Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2431
  Reference Plasmid   1111525849768046_bin.37__k141_225527
  Reference Plasmid Size   4491
  Reference Plasmid GC Content   0.41
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0125356 CBFCNCDH_00001 782 4 Oral 0.67 protein_coding synonymous_variant LOW 759T>G Val253Val
M0125357 CBFCNCDH_00001 932 4 Oral 0.67 protein_coding synonymous_variant LOW 609A>C Ala203Ala
M0125358 CBFCNCDH_00001 1031 3 Oral 0.50 protein_coding synonymous_variant LOW 510T>C Gly170Gly
M0125359 CBFCNCDH_00001 1097 3 Oral 0.50 protein_coding synonymous_variant LOW 444C>T Thr148Thr
M0125360 CBFCNCDH_00001 1322 3 Oral 0.50 protein_coding synonymous_variant LOW 219T>C Phe73Phe
M0125361 CBFCNCDH_00001 1568 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -28A>G None
M0125362 CBFCNCDH_00002 1685 4 Oral 0.67 protein_coding missense_variant MODERATE 97A>G Thr33Ala
M0125363 CBFCNCDH_00003 1786 3 Oral 0.50 protein_coding missense_variant MODERATE 1744C>T His582Tyr
M0125364 CBFCNCDH_00003 1790 3 Oral 0.50 protein_coding synonymous_variant LOW 1740G>A Glu580Glu
M0125365 CBFCNCDH_00003 2016 4 Oral 0.67 protein_coding missense_variant MODERATE 1514A>G Asp505Gly
M0125366 CBFCNCDH_00003 2551 4 Oral 0.67 protein_coding missense_variant MODERATE 979A>C Asn327His
M0125367 CBFCNCDH_00003 2588 3 Oral 0.50 protein_coding synonymous_variant LOW 942A>G Val314Val
M0125368 CBFCNCDH_00003 2735 3 Oral 0.50 protein_coding synonymous_variant LOW 795T>C Ser265Ser
M0125369 CBFCNCDH_00003 2816 4 Oral 0.67 protein_coding synonymous_variant LOW 714C>T Ala238Ala
M0125370 CBFCNCDH_00003 2842 3 Oral 0.50 protein_coding synonymous_variant LOW 688T>C Leu230Leu
M0125371 CBFCNCDH_00003 3148 3 Oral 0.50 protein_coding missense_variant MODERATE 382A>G Thr128Ala
M0125372 CBFCNCDH_00001 3642 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -2102C>T None
M0125373 CBFCNCDH_00004 4223 3 Oral 0.50 protein_coding missense_variant MODERATE 238G>A Val80Ile
M0125374 CBFCNCDH_00002 85 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1504G>A None
M0125375 CBFCNCDH_00002 217 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1372G>A None
M0125376 CBFCNCDH_00002 268 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1321G>A None
M0125377 CBFCNCDH_00002 270 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1319T>G None
M0125378 CBFCNCDH_00001 506 3 Oral 0.50 protein_coding synonymous_variant LOW 1035A>G Leu345Leu
M0125379 CBFCNCDH_00001 713 3 Oral 0.50 protein_coding synonymous_variant LOW 828G>A Gly276Gly
M0125380 CBFCNCDH_00001 737 3 Oral 0.50 protein_coding synonymous_variant LOW 804A>G Val268Val
M0125381 CBFCNCDH_00001 998 3 Oral 0.50 protein_coding synonymous_variant LOW 543G>A Val181Val
M0125382 CBFCNCDH_00001 1118 3 Oral 0.50 protein_coding synonymous_variant LOW 423T>C Gly141Gly
M0125383 CBFCNCDH_00003 1757 3 Oral 0.50 protein_coding synonymous_variant LOW 1773A>G Glu591Glu
M0125384 CBFCNCDH_00003 2141 3 Oral 0.50 protein_coding synonymous_variant LOW 1389C>A Ile463Ile
M0125385 CBFCNCDH_00003 2888 3 Oral 0.50 protein_coding synonymous_variant LOW 642T>C Asn214Asn
M0125386 CBFCNCDH_00003 2942 3 Oral 0.50 protein_coding synonymous_variant LOW 588G>T Val196Val
M0125387 CBFCNCDH_00003 2971 3 Oral 0.50 protein_coding missense_variant MODERATE 559G>C Val187Leu
M0125388 CBFCNCDH_00003 3040 3 Oral 0.50 protein_coding missense_variant MODERATE 490G>C Val164Leu
M0125389 CBFCNCDH_00003 3041 3 Oral 0.50 protein_coding synonymous_variant LOW 489A>T Ala163Ala
M0125390 CBFCNCDH_00003 3434 3 Oral 0.50 protein_coding synonymous_variant LOW 96A>G Leu32Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term