Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2430
  Reference Plasmid   1111525849768046_bin.37__k141_224633
  Reference Plasmid Size   2738
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0125297 BLAEGADJ_00001 52 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1691T>A None
M0125298 BLAEGADJ_00001 70 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1673T>C None
M0125299 BLAEGADJ_00001 103 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1640A>G None
M0125300 BLAEGADJ_00001 118 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1625A>T None
M0125301 BLAEGADJ_00001 178 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *1565C>T None
M0125302 BLAEGADJ_00001 219 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1524G>A None
M0125303 BLAEGADJ_00001 229 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *1514C>T None
M0125304 BLAEGADJ_00001 234 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1509T>A None
M0125305 BLAEGADJ_00001 235 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1508C>G None
M0125306 BLAEGADJ_00001 271 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1472G>A None
M0125307 BLAEGADJ_00001 295 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1448T>A None
M0125308 BLAEGADJ_00001 300 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *1443A>G None
M0125309 BLAEGADJ_00001 304 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *1439A>G None
M0125310 BLAEGADJ_00001 320 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1423C>G None
M0125311 BLAEGADJ_00001 321 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1422G>A None
M0125312 BLAEGADJ_00001 322 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1421A>T None
M0125313 BLAEGADJ_00001 330 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *1413T>C None
M0125314 BLAEGADJ_00001 333 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1410A>T None
M0125315 BLAEGADJ_00001 408 8 Oral 0.89 protein_coding downstream_gene_variant MODIFIER *1335T>G None
M0125316 BLAEGADJ_00001 439 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *1304C>T None
M0125317 BLAEGADJ_00001 463 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *1280C>T None
M0125318 BLAEGADJ_00001 472 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *1271G>A None
M0125319 BLAEGADJ_00001 481 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1262A>T None
M0125320 BLAEGADJ_00001 508 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1235T>A None
M0125321 BLAEGADJ_00001 694 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *1049C>T None
M0125322 BLAEGADJ_00001 790 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *953A>T None
M0125323 BLAEGADJ_00001 793 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *950T>C None
M0125324 BLAEGADJ_00001 794 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *949G>A None
M0125325 BLAEGADJ_00001 796 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *947T>C None
M0125326 BLAEGADJ_00001 805 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *938T>C None
M0125327 BLAEGADJ_00001 859 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *884T>C None
M0125328 BLAEGADJ_00001 936 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *807T>C None
M0125329 BLAEGADJ_00001 996 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *747A>T None
M0125330 BLAEGADJ_00001 1003 5 Oral 0.56 protein_coding downstream_gene_variant MODIFIER *740T>G None
M0125331 BLAEGADJ_00001 1027 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *716A>G None
M0125332 BLAEGADJ_00001 1045 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *698A>T None
M0125333 BLAEGADJ_00001 1051 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *692A>G None
M0125334 BLAEGADJ_00001 1057 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *686A>T None
M0125335 BLAEGADJ_00001 1075 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *668A>C None
M0125336 BLAEGADJ_00001 1093 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *650C>T None
M0125337 BLAEGADJ_00001 1177 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *566A>G None
M0125338 BLAEGADJ_00001 1192 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *551T>C None
M0125339 BLAEGADJ_00001 1219 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *524T>A None
M0125340 BLAEGADJ_00001 1231 6 Oral 0.67 protein_coding downstream_gene_variant MODIFIER *512C>T None
M0125341 BLAEGADJ_00001 1249 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *494A>G None
M0125342 BLAEGADJ_00001 1499 7 Oral 0.78 protein_coding downstream_gene_variant MODIFIER *244T>G None
M0125343 BLAEGADJ_00001 1558 5 Oral 0.56 protein_coding downstream_gene_variant MODIFIER *185C>A None
M0125344 BLAEGADJ_00001 1591 4 Oral 0.44 protein_coding downstream_gene_variant MODIFIER *152C>A None
M0125345 BLAEGADJ_00001 1651 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *92T>C None
M0125346 BLAEGADJ_00001 1699 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *44C>T None
M0125347 BLAEGADJ_00001 1714 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *29T>G None
M0125348 BLAEGADJ_00001 1741 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *2C>T None
M0125349 BLAEGADJ_00001 1771 3 Oral 0.33 protein_coding missense_variant MODERATE 101A>T Lys34Met
M0125350 BLAEGADJ_00001 2005 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -134C>T None
M0125351 BLAEGADJ_00001 2634 4 Oral 0.44 protein_coding upstream_gene_variant MODIFIER -763G>A None
M0125352 BLAEGADJ_00001 259 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *1484T>A None
M0125353 BLAEGADJ_00001 604 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *1139C>A None
M0125354 BLAEGADJ_00001 2150 3 Oral 0.33 protein_coding upstream_gene_variant MODIFIER -279C>A None
M0125355 BLAEGADJ_00001 142 3 Oral 0.33 protein_coding downstream_gene_variant MODIFIER *1601C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term