Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2433
  Reference Plasmid   1111525849768046_bin.37__k141_24603
  Reference Plasmid Size   3117
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0125648 ENFDIHNJ_00001 40 7 Oral 0.88 protein_coding upstream_gene_variant MODIFIER -76G>A None
M0125649 ENFDIHNJ_00001 94 8 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -22G>A None
M0125650 ENFDIHNJ_00001 103 6 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -13G>A None
M0125651 ENFDIHNJ_00001 133 8 Oral 1.00 protein_coding synonymous_variant LOW 18T>A Val6Val
M0125652 ENFDIHNJ_00001 190 5 Oral 0.63 protein_coding synonymous_variant LOW 75C>T Asp25Asp
M0125653 ENFDIHNJ_00001 196 6 Oral 0.75 protein_coding synonymous_variant LOW 81G>A Leu27Leu
M0125654 ENFDIHNJ_00001 313 5 Oral 0.63 protein_coding synonymous_variant LOW 198C>T Pro66Pro
M0125655 ENFDIHNJ_00001 381 8 Oral 1.00 protein_coding missense_variant MODERATE 266C>A Thr89Asn
M0125656 ENFDIHNJ_00001 472 8 Oral 1.00 protein_coding synonymous_variant LOW 357T>C His119His
M0125657 ENFDIHNJ_00001 668 7 Oral 0.88 protein_coding missense_variant MODERATE 553G>C Ala185Pro
M0125658 ENFDIHNJ_00001 742 7 Oral 0.88 protein_coding synonymous_variant LOW 627C>T Asp209Asp
M0125659 ENFDIHNJ_00001 817 7 Oral 0.88 protein_coding synonymous_variant LOW 702A>G Lys234Lys
M0125660 ENFDIHNJ_00001 871 8 Oral 1.00 protein_coding synonymous_variant LOW 756T>C Tyr252Tyr
M0125661 ENFDIHNJ_00001 982 8 Oral 1.00 protein_coding synonymous_variant LOW 867T>C Gly289Gly
M0125662 ENFDIHNJ_00001 1069 3 Oral 0.38 protein_coding synonymous_variant LOW 954G>A Lys318Lys
M0125663 ENFDIHNJ_00001 1183 4 Oral 0.50 protein_coding synonymous_variant LOW 1068C>T Ile356Ile
M0125664 ENFDIHNJ_00001 1522 7 Oral 0.88 protein_coding synonymous_variant LOW 1407A>G Val469Val
M0125665 ENFDIHNJ_00003 1678 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -570G>A None
M0125666 ENFDIHNJ_00003 2457 6 Oral 0.75 protein_coding synonymous_variant LOW 210A>G Leu70Leu
M0125667 ENFDIHNJ_00003 2607 4 Oral 0.50 protein_coding synonymous_variant LOW 360G>A Leu120Leu
M0125668 ENFDIHNJ_00003 2644 5 Oral 0.63 protein_coding missense_variant MODERATE 397A>G Ile133Val
M0125669 ENFDIHNJ_00003 2646 6 Oral 0.75 protein_coding synonymous_variant LOW 399T>A Ile133Ile
M0125670 ENFDIHNJ_00003 2649 6 Oral 0.75 protein_coding synonymous_variant LOW 402A>G Leu134Leu
M0125671 ENFDIHNJ_00003 2694 4 Oral 0.50 protein_coding synonymous_variant LOW 447A>G Gln149Gln
M0125672 ENFDIHNJ_00001 89 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -27C>A None
M0125673 ENFDIHNJ_00001 436 4 Oral 0.50 protein_coding synonymous_variant LOW 321G>A Gln107Gln
M0125674 ENFDIHNJ_00001 658 4 Oral 0.50 protein_coding synonymous_variant LOW 543A>T Thr181Thr
M0125675 ENFDIHNJ_00001 667 4 Oral 0.50 protein_coding synonymous_variant LOW 552C>A Gly184Gly
M0125676 ENFDIHNJ_00001 925 7 Oral 0.88 protein_coding synonymous_variant LOW 810A>G Ser270Ser
M0125677 ENFDIHNJ_00001 1294 3 Oral 0.38 protein_coding synonymous_variant LOW 1179C>A Pro393Pro
M0125678 ENFDIHNJ_00001 1318 5 Oral 0.63 protein_coding synonymous_variant LOW 1203T>C Tyr401Tyr
M0125679 ENFDIHNJ_00001 1444 6 Oral 0.75 protein_coding synonymous_variant LOW 1329C>T Thr443Thr
M0125680 ENFDIHNJ_00002 1778 3 Oral 0.38 protein_coding synonymous_variant LOW 294C>T Phe98Phe
M0125681 ENFDIHNJ_00002 1814 3 Oral 0.38 protein_coding synonymous_variant LOW 258A>T Val86Val
M0125682 ENFDIHNJ_00002 1827 4 Oral 0.50 protein_coding missense_variant MODERATE 245T>C Met82Thr
M0125683 ENFDIHNJ_00002 1892 3 Oral 0.38 protein_coding synonymous_variant LOW 180C>T Gly60Gly
M0125684 ENFDIHNJ_00002 2141 4 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -70C>T None
M0125685 ENFDIHNJ_00002 2164 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -93A>G None
M0125686 ENFDIHNJ_00003 2517 5 Oral 0.63 protein_coding synonymous_variant LOW 270A>G Leu90Leu
M0125687 ENFDIHNJ_00002 2737 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -666T>A None
M0125688 ENFDIHNJ_00002 2750 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -679T>C None
M0125689 ENFDIHNJ_00001 577 3 Oral 0.38 protein_coding synonymous_variant LOW 462A>G Pro154Pro
M0125690 ENFDIHNJ_00001 1093 5 Oral 0.63 protein_coding synonymous_variant LOW 978T>C Gly326Gly
M0125691 ENFDIHNJ_00001 1135 4 Oral 0.50 protein_coding synonymous_variant LOW 1020T>C His340His
M0125692 ENFDIHNJ_00001 1276 3 Oral 0.38 protein_coding synonymous_variant LOW 1161C>T Asn387Asn
M0125693 ENFDIHNJ_00003 2388 4 Oral 0.50 protein_coding synonymous_variant LOW 141A>G Lys47Lys
M0125694 ENFDIHNJ_00002 2243 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -172T>C None
M0125695 ENFDIHNJ_00002 2244 3 Oral 0.38 protein_coding upstream_gene_variant MODIFIER -173A>G None
M0125696 ENFDIHNJ_00001 601 4 Oral 0.50 protein_coding synonymous_variant LOW 486G>A Lys162Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term