLHAE_00001 1102 3 Oral 0.50 protein_coding downstream_gene_variant MODIFIER *113A>G None
M0122530 CEHKLHAE_00002 1110 3 Oral 0.50 protein_coding synonymous_variant LOW 3126G>A Lys1042Lys
M0122531 CEHKLHAE_00002 1113 3 Oral 0.50 protein_coding synonymous_variant LOW 3123A>G Glu1041Glu
M0122532 CEHKLHAE_00002 1149 3 Oral 0.50 protein_coding synonymous_variant LOW 3087A>T Thr1029Thr
M0122533 CEHKLHAE_00002 1209 5 Oral 0.83 protein_coding synonymous_variant LOW 3027G>A Arg1009Arg
M0122534 CEHKLHAE_00002 1311 4 Oral 0.67 protein_coding synonymous_variant LOW 2925C>T Arg975Arg
M0122535 CEHKLHAE_00002 1320 5 Oral 0.83 protein_coding synonymous_variant LOW 2916A>C Ile972Ile
M0122536 CEHKLHAE_00002 1641 3 Oral 0.50 protein_coding synonymous_variant LOW 2595C>T Val865Val
M0122537 CEHKLHAE_00001 851 3 Oral 0.50 protein_coding synonymous_variant LOW 735A>G Leu245Leu
M0122538 CEHKLHAE_00002 1248 3 Oral 0.50 protein_coding synonymous_variant LOW 2988T>A Ala996Ala
M0122539 CEHKLHAE_00002 1569 3 Oral 0.50 protein_coding synonymous_variant LOW 2667A>G Ala889Ala
M0122540 CEHKLHAE_00002 1980 4 Oral 0.67 protein_coding synonymous_variant LOW 2256C>T Ile752Ile
M0122541 CEHKLHAE_00002 1997 4 Oral 0.67 protein_coding synonymous_variant LOW 2239C>T Leu747Leu
M0122542 CEHKLHAE_00002 2199 3 Oral 0.50 protein_coding synonymous_variant LOW 2037G>T Val679Val
M0122543 CEHKLHAE_00002 2709 3 Oral 0.50 protein_coding synonymous_variant LOW 1527T>C Cys509Cys
M0122544 CEHKLHAE_00002 2718 3 Oral 0.50 protein_coding synonymous_variant LOW 1518G>A Arg506Arg
M0122545 CEHKLHAE_00002 2720 3 Oral 0.50 protein_coding synonymous_variant LOW 1516A>C Arg506Arg
M0122546 CEHKLHAE_00002 2727 3 Oral 0.50 protein_coding synonymous_variant LOW 1509T>C Pro503Pro
M0122547 CEHKLHAE_00002 2904 4 Oral 0.67 protein_coding synonymous_variant LOW 1332A>G Lys444Lys
M0122548 CEHKLHAE_00002 4005 3 Oral 0.50 protein_coding synonymous_variant LOW 231G>A Glu77Glu
M0122549 CEHKLHAE_00002 4053 3 Oral 0.50 protein_coding synonymous_variant LOW 183T>C Arg61Arg
M0122550 CEHKLHAE_00001 773 3 Oral 0.50 protein_coding synonymous_variant LOW 657G>A Ala219Ala
M0122551 CEHKLHAE_00002 2484 3 Oral 0.50 protein_coding synonymous_variant LOW 1752T>C Gly584Gly
M0122552 CEHKLHAE_00002 3114 3 Oral 0.50 protein_coding synonymous_variant LOW 1122T>C Phe374Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term