Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C2410 |
Reference Plasmid |
1111525849768046_bin.37__k141_189825 |
Reference Plasmid Size |
11984 |
Reference Plasmid GC Content |
0.39 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0123236 |
HEKEBFMB_00001 |
206 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
411G>A |
Arg137Arg |
M0123237 |
HEKEBFMB_00001 |
215 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
402T>C |
Ser134Ser |
M0123238 |
HEKEBFMB_00001 |
323 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
294C>T |
His98His |
M0123239 |
HEKEBFMB_00001 |
398 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
219T>C |
Ser73Ser |
M0123240 |
HEKEBFMB_00001 |
446 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
171A>T |
Gly57Gly |
M0123241 |
HEKEBFMB_00001 |
509 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
108C>T |
Cys36Cys |
M0123242 |
HEKEBFMB_00002 |
621 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
321G>A |
Glu107Glu |
M0123243 |
HEKEBFMB_00002 |
695 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
247C>A |
Arg83Arg |
M0123244 |
HEKEBFMB_00002 |
696 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
246T>C |
Ala82Ala |
M0123245 |
HEKEBFMB_00002 |
780 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
162T>C |
Ile54Ile |
M0123246 |
HEKEBFMB_00002 |
826 |
10 |
Oral |
0.59 |
protein_coding |
missense_variant |
MODERATE |
116G>A |
Arg39His |
M0123247 |
HEKEBFMB_00002 |
834 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
108T>C |
Ser36Ser |
M0123248 |
HEKEBFMB_00001 |
1081 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-465T>C |
None |
M0123249 |
HEKEBFMB_00001 |
1195 |
10 |
Oral |
0.59 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-579T>C |
None |
M0123250 |
HEKEBFMB_00003 |
1359 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
117T>C |
Gly39Gly |
M0123251 |
HEKEBFMB_00003 |
1446 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
204T>A |
Ala68Ala |
M0123252 |
HEKEBFMB_00003 |
1464 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
222C>T |
Asn74Asn |
M0123253 |
HEKEBFMB_00003 |
1647 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
405A>T |
Ala135Ala |
M0123254 |
HEKEBFMB_00003 |
1788 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
546T>C |
Gly182Gly |
M0123255 |
HEKEBFMB_00003 |
1810 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
568T>C |
Leu190Leu |
M0123256 |
HEKEBFMB_00003 |
2019 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
777A>T |
Val259Val |
M0123257 |
HEKEBFMB_00003 |
2076 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
834T>A |
Ile278Ile |
M0123258 |
HEKEBFMB_00003 |
2406 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
1164T>C |
Asp388Asp |
M0123259 |
HEKEBFMB_00003 |
2598 |
10 |
Oral |
0.59 |
protein_coding |
missense_variant |
MODERATE |
1356G>C |
Glu452Asp |
M0123260 |
HEKEBFMB_00003 |
2628 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
1386T>A |
Pro462Pro |
M0123261 |
HEKEBFMB_00003 |
2652 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
1410C>T |
Ser470Ser |
M0123262 |
HEKEBFMB_00003 |
2751 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1509T>C |
His503His |
M0123263 |
HEKEBFMB_00003 |
2874 |
10 |
Oral |
0.59 |
protein_coding |
synonymous_variant |
LOW |
1632T>A |
Ala544Ala |
M0123264 |
HEKEBFMB_00001 |
3139 |
7 |
Oral |
0.41 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2523A>G |
None |
M0123265 |
HEKEBFMB_00004 |
3159 |
10 |
Oral |
0.59 |
protein_coding |
missense_variant |
MODERATE |
2237G>T |
Trp746Leu |
M0123266 |
HEKEBFMB_00004 |
3197 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
2199A>T |
Val733Val |
M0123267 |
HEKEBFMB_00004 |
3233 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
2163G>A |
Pro721Pro |
M0123268 |
HEKEBFMB_00004 |
3236 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
2160C>T |
Thr720Thr |
M0123269 |
HEKEBFMB_00004 |
3242 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
2154C>G |
Asp718Glu |
M0123270 |
HEKEBFMB_00004 |
4151 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1245T>C |
Ser415Ser |
M0123271 |
HEKEBFMB_00004 |
4253 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1143C>T |
Ser381Ser |
M0123272 |
HEKEBFMB_00004 |
4295 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
1101A>C |
Ala367Ala |
M0123273 |
HEKEBFMB_00004 |
4460 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
936A>G |
Ala312Ala |
M0123274 |
HEKEBFMB_00004 |
4499 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
897A>T |
Pro299Pro |
M0123275 |
HEKEBFMB_00004 |
4605 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
791A>G |
Lys264Arg |
M0123276 |
HEKEBFMB_00004 |
4607 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
789T>C |
His263His |
M0123277 |
HEKEBFMB_00004 |
4610 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
786A>T |
Val262Val |
M0123278 |
HEKEBFMB_00004 |
4673 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
723G>A |
Val241Val |
M0123279 |
HEKEBFMB_00004 |
4682 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
714A>G |
Ser238Ser |
M0123280 |
HEKEBFMB_00004 |
4829 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
567G>A |
Thr189Thr |
M0123281 |
HEKEBFMB_00004 |
4841 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
555C>T |
Leu185Leu |
M0123282 |
HEKEBFMB_00004 |
4865 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
531T>C |
Gly177Gly |
M0123283 |
HEKEBFMB_00004 |
5023 |
7 |
Oral |
0.41 |
protein_coding |
missense_variant |
MODERATE |
373A>G |
Ile125Val |
M0123284 |
HEKEBFMB_00004 |
5060 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
336T>C |
Phe112Phe |
M0123285 |
HEKEBFMB_00004 |
5165 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
231T>C |
Asp77Asp |
M0123286 |
HEKEBFMB_00004 |
5194 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
202G>A |
Val68Ile |
M0123287 |
HEKEBFMB_00004 |
5201 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
195A>T |
Ile65Ile |
M0123288 |
HEKEBFMB_00004 |
5316 |
7 |
Oral |
0.41 |
protein_coding |
missense_variant |
MODERATE |
80A>G |
Tyr27Cys |
M0123289 |
HEKEBFMB_00004 |
5317 |
7 |
Oral |
0.41 |
protein_coding |
missense_variant |
MODERATE |
79T>C |
Tyr27His |
M0123290 |
HEKEBFMB_00004 |
5351 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
45T>A |
Leu15Leu |
M0123291 |
HEKEBFMB_00004 |
5354 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
42T>A |
Ile14Ile |
M0123292 |
HEKEBFMB_00001 |
5399 |
7 |
Oral |
0.41 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4783G>A |
None |
M0123293 |
HEKEBFMB_00001 |
5468 |
6 |
Oral |
0.35 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4852C>T |
None |
M0123294 |
HEKEBFMB_00001 |
5526 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4910A>G |
None |
M0123295 |
HEKEBFMB_00001 |
5544 |
7 |
Oral |
0.41 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4928G>A |
None |
M0123296 |
HEKEBFMB_00005 |
5603 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1179G>T |
Glu393Asp |
M0123297 |
HEKEBFMB_00005 |
5711 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1071A>G |
Ala357Ala |
M0123298 |
HEKEBFMB_00005 |
5789 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
993C>T |
Ile331Ile |
M0123299 |
HEKEBFMB_00005 |
5841 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
941G>A |
Ser314Asn |
M0123300 |
HEKEBFMB_00005 |
5846 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
936C>T |
Ala312Ala |
M0123301 |
HEKEBFMB_00005 |
6077 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
705C>T |
Thr235Thr |
M0123302 |
HEKEBFMB_00005 |
6317 |
8 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
465G>T |
Glu155Asp |
M0123303 |
HEKEBFMB_00005 |
6362 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
420A>G |
Lys140Lys |
M0123304 |
HEKEBFMB_00005 |
6473 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
309A>T |
Thr103Thr |
M0123305 |
HEKEBFMB_00005 |
6500 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
282T>C |
Ile94Ile |
M0123306 |
HEKEBFMB_00005 |
6521 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
261A>T |
Ala87Ala |
M0123307 |
HEKEBFMB_00005 |
6614 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
168T>C |
Tyr56Tyr |
M0123308 |
HEKEBFMB_00004 |
6948 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1553A>T |
None |
M0123309 |
HEKEBFMB_00004 |
6986 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1591G>T |
None |
M0123310 |
HEKEBFMB_00006 |
7099 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
99A>G |
Leu33Leu |
M0123311 |
HEKEBFMB_00006 |
7147 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
147T>C |
Val49Val |
M0123312 |
HEKEBFMB_00006 |
7182 |
7 |
Oral |
0.41 |
protein_coding |
missense_variant |
MODERATE |
182A>G |
Glu61Gly |
M0123313 |
HEKEBFMB_00006 |
7411 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
411T>A |
Ala137Ala |
M0123314 |
HEKEBFMB_00007 |
7773 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
33C>T |
Asp11Asp |
M0123315 |
HEKEBFMB_00007 |
7791 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
51A>G |
Glu17Glu |
M0123316 |
HEKEBFMB_00007 |
7824 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
84T>C |
Phe28Phe |
M0123317 |
HEKEBFMB_00007 |
7899 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
159T>C |
Leu53Leu |
M0123318 |
HEKEBFMB_00007 |
7918 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
178A>G |
Met60Val |
M0123319 |
HEKEBFMB_00007 |
7950 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
210T>C |
Ala70Ala |
M0123320 |
HEKEBFMB_00007 |
7998 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
258A>C |
Ala86Ala |
M0123321 |
HEKEBFMB_00007 |
8064 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
324A>G |
Ala108Ala |
M0123322 |
HEKEBFMB_00007 |
8127 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
387G>A |
Lys129Lys |
M0123323 |
HEKEBFMB_00007 |
8202 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
462C>T |
Asn154Asn |
M0123324 |
HEKEBFMB_00004 |
8302 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2907A>G |
None |
M0123325 |
HEKEBFMB_00004 |
8308 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2913C>T |
None |
M0123326 |
HEKEBFMB_00004 |
8328 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2933T>C |
None |
M0123327 |
HEKEBFMB_00004 |
8331 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2936G>A |
None |
M0123328 |
HEKEBFMB_00004 |
8349 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2954C>T |
None |
M0123329 |
HEKEBFMB_00004 |
8374 |
6 |
Oral |
0.35 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2979C>T |
None |
M0123330 |
HEKEBFMB_00009 |
8797 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
177A>G |
Leu59Leu |
M0123331 |
HEKEBFMB_00009 |
8827 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
207T>C |
Pro69Pro |
M0123332 |
HEKEBFMB_00009 |
8839 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
219A>G |
Leu73Leu |
M0123333 |
HEKEBFMB_00009 |
8848 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
228A>G |
Ala76Ala |
M0123334 |
HEKEBFMB_00009 |
8869 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
249G>A |
Ser83Ser |
M0123335 |
HEKEBFMB_00009 |
8875 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
255A>G |
Ala85Ala |
M0123336 |
HEKEBFMB_00009 |
8929 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
309T>C |
Ile103Ile |
M0123337 |
HEKEBFMB_00009 |
9025 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
405A>T |
Glu135Asp |
M0123338 |
HEKEBFMB_00009 |
9120 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
500A>G |
Asp167Gly |
M0123339 |
HEKEBFMB_00009 |
9121 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
501C>T |
Asp167Asp |
M0123340 |
HEKEBFMB_00009 |
9193 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
573A>G |
Leu191Leu |
M0123341 |
HEKEBFMB_00009 |
9211 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
591G>A |
Glu197Glu |
M0123342 |
HEKEBFMB_00009 |
9220 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
600C>T |
Ile200Ile |
M0123343 |
HEKEBFMB_00009 |
9268 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
648A>G |
Leu216Leu |
M0123344 |
HEKEBFMB_00009 |
9301 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
681A>T |
Pro227Pro |
M0123345 |
HEKEBFMB_00009 |
9478 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
858G>C |
Glu286Asp |
M0123346 |
HEKEBFMB_00009 |
9499 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
879A>G |
Leu293Leu |
M0123347 |
HEKEBFMB_00004 |
9659 |
7 |
Oral |
0.41 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4264T>C |
None |
M0123348 |
HEKEBFMB_00004 |
9660 |
8 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4265C>T |
None |
M0123349 |
HEKEBFMB_00004 |
9752 |
6 |
Oral |
0.35 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4357G>A |
None |
M0123350 |
HEKEBFMB_00004 |
9776 |
8 |
Oral |
0.47 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4381C>G |
None |
M0123351 |
HEKEBFMB_00010 |
9823 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1744C>T |
Leu582Leu |
M0123352 |
HEKEBFMB_00010 |
9876 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
1691G>C |
Ser564Thr |
M0123353 |
HEKEBFMB_00010 |
9992 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1575T>C |
Thr525Thr |
M0123354 |
HEKEBFMB_00010 |
10073 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
1494T>A |
Ala498Ala |
M0123355 |
HEKEBFMB_00010 |
10076 |
9 |
Oral |
0.53 |
protein_coding |
missense_variant |
MODERATE |
1491A>G |
Ile497Met |
M0123356 |
HEKEBFMB_00010 |
10088 |
8 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1479A>T |
Lys493Asn |
M0123357 |
HEKEBFMB_00010 |
10092 |
8 |
Oral |
0.47 |
protein_coding |
missense_variant |
MODERATE |
1475A>C |
Gln492Pro |
M0123358 |
HEKEBFMB_00010 |
10112 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1455G>A |
Ser485Ser |
M0123359 |
HEKEBFMB_00010 |
10280 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1287C>T |
Ala429Ala |
M0123360 |
HEKEBFMB_00010 |
10283 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1284A>G |
Lys428Lys |
M0123361 |
HEKEBFMB_00010 |
10346 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1221A>G |
Ala407Ala |
M0123362 |
HEKEBFMB_00010 |
10353 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
1214A>C |
Gln405Pro |
M0123363 |
HEKEBFMB_00010 |
10487 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1080A>G |
Ala360Ala |
M0123364 |
HEKEBFMB_00010 |
10507 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1060T>C |
Leu354Leu |
M0123365 |
HEKEBFMB_00010 |
10529 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
1038T>C |
Ser346Ser |
M0123366 |
HEKEBFMB_00010 |
10538 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1029G>A |
Lys343Lys |
M0123367 |
HEKEBFMB_00010 |
10652 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
915C>A |
Leu305Leu |
M0123368 |
HEKEBFMB_00010 |
10697 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
870T>C |
His290His |
M0123369 |
HEKEBFMB_00010 |
10733 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
834T>C |
Phe278Phe |
M0123370 |
HEKEBFMB_00010 |
10736 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
831C>A |
Gly277Gly |
M0123371 |
HEKEBFMB_00010 |
10769 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
798A>G |
Leu266Leu |
M0123372 |
HEKEBFMB_00010 |
10790 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
777T>C |
Leu259Leu |
M0123373 |
HEKEBFMB_00010 |
10808 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
759G>A |
Lys253Lys |
M0123374 |
HEKEBFMB_00010 |
10871 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
696T>C |
Gly232Gly |
M0123375 |
HEKEBFMB_00010 |
10895 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
672T>C |
Asp224Asp |
M0123376 |
HEKEBFMB_00010 |
11015 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
552T>C |
Asp184Asp |
M0123377 |
HEKEBFMB_00010 |
11207 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
360A>T |
Gly120Gly |
M0123378 |
HEKEBFMB_00010 |
11234 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
333A>G |
Glu111Glu |
M0123379 |
HEKEBFMB_00010 |
11267 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
300C>T |
Asn100Asn |
M0123380 |
HEKEBFMB_00010 |
11276 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
291T>G |
Ala97Ala |
M0123381 |
HEKEBFMB_00010 |
11288 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
279C>T |
Phe93Phe |
M0123382 |
HEKEBFMB_00010 |
11359 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
208C>G |
Pro70Ala |
M0123383 |
HEKEBFMB_00010 |
11411 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
156A>G |
Lys52Lys |
M0123384 |
HEKEBFMB_00005 |
11685 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4904C>A |
None |
M0123385 |
HEKEBFMB_00010 |
11790 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-224C>T |
None |
M0123386 |
HEKEBFMB_00010 |
11904 |
6 |
Oral |
0.35 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-338A>G |
None |
M0123387 |
HEKEBFMB_00001 |
5546 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4930G>A |
None |
M0123388 |
HEKEBFMB_00001 |
5555 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4939T>C |
None |
M0123389 |
HEKEBFMB_00005 |
5636 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1146C>T |
Thr382Thr |
M0123390 |
HEKEBFMB_00005 |
5642 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1140C>T |
His380His |
M0123391 |
HEKEBFMB_00005 |
5648 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1134C>T |
Gly378Gly |
M0123392 |
HEKEBFMB_00005 |
5669 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1113A>T |
Ala371Ala |
M0123393 |
HEKEBFMB_00005 |
5681 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1101C>A |
Pro367Pro |
M0123394 |
HEKEBFMB_00005 |
5693 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1089A>T |
Gly363Gly |
M0123395 |
HEKEBFMB_00005 |
6269 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
513T>C |
Asp171Asp |
M0123396 |
HEKEBFMB_00005 |
6293 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
489T>C |
Asp163Asp |
M0123397 |
HEKEBFMB_00005 |
6314 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
468C>T |
His156His |
M0123398 |
HEKEBFMB_00005 |
6392 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
390C>T |
Asp130Asp |
M0123399 |
HEKEBFMB_00005 |
6422 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
360G>A |
Ala120Ala |
M0123400 |
HEKEBFMB_00005 |
6707 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
75C>T |
Pro25Pro |
M0123401 |
HEKEBFMB_00001 |
365 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
252A>T |
Val84Val |
M0123402 |
HEKEBFMB_00001 |
449 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
168A>G |
Gln56Gln |
M0123403 |
HEKEBFMB_00001 |
476 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
141A>C |
Thr47Thr |
M0123404 |
HEKEBFMB_00002 |
753 |
9 |
Oral |
0.53 |
protein_coding |
synonymous_variant |
LOW |
189G>A |
Glu63Glu |
M0123405 |
HEKEBFMB_00002 |
813 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
129T>C |
Leu43Leu |
M0123406 |
HEKEBFMB_00002 |
821 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
121G>A |
Val41Ile |
M0123407 |
HEKEBFMB_00002 |
878 |
9 |
Oral |
0.53 |
protein_coding |
missense_variant |
MODERATE |
64T>C |
Phe22Leu |
M0123408 |
HEKEBFMB_00001 |
1242 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-626A>G |
None |
M0123409 |
HEKEBFMB_00003 |
1272 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
30T>A |
Val10Val |
M0123410 |
HEKEBFMB_00003 |
1323 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
81G>A |
Gln27Gln |
M0123411 |
HEKEBFMB_00003 |
1581 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
339C>T |
Asp113Asp |
M0123412 |
HEKEBFMB_00003 |
2355 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1113G>A |
Leu371Leu |
M0123413 |
HEKEBFMB_00003 |
2430 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1188C>T |
Leu396Leu |
M0123414 |
HEKEBFMB_00003 |
2793 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1551G>A |
Val517Val |
M0123415 |
HEKEBFMB_00003 |
3007 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
1765C>T |
Pro589Ser |
M0123416 |
HEKEBFMB_00001 |
3049 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2433G>C |
None |
M0123417 |
HEKEBFMB_00001 |
3051 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2435G>A |
None |
M0123418 |
HEKEBFMB_00004 |
3383 |
8 |
Oral |
0.47 |
protein_coding |
synonymous_variant |
LOW |
2013G>A |
Leu671Leu |
M0123419 |
HEKEBFMB_00004 |
3397 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1999C>G |
Leu667Val |
M0123420 |
HEKEBFMB_00004 |
3428 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
1968G>T |
Met656Ile |
M0123421 |
HEKEBFMB_00004 |
3429 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
1967T>C |
Met656Thr |
M0123422 |
HEKEBFMB_00004 |
3440 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
1956T>C |
Asp652Asp |
M0123423 |
HEKEBFMB_00004 |
3443 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
1953T>C |
Ser651Ser |
M0123424 |
HEKEBFMB_00004 |
3487 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
1909T>G |
Ser637Ala |
M0123425 |
HEKEBFMB_00004 |
3503 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
1893C>G |
Ile631Met |
M0123426 |
HEKEBFMB_00004 |
3505 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
1891A>T |
Ile631Phe |
M0123427 |
HEKEBFMB_00004 |
3506 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1890T>A |
Arg630Arg |
M0123428 |
HEKEBFMB_00004 |
3521 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1875G>A |
Leu625Leu |
M0123429 |
HEKEBFMB_00004 |
3524 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1872T>C |
Ile624Ile |
M0123430 |
HEKEBFMB_00004 |
3569 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1827G>A |
Glu609Glu |
M0123431 |
HEKEBFMB_00004 |
3620 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1776C>T |
Ile592Ile |
M0123432 |
HEKEBFMB_00004 |
3629 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1767C>T |
Asp589Asp |
M0123433 |
HEKEBFMB_00004 |
3695 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1701A>G |
Arg567Arg |
M0123434 |
HEKEBFMB_00004 |
3836 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1560C>A |
Ile520Ile |
M0123435 |
HEKEBFMB_00004 |
3911 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1485C>T |
Ser495Ser |
M0123436 |
HEKEBFMB_00004 |
3926 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1470A>G |
Val490Val |
M0123437 |
HEKEBFMB_00004 |
4040 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1356C>T |
Ser452Ser |
M0123438 |
HEKEBFMB_00004 |
4041 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
1355G>C |
Ser452Thr |
M0123439 |
HEKEBFMB_00004 |
4042 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
1354A>T |
Ser452Cys |
M0123440 |
HEKEBFMB_00004 |
4049 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1347T>C |
Phe449Phe |
M0123441 |
HEKEBFMB_00004 |
4053 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1343T>C |
Leu448Pro |
M0123442 |
HEKEBFMB_00004 |
4084 |
6 |
Oral |
0.35 |
protein_coding |
missense_variant |
MODERATE |
1312A>G |
Ile438Val |
M0123443 |
HEKEBFMB_00004 |
4157 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1239G>A |
Ser413Ser |
M0123444 |
HEKEBFMB_00004 |
4220 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1176G>T |
Val392Val |
M0123445 |
HEKEBFMB_00004 |
4243 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1153C>G |
Leu385Val |
M0123446 |
HEKEBFMB_00004 |
4256 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1140G>A |
Lys380Lys |
M0123447 |
HEKEBFMB_00004 |
4262 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1134G>C |
Val378Val |
M0123448 |
HEKEBFMB_00004 |
4292 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1104G>A |
Ser368Ser |
M0123449 |
HEKEBFMB_00004 |
4298 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1098T>A |
Ala366Ala |
M0123450 |
HEKEBFMB_00004 |
4331 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1065T>C |
Val355Val |
M0123451 |
HEKEBFMB_00004 |
4361 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1035C>T |
Ile345Ile |
M0123452 |
HEKEBFMB_00004 |
4382 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
1014A>G |
Gln338Gln |
M0123453 |
HEKEBFMB_00004 |
4463 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
933A>G |
Gln311Gln |
M0123454 |
HEKEBFMB_00004 |
4492 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
904A>G |
Ser302Gly |
M0123455 |
HEKEBFMB_00004 |
4565 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
831A>T |
Gly277Gly |
M0123456 |
HEKEBFMB_00004 |
4571 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
825T>A |
Leu275Leu |
M0123457 |
HEKEBFMB_00004 |
4574 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
822C>T |
Asp274Asp |
M0123458 |
HEKEBFMB_00004 |
4583 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
813T>A |
Pro271Pro |
M0123459 |
HEKEBFMB_00004 |
4604 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
792G>A |
Lys264Lys |
M0123460 |
HEKEBFMB_00004 |
4625 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
771A>C |
Ala257Ala |
M0123461 |
HEKEBFMB_00004 |
4628 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
768G>A |
Leu256Leu |
M0123462 |
HEKEBFMB_00004 |
4747 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
649A>C |
Ile217Leu |
M0123463 |
HEKEBFMB_00004 |
4832 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
564C>A |
Ile188Ile |
M0123464 |
HEKEBFMB_00004 |
4850 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
546T>A |
Ser182Ser |
M0123465 |
HEKEBFMB_00004 |
4868 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
528G>A |
Gly176Gly |
M0123466 |
HEKEBFMB_00004 |
4910 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
486A>G |
Val162Val |
M0123467 |
HEKEBFMB_00004 |
4913 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
483T>C |
Asp161Asp |
M0123468 |
HEKEBFMB_00004 |
4919 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
477C>T |
Ile159Ile |
M0123469 |
HEKEBFMB_00004 |
4940 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
456G>A |
Leu152Leu |
M0123470 |
HEKEBFMB_00004 |
4991 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
405A>G |
Val135Val |
M0123471 |
HEKEBFMB_00004 |
5084 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
312C>T |
Ile104Ile |
M0123472 |
HEKEBFMB_00004 |
5108 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
288T>C |
Gly96Gly |
M0123473 |
HEKEBFMB_00004 |
5111 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
285G>A |
Leu95Leu |
M0123474 |
HEKEBFMB_00004 |
5192 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
204T>A |
Val68Val |
M0123475 |
HEKEBFMB_00004 |
5222 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
174C>T |
Asp58Asp |
M0123476 |
HEKEBFMB_00004 |
5231 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
165T>C |
Asp55Asp |
M0123477 |
HEKEBFMB_00004 |
5243 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
153C>T |
Pro51Pro |
M0123478 |
HEKEBFMB_00004 |
5246 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
150T>C |
Thr50Thr |
M0123479 |
HEKEBFMB_00004 |
5339 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
57C>T |
Gly19Gly |
M0123480 |
HEKEBFMB_00001 |
5396 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4780A>G |
None |
M0123481 |
HEKEBFMB_00005 |
5837 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
945T>C |
Asp315Asp |
M0123482 |
HEKEBFMB_00005 |
5843 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
939T>C |
Ile313Ile |
M0123483 |
HEKEBFMB_00005 |
5910 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
872G>A |
Ser291Asn |
M0123484 |
HEKEBFMB_00005 |
6011 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
771A>G |
Glu257Glu |
M0123485 |
HEKEBFMB_00005 |
6182 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
600C>T |
Gly200Gly |
M0123486 |
HEKEBFMB_00005 |
6194 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
588C>T |
Gly196Gly |
M0123487 |
HEKEBFMB_00005 |
6245 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
537T>C |
His179His |
M0123488 |
HEKEBFMB_00005 |
6248 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
534G>A |
Ala178Ala |
M0123489 |
HEKEBFMB_00005 |
6524 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
258T>C |
Gly86Gly |
M0123490 |
HEKEBFMB_00005 |
6545 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
237C>T |
Asp79Asp |
M0123491 |
HEKEBFMB_00004 |
6933 |
4 |
Oral |
0.24 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1538A>C |
None |
M0123492 |
HEKEBFMB_00004 |
6937 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1542T>C |
None |
M0123493 |
HEKEBFMB_00004 |
6940 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1545T>C |
None |
M0123494 |
HEKEBFMB_00006 |
7069 |
6 |
Oral |
0.35 |
protein_coding |
synonymous_variant |
LOW |
69C>A |
Pro23Pro |
M0123495 |
HEKEBFMB_00006 |
7162 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
162G>A |
Ser54Ser |
M0123496 |
HEKEBFMB_00006 |
7174 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
174C>T |
Tyr58Tyr |
M0123497 |
HEKEBFMB_00006 |
7315 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
315A>T |
Ala105Ala |
M0123498 |
HEKEBFMB_00006 |
7318 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
318T>C |
Leu106Leu |
M0123499 |
HEKEBFMB_00006 |
7327 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
327C>A |
Ala109Ala |
M0123500 |
HEKEBFMB_00006 |
7336 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
336A>G |
Ser112Ser |
M0123501 |
HEKEBFMB_00006 |
7372 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
372T>C |
Val124Val |
M0123502 |
HEKEBFMB_00006 |
7567 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
567A>G |
Leu189Leu |
M0123503 |
HEKEBFMB_00006 |
7606 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
606T>C |
Ser202Ser |
M0123504 |
HEKEBFMB_00006 |
7656 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
656A>G |
Asn219Ser |
M0123505 |
HEKEBFMB_00006 |
7660 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
660A>T |
Ile220Ile |
M0123506 |
HEKEBFMB_00007 |
7947 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
207T>A |
Ala69Ala |
M0123507 |
HEKEBFMB_00007 |
8079 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
339T>C |
Ala113Ala |
M0123508 |
HEKEBFMB_00004 |
8291 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2896A>T |
None |
M0123509 |
HEKEBFMB_00004 |
8409 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3014G>A |
None |
M0123510 |
HEKEBFMB_00009 |
8665 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
45T>C |
Asn15Asn |
M0123511 |
HEKEBFMB_00009 |
8833 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
213G>A |
Lys71Lys |
M0123512 |
HEKEBFMB_00009 |
8845 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
225T>C |
Asp75Asp |
M0123513 |
HEKEBFMB_00009 |
8920 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
300A>T |
Gly100Gly |
M0123514 |
HEKEBFMB_00009 |
9067 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
447C>T |
Arg149Arg |
M0123515 |
HEKEBFMB_00009 |
9112 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
492C>A |
Thr164Thr |
M0123516 |
HEKEBFMB_00009 |
9460 |
4 |
Oral |
0.24 |
protein_coding |
missense_variant |
MODERATE |
840T>A |
Asp280Glu |
M0123517 |
HEKEBFMB_00004 |
9675 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4280G>A |
None |
M0123518 |
HEKEBFMB_00004 |
9676 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4281T>G |
None |
M0123519 |
HEKEBFMB_00004 |
9678 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4283T>A |
None |
M0123520 |
HEKEBFMB_00004 |
9680 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4285C>A |
None |
M0123521 |
HEKEBFMB_00004 |
9681 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4286T>C |
None |
M0123522 |
HEKEBFMB_00010 |
10093 |
3 |
Oral |
0.18 |
protein_coding |
stop_gained |
HIGH |
1474C>T |
Gln492* |
M0123523 |
HEKEBFMB_00010 |
10133 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1434T>C |
Asp478Asp |
M0123524 |
HEKEBFMB_00010 |
10145 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1422C>T |
Phe474Phe |
M0123525 |
HEKEBFMB_00010 |
10520 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1047C>T |
Ala349Ala |
M0123526 |
HEKEBFMB_00010 |
10631 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
936G>A |
Leu312Leu |
M0123527 |
HEKEBFMB_00010 |
10916 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
651T>A |
Arg217Arg |
M0123528 |
HEKEBFMB_00010 |
11108 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
459T>C |
Ile153Ile |
M0123529 |
HEKEBFMB_00010 |
11135 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
432G>A |
Thr144Thr |
M0123530 |
HEKEBFMB_00010 |
11228 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
339A>C |
Thr113Thr |
M0123531 |
HEKEBFMB_00010 |
11916 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-350G>A |
None |
M0123532 |
HEKEBFMB_00002 |
741 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
201A>G |
Arg67Arg |
M0123533 |
HEKEBFMB_00001 |
1000 |
5 |
Oral |
0.29 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-384C>G |
None |
M0123534 |
HEKEBFMB_00003 |
2473 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1231A>G |
Ile411Val |
M0123535 |
HEKEBFMB_00004 |
3200 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
2196C>T |
Asp732Asp |
M0123536 |
HEKEBFMB_00004 |
3284 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
2112A>T |
Arg704Arg |
M0123537 |
HEKEBFMB_00004 |
3335 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
2061G>A |
Lys687Lys |
M0123538 |
HEKEBFMB_00004 |
3370 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
2026C>A |
Arg676Arg |
M0123539 |
HEKEBFMB_00004 |
3646 |
3 |
Oral |
0.18 |
protein_coding |
missense_variant |
MODERATE |
1750A>C |
Asn584His |
M0123540 |
HEKEBFMB_00004 |
3647 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1749T>C |
Arg583Arg |
M0123541 |
HEKEBFMB_00004 |
3662 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
1734G>A |
Lys578Lys |
M0123542 |
HEKEBFMB_00004 |
3665 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1731C>T |
Asn577Asn |
M0123543 |
HEKEBFMB_00004 |
3668 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1728C>T |
His576His |
M0123544 |
HEKEBFMB_00004 |
3671 |
7 |
Oral |
0.41 |
protein_coding |
synonymous_variant |
LOW |
1725G>T |
Gly575Gly |
M0123545 |
HEKEBFMB_00004 |
3677 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1719G>A |
Val573Val |
M0123546 |
HEKEBFMB_00004 |
3737 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1659G>A |
Thr553Thr |
M0123547 |
HEKEBFMB_00004 |
4028 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1368C>T |
His456His |
M0123548 |
HEKEBFMB_00004 |
4736 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
660C>T |
Asn220Asn |
M0123549 |
HEKEBFMB_00004 |
5075 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
321G>T |
Thr107Thr |
M0123550 |
HEKEBFMB_00010 |
9887 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1680G>A |
Lys560Lys |
M0123551 |
HEKEBFMB_00010 |
9972 |
5 |
Oral |
0.29 |
protein_coding |
missense_variant |
MODERATE |
1595C>T |
Ala532Val |
M0123552 |
HEKEBFMB_00010 |
10091 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1476A>G |
Gln492Gln |
M0123553 |
HEKEBFMB_00010 |
11513 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
54A>T |
Thr18Thr |
M0123554 |
HEKEBFMB_00001 |
533 |
5 |
Oral |
0.29 |
protein_coding |
synonymous_variant |
LOW |
84C>T |
Phe28Phe |
M0123555 |
HEKEBFMB_00003 |
2574 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
1332C>T |
Asn444Asn |
M0123556 |
HEKEBFMB_00003 |
2922 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1680A>T |
Ala560Ala |
M0123557 |
HEKEBFMB_00003 |
2931 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1689A>T |
Gly563Gly |
M0123558 |
HEKEBFMB_00001 |
3102 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2486A>G |
None |
M0123559 |
HEKEBFMB_00001 |
3104 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2488A>G |
None |
M0123560 |
HEKEBFMB_00001 |
3123 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2507A>T |
None |
M0123561 |
HEKEBFMB_00001 |
3124 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2508G>A |
None |
M0123562 |
HEKEBFMB_00001 |
5556 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4940A>T |
None |
M0123563 |
HEKEBFMB_00005 |
6041 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
741C>T |
Thr247Thr |
M0123564 |
HEKEBFMB_00010 |
10991 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
576G>A |
Val192Val |
M0123565 |
HEKEBFMB_00004 |
3482 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1914A>T |
Thr638Thr |
M0123566 |
HEKEBFMB_00004 |
4787 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
609C>T |
Gly203Gly |
M0123567 |
HEKEBFMB_00004 |
5102 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
294C>T |
Val98Val |
M0123568 |
HEKEBFMB_00004 |
5234 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
162T>A |
Val54Val |
M0123569 |
HEKEBFMB_00001 |
5431 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4815T>C |
None |
M0123570 |
HEKEBFMB_00001 |
5488 |
3 |
Oral |
0.18 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-4872A>T |
None |
M0123571 |
HEKEBFMB_00001 |
278 |
4 |
Oral |
0.24 |
protein_coding |
synonymous_variant |
LOW |
339A>G |
Lys113Lys |
M0123572 |
HEKEBFMB_00003 |
2265 |
3 |
Oral |
0.18 |
protein_coding |
synonymous_variant |
LOW |
1023G>A |
Lys341Lys |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |