Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C2409 |
Reference Plasmid |
1111525849768046_bin.37__k141_188781 |
Reference Plasmid Size |
13883 |
Reference Plasmid GC Content |
0.38 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0122998 |
GKOOPNEP_00006 |
7035 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
234T>C |
Val78Val |
M0122999 |
GKOOPNEP_00006 |
7065 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
264G>T |
Leu88Phe |
M0123000 |
GKOOPNEP_00006 |
7131 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
330T>C |
Cys110Cys |
M0123001 |
GKOOPNEP_00006 |
7144 |
8 |
Oral |
0.53 |
protein_coding |
missense_variant |
MODERATE |
343T>G |
Tyr115Asp |
M0123002 |
GKOOPNEP_00006 |
7285 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
484A>G |
Ile162Val |
M0123003 |
GKOOPNEP_00006 |
7344 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
543C>T |
Phe181Phe |
M0123004 |
GKOOPNEP_00006 |
7395 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
594A>C |
Arg198Ser |
M0123005 |
GKOOPNEP_00006 |
7405 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
604A>G |
Lys202Glu |
M0123006 |
GKOOPNEP_00006 |
7406 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
605A>C |
Lys202Thr |
M0123007 |
GKOOPNEP_00006 |
7521 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
720A>T |
Val240Val |
M0123008 |
GKOOPNEP_00006 |
7783 |
6 |
Oral |
0.40 |
protein_coding |
missense_variant |
MODERATE |
982A>C |
Thr328Pro |
M0123009 |
GKOOPNEP_00006 |
7839 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1038T>C |
Gly346Gly |
M0123010 |
GKOOPNEP_00006 |
7851 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1050A>G |
Leu350Leu |
M0123011 |
GKOOPNEP_00006 |
7893 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
1092T>C |
Phe364Phe |
M0123012 |
GKOOPNEP_00006 |
7998 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1197T>G |
Phe399Leu |
M0123013 |
GKOOPNEP_00006 |
8010 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1209T>C |
Ile403Ile |
M0123014 |
GKOOPNEP_00006 |
8132 |
8 |
Oral |
0.53 |
protein_coding |
missense_variant |
MODERATE |
1331T>C |
Val444Ala |
M0123015 |
GKOOPNEP_00006 |
8152 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
1351T>A |
Leu451Met |
M0123016 |
GKOOPNEP_00006 |
8196 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
1395A>C |
Glu465Asp |
M0123017 |
GKOOPNEP_00006 |
8481 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
1680G>A |
Lys560Lys |
M0123018 |
GKOOPNEP_00006 |
8574 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
1773C>T |
Asn591Asn |
M0123019 |
GKOOPNEP_00006 |
8673 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1872T>A |
Ile624Ile |
M0123020 |
GKOOPNEP_00006 |
8677 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
1876T>G |
Ser626Ala |
M0123021 |
GKOOPNEP_00006 |
8709 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1908T>C |
Tyr636Tyr |
M0123022 |
GKOOPNEP_00007 |
9233 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
265T>G |
Ser89Ala |
M0123023 |
GKOOPNEP_00007 |
9313 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
345T>C |
His115His |
M0123024 |
GKOOPNEP_00007 |
9382 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
414T>C |
Thr138Thr |
M0123025 |
GKOOPNEP_00007 |
9511 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
543A>T |
Pro181Pro |
M0123026 |
GKOOPNEP_00007 |
9541 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
573G>A |
Ser191Ser |
M0123027 |
GKOOPNEP_00007 |
9661 |
9 |
Oral |
0.60 |
protein_coding |
synonymous_variant |
LOW |
693C>T |
Val231Val |
M0123028 |
GKOOPNEP_00008 |
9879 |
9 |
Oral |
0.60 |
protein_coding |
synonymous_variant |
LOW |
204G>A |
Glu68Glu |
M0123029 |
GKOOPNEP_00008 |
10044 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
369G>A |
Gln123Gln |
M0123030 |
GKOOPNEP_00003 |
10397 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4705A>G |
None |
M0123031 |
GKOOPNEP_00003 |
10399 |
8 |
Oral |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4707T>G |
None |
M0123032 |
GKOOPNEP_00003 |
10405 |
8 |
Oral |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4713T>C |
None |
M0123033 |
GKOOPNEP_00003 |
10423 |
8 |
Oral |
0.53 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4731C>T |
None |
M0123034 |
GKOOPNEP_00009 |
10531 |
8 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
54G>A |
Gly18Gly |
M0123035 |
GKOOPNEP_00009 |
10555 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
78T>C |
Leu26Leu |
M0123036 |
GKOOPNEP_00009 |
10624 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
147A>G |
Gly49Gly |
M0123037 |
GKOOPNEP_00009 |
10687 |
8 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
210G>A |
Lys70Lys |
M0123038 |
GKOOPNEP_00009 |
10778 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
301C>T |
Leu101Leu |
M0123039 |
GKOOPNEP_00009 |
10786 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
309A>T |
Thr103Thr |
M0123040 |
GKOOPNEP_00009 |
10882 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
405C>T |
Ala135Ala |
M0123041 |
GKOOPNEP_00009 |
11047 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
570T>C |
Tyr190Tyr |
M0123042 |
GKOOPNEP_00009 |
11068 |
8 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
591T>C |
Ser197Ser |
M0123043 |
GKOOPNEP_00009 |
11098 |
9 |
Oral |
0.60 |
protein_coding |
synonymous_variant |
LOW |
621A>G |
Glu207Glu |
M0123044 |
GKOOPNEP_00002 |
4109 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
135G>A |
Glu45Glu |
M0123045 |
GKOOPNEP_00002 |
4148 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
96A>C |
Glu32Asp |
M0123046 |
GKOOPNEP_00002 |
4172 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
72G>A |
Gln24Gln |
M0123047 |
GKOOPNEP_00002 |
4214 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
30T>C |
Asp10Asp |
M0123048 |
GKOOPNEP_00001 |
4256 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1268C>T |
None |
M0123049 |
GKOOPNEP_00001 |
4257 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1269A>G |
None |
M0123050 |
GKOOPNEP_00001 |
4261 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1273C>T |
None |
M0123051 |
GKOOPNEP_00003 |
4268 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
1425A>T |
Gln475His |
M0123052 |
GKOOPNEP_00003 |
4269 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
1424A>C |
Gln475Pro |
M0123053 |
GKOOPNEP_00003 |
4270 |
5 |
Oral |
0.33 |
protein_coding |
stop_gained |
HIGH |
1423C>T |
Gln475* |
M0123054 |
GKOOPNEP_00003 |
4313 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1380G>A |
Leu460Leu |
M0123055 |
GKOOPNEP_00003 |
4328 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1365T>C |
Asn455Asn |
M0123056 |
GKOOPNEP_00003 |
4565 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1128A>G |
Thr376Thr |
M0123057 |
GKOOPNEP_00003 |
4751 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
942C>T |
Ile314Ile |
M0123058 |
GKOOPNEP_00003 |
4760 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
933C>T |
His311His |
M0123059 |
GKOOPNEP_00003 |
4778 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
915C>T |
Gly305Gly |
M0123060 |
GKOOPNEP_00003 |
4883 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
810T>A |
Val270Val |
M0123061 |
GKOOPNEP_00003 |
4979 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
714G>A |
Leu238Leu |
M0123062 |
GKOOPNEP_00003 |
5003 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
690C>T |
Phe230Phe |
M0123063 |
GKOOPNEP_00003 |
5101 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
592T>C |
Leu198Leu |
M0123064 |
GKOOPNEP_00003 |
5102 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
591A>G |
Ala197Ala |
M0123065 |
GKOOPNEP_00003 |
5156 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
537T>C |
Cys179Cys |
M0123066 |
GKOOPNEP_00003 |
5159 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
534C>T |
Arg178Arg |
M0123067 |
GKOOPNEP_00003 |
5162 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
531G>A |
Leu177Leu |
M0123068 |
GKOOPNEP_00003 |
5201 |
5 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
492A>C |
Glu164Asp |
M0123069 |
GKOOPNEP_00003 |
5207 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
486T>C |
Pro162Pro |
M0123070 |
GKOOPNEP_00003 |
5417 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
276T>A |
Ile92Ile |
M0123071 |
GKOOPNEP_00003 |
5441 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
252C>T |
Thr84Thr |
M0123072 |
GKOOPNEP_00003 |
5504 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
189C>T |
Ala63Ala |
M0123073 |
GKOOPNEP_00003 |
5528 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
165A>T |
Val55Val |
M0123074 |
GKOOPNEP_00005 |
6500 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
234A>G |
Leu78Leu |
M0123075 |
GKOOPNEP_00005 |
6678 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
412C>T |
Leu138Leu |
M0123076 |
GKOOPNEP_00006 |
6960 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
159C>T |
Ser53Ser |
M0123077 |
GKOOPNEP_00006 |
6966 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
165A>G |
Leu55Leu |
M0123078 |
GKOOPNEP_00006 |
7032 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
231A>T |
Ala77Ala |
M0123079 |
GKOOPNEP_00006 |
7260 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
459C>T |
Asn153Asn |
M0123080 |
GKOOPNEP_00006 |
7267 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
466C>A |
Leu156Ile |
M0123081 |
GKOOPNEP_00006 |
7329 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
528A>G |
Leu176Leu |
M0123082 |
GKOOPNEP_00006 |
7332 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
531C>T |
Pro177Pro |
M0123083 |
GKOOPNEP_00001 |
62 |
3 |
Oral |
0.20 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1445T>C |
None |
M0123084 |
GKOOPNEP_00001 |
152 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1355A>G |
None |
M0123085 |
GKOOPNEP_00001 |
176 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1331C>T |
None |
M0123086 |
GKOOPNEP_00001 |
185 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1322G>T |
None |
M0123087 |
GKOOPNEP_00001 |
467 |
6 |
Oral |
0.40 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1040T>C |
None |
M0123088 |
GKOOPNEP_00001 |
620 |
6 |
Oral |
0.40 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*887T>C |
None |
M0123089 |
GKOOPNEP_00001 |
644 |
3 |
Oral |
0.20 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*863G>T |
None |
M0123090 |
GKOOPNEP_00001 |
749 |
6 |
Oral |
0.40 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*758G>A |
None |
M0123091 |
GKOOPNEP_00004 |
868 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4998T>A |
None |
M0123092 |
GKOOPNEP_00004 |
923 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4943T>C |
None |
M0123093 |
GKOOPNEP_00004 |
976 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4890T>C |
None |
M0123094 |
GKOOPNEP_00004 |
1058 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4808A>G |
None |
M0123095 |
GKOOPNEP_00004 |
1172 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4694C>A |
None |
M0123096 |
GKOOPNEP_00004 |
1373 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4493T>G |
None |
M0123097 |
GKOOPNEP_00004 |
1406 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4460T>C |
None |
M0123098 |
GKOOPNEP_00004 |
1424 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4442A>G |
None |
M0123099 |
GKOOPNEP_00004 |
1439 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4427A>T |
None |
M0123100 |
GKOOPNEP_00004 |
1500 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4366T>C |
None |
M0123101 |
GKOOPNEP_00001 |
1651 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1338C>T |
Asn446Asn |
M0123102 |
GKOOPNEP_00001 |
1933 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1056C>T |
Asn352Asn |
M0123103 |
GKOOPNEP_00001 |
2119 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
870T>C |
Asn290Asn |
M0123104 |
GKOOPNEP_00001 |
2188 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
801C>T |
Arg267Arg |
M0123105 |
GKOOPNEP_00001 |
2209 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
780C>T |
Gly260Gly |
M0123106 |
GKOOPNEP_00001 |
2245 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
744C>T |
Ser248Ser |
M0123107 |
GKOOPNEP_00001 |
2299 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
690T>C |
Gly230Gly |
M0123108 |
GKOOPNEP_00001 |
2449 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
540T>C |
Arg180Arg |
M0123109 |
GKOOPNEP_00001 |
2473 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
516T>C |
Asp172Asp |
M0123110 |
GKOOPNEP_00001 |
2482 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
507C>T |
Asp169Asp |
M0123111 |
GKOOPNEP_00001 |
2551 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
438G>A |
Lys146Lys |
M0123112 |
GKOOPNEP_00001 |
2587 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
402C>T |
Arg134Arg |
M0123113 |
GKOOPNEP_00001 |
2629 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
360A>G |
Val120Val |
M0123114 |
GKOOPNEP_00001 |
2641 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
348A>G |
Ser116Ser |
M0123115 |
GKOOPNEP_00001 |
2689 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
300C>T |
Asp100Asp |
M0123116 |
GKOOPNEP_00001 |
2848 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
141T>C |
Arg47Arg |
M0123117 |
GKOOPNEP_00001 |
2864 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
125C>T |
Ser42Phe |
M0123118 |
GKOOPNEP_00001 |
2870 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
119G>A |
Ser40Asn |
M0123119 |
GKOOPNEP_00001 |
2895 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
94C>A |
Pro32Thr |
M0123120 |
GKOOPNEP_00001 |
2959 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
30T>A |
Ala10Ala |
M0123121 |
GKOOPNEP_00002 |
3596 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
648A>G |
Leu216Leu |
M0123122 |
GKOOPNEP_00002 |
3628 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
616A>G |
Asn206Asp |
M0123123 |
GKOOPNEP_00002 |
3634 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
610A>G |
Asn204Asp |
M0123124 |
GKOOPNEP_00002 |
3793 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
451C>T |
Leu151Leu |
M0123125 |
GKOOPNEP_00002 |
3796 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
448T>C |
Leu150Leu |
M0123126 |
GKOOPNEP_00002 |
3806 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
438C>A |
Ile146Ile |
M0123127 |
GKOOPNEP_00002 |
3836 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
408C>T |
Ala136Ala |
M0123128 |
GKOOPNEP_00002 |
3890 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
354G>A |
Thr118Thr |
M0123129 |
GKOOPNEP_00002 |
3914 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
330T>C |
Pro110Pro |
M0123130 |
GKOOPNEP_00002 |
3917 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
327T>C |
Leu109Leu |
M0123131 |
GKOOPNEP_00002 |
3943 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
301T>C |
Leu101Leu |
M0123132 |
GKOOPNEP_00002 |
3944 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
300T>G |
Val100Val |
M0123133 |
GKOOPNEP_00002 |
3950 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
294A>T |
Arg98Arg |
M0123134 |
GKOOPNEP_00002 |
3995 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
249T>C |
Gly83Gly |
M0123135 |
GKOOPNEP_00002 |
4013 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
231A>G |
Thr77Thr |
M0123136 |
GKOOPNEP_00002 |
4058 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
186C>T |
Arg62Arg |
M0123137 |
GKOOPNEP_00002 |
4061 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
183G>A |
Glu61Glu |
M0123138 |
GKOOPNEP_00002 |
4106 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
138A>T |
Val46Val |
M0123139 |
GKOOPNEP_00003 |
4376 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1317C>T |
Thr439Thr |
M0123140 |
GKOOPNEP_00003 |
4385 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1308G>T |
Ala436Ala |
M0123141 |
GKOOPNEP_00003 |
4508 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1185C>T |
Asp395Asp |
M0123142 |
GKOOPNEP_00003 |
4514 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1179T>C |
Phe393Phe |
M0123143 |
GKOOPNEP_00003 |
4652 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1041A>T |
Pro347Pro |
M0123144 |
GKOOPNEP_00003 |
4718 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
975T>C |
Arg325Arg |
M0123145 |
GKOOPNEP_00003 |
4723 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
970C>A |
Arg324Arg |
M0123146 |
GKOOPNEP_00003 |
5279 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
414C>T |
Ser138Ser |
M0123147 |
GKOOPNEP_00003 |
5288 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
405C>T |
Cys135Cys |
M0123148 |
GKOOPNEP_00003 |
5474 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
219C>T |
Gly73Gly |
M0123149 |
GKOOPNEP_00001 |
5761 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2773T>C |
None |
M0123150 |
GKOOPNEP_00001 |
5859 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2871T>C |
None |
M0123151 |
GKOOPNEP_00006 |
7076 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
275T>C |
Leu92Ser |
M0123152 |
GKOOPNEP_00006 |
7087 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
286T>G |
Phe96Val |
M0123153 |
GKOOPNEP_00006 |
7311 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
510C>T |
Val170Val |
M0123154 |
GKOOPNEP_00006 |
7327 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
526C>T |
Leu176Leu |
M0123155 |
GKOOPNEP_00006 |
7374 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
573A>G |
Lys191Lys |
M0123156 |
GKOOPNEP_00006 |
7401 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
600A>G |
Ala200Ala |
M0123157 |
GKOOPNEP_00006 |
7407 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
606G>A |
Lys202Lys |
M0123158 |
GKOOPNEP_00006 |
7614 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
813T>C |
Tyr271Tyr |
M0123159 |
GKOOPNEP_00006 |
7713 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
912T>G |
Pro304Pro |
M0123160 |
GKOOPNEP_00003 |
10272 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4580C>G |
None |
M0123161 |
GKOOPNEP_00003 |
10275 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4583A>G |
None |
M0123162 |
GKOOPNEP_00003 |
10311 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4619T>C |
None |
M0123163 |
GKOOPNEP_00006 |
7416 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
615T>C |
Tyr205Tyr |
M0123164 |
GKOOPNEP_00003 |
10301 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4609A>T |
None |
M0123165 |
GKOOPNEP_00009 |
10603 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
126A>G |
Gln42Gln |
M0123166 |
GKOOPNEP_00009 |
10981 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
504T>C |
Asp168Asp |
M0123167 |
GKOOPNEP_00009 |
11200 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
723C>T |
His241His |
M0123168 |
GKOOPNEP_00011 |
11736 |
8 |
Oral |
0.53 |
protein_coding |
missense_variant |
MODERATE |
31A>G |
Thr11Ala |
M0123169 |
GKOOPNEP_00011 |
11921 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
216A>G |
Leu72Leu |
M0123170 |
GKOOPNEP_00011 |
12314 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
609T>C |
Asn203Asn |
M0123171 |
GKOOPNEP_00011 |
12374 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
669A>T |
Ala223Ala |
M0123172 |
GKOOPNEP_00011 |
12623 |
6 |
Oral |
0.40 |
protein_coding |
synonymous_variant |
LOW |
918G>A |
Gln306Gln |
M0123173 |
GKOOPNEP_00011 |
12684 |
6 |
Oral |
0.40 |
protein_coding |
missense_variant |
MODERATE |
979G>A |
Val327Ile |
M0123174 |
GKOOPNEP_00011 |
12707 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1002C>T |
Asp334Asp |
M0123175 |
GKOOPNEP_00011 |
12737 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1032A>G |
Leu344Leu |
M0123176 |
GKOOPNEP_00011 |
12771 |
7 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1066T>A |
Ser356Thr |
M0123177 |
GKOOPNEP_00011 |
12821 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1116C>T |
Tyr372Tyr |
M0123178 |
GKOOPNEP_00011 |
12896 |
7 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1191A>T |
Gly397Gly |
M0123179 |
GKOOPNEP_00010 |
12961 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1551G>A |
None |
M0123180 |
GKOOPNEP_00010 |
12982 |
7 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1572T>C |
None |
M0123181 |
GKOOPNEP_00010 |
12998 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1588C>T |
None |
M0123182 |
GKOOPNEP_00010 |
13136 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1726C>T |
None |
M0123183 |
GKOOPNEP_00010 |
13165 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1755A>G |
None |
M0123184 |
GKOOPNEP_00010 |
13184 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1774C>T |
None |
M0123185 |
GKOOPNEP_00010 |
13219 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1809C>T |
None |
M0123186 |
GKOOPNEP_00010 |
13426 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2016T>C |
None |
M0123187 |
GKOOPNEP_00010 |
13441 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2031G>A |
None |
M0123188 |
GKOOPNEP_00010 |
13580 |
7 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2170T>G |
None |
M0123189 |
GKOOPNEP_00010 |
13603 |
7 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2193G>A |
None |
M0123190 |
GKOOPNEP_00010 |
13627 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2217G>A |
None |
M0123191 |
GKOOPNEP_00010 |
13645 |
7 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2235A>G |
None |
M0123192 |
GKOOPNEP_00010 |
13744 |
7 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2334A>G |
None |
M0123193 |
GKOOPNEP_00010 |
13756 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2346A>G |
None |
M0123194 |
GKOOPNEP_00010 |
13813 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2403G>C |
None |
M0123195 |
GKOOPNEP_00010 |
13816 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2406G>A |
None |
M0123196 |
GKOOPNEP_00007 |
9512 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
544G>A |
Ala182Thr |
M0123197 |
GKOOPNEP_00008 |
10164 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
489G>A |
Lys163Lys |
M0123198 |
GKOOPNEP_00008 |
10203 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
528A>G |
Val176Val |
M0123199 |
GKOOPNEP_00009 |
10609 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
132T>C |
Asp44Asp |
M0123200 |
GKOOPNEP_00001 |
428 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1079T>A |
None |
M0123201 |
GKOOPNEP_00001 |
431 |
3 |
Oral |
0.20 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1076A>T |
None |
M0123202 |
GKOOPNEP_00001 |
434 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1073T>C |
None |
M0123203 |
GKOOPNEP_00001 |
479 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1028T>C |
None |
M0123204 |
GKOOPNEP_00001 |
503 |
4 |
Oral |
0.27 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1004T>C |
None |
M0123205 |
GKOOPNEP_00002 |
3902 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
342T>C |
Ser114Ser |
M0123206 |
GKOOPNEP_00002 |
4055 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
189C>T |
His63His |
M0123207 |
GKOOPNEP_00006 |
7599 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
798A>G |
Leu266Leu |
M0123208 |
GKOOPNEP_00006 |
7653 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
852C>T |
Asp284Asp |
M0123209 |
GKOOPNEP_00006 |
7665 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
864T>C |
Phe288Phe |
M0123210 |
GKOOPNEP_00006 |
7695 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
894C>T |
Ala298Ala |
M0123211 |
GKOOPNEP_00006 |
7929 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
1128G>A |
Glu376Glu |
M0123212 |
GKOOPNEP_00008 |
9897 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
222T>A |
Ile74Ile |
M0123213 |
GKOOPNEP_00008 |
10173 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
498T>A |
Ala166Ala |
M0123214 |
GKOOPNEP_00010 |
11481 |
6 |
Oral |
0.40 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-71G>A |
None |
M0123215 |
GKOOPNEP_00010 |
13195 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1785A>T |
None |
M0123216 |
GKOOPNEP_00010 |
13534 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2124G>A |
None |
M0123217 |
GKOOPNEP_00010 |
13710 |
4 |
Oral |
0.27 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2300G>A |
None |
M0123218 |
GKOOPNEP_00001 |
83 |
3 |
Oral |
0.20 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*1424T>C |
None |
M0123219 |
GKOOPNEP_00001 |
566 |
3 |
Oral |
0.20 |
protein_coding |
downstream_gene_variant |
MODIFIER |
*941G>A |
None |
M0123220 |
GKOOPNEP_00001 |
2317 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
672A>G |
Glu224Glu |
M0123221 |
GKOOPNEP_00002 |
3908 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
336C>A |
Val112Val |
M0123222 |
GKOOPNEP_00002 |
3911 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
333T>A |
Ser111Ser |
M0123223 |
GKOOPNEP_00008 |
9969 |
3 |
Oral |
0.20 |
protein_coding |
synonymous_variant |
LOW |
294A>G |
Ala98Ala |
M0123224 |
GKOOPNEP_00009 |
10548 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
71A>G |
Lys24Arg |
M0123225 |
GKOOPNEP_00010 |
11531 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-121T>C |
None |
M0123226 |
GKOOPNEP_00011 |
12287 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
582A>G |
Gln194Gln |
M0123227 |
GKOOPNEP_00011 |
12487 |
4 |
Oral |
0.27 |
protein_coding |
missense_variant |
MODERATE |
782G>C |
Ser261Thr |
M0123228 |
GKOOPNEP_00011 |
12551 |
5 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
846C>T |
Gly282Gly |
M0123229 |
GKOOPNEP_00010 |
12948 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1538G>A |
None |
M0123230 |
GKOOPNEP_00010 |
13495 |
5 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2085G>A |
None |
M0123231 |
GKOOPNEP_00010 |
13537 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2127G>A |
None |
M0123232 |
GKOOPNEP_00011 |
11765 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
60A>G |
Gly20Gly |
M0123233 |
GKOOPNEP_00011 |
12242 |
4 |
Oral |
0.27 |
protein_coding |
synonymous_variant |
LOW |
537C>T |
Ser179Ser |
M0123234 |
GKOOPNEP_00011 |
12583 |
3 |
Oral |
0.20 |
protein_coding |
missense_variant |
MODERATE |
878C>G |
Thr293Arg |
M0123235 |
GKOOPNEP_00010 |
13648 |
3 |
Oral |
0.20 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2238G>A |
None |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
GKOOPNEP_00001 |
EFC71364.1|GH125 |
91.7 |
0 |
1 |
493 |
1 |
1 |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |