Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2439
  Reference Plasmid   1111525849768046_bin.37__k141_34689
  Reference Plasmid Size   4618
  Reference Plasmid GC Content   0.35
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0125935 KLPDEMAB_00001 1190 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1753C>G None
M0125936 KLPDEMAB_00001 1238 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1705G>T None
M0125937 KLPDEMAB_00001 1343 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1600T>A None
M0125938 KLPDEMAB_00001 1382 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1561A>G None
M0125939 KLPDEMAB_00001 1460 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -1483T>A None
M0125940 KLPDEMAB_00001 1523 6 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -1420T>C None
M0125941 KLPDEMAB_00001 1884 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1059T>G None
M0125942 KLPDEMAB_00001 1966 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -977A>G None
M0125943 KLPDEMAB_00001 1994 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -949T>C None
M0125944 KLPDEMAB_00001 2009 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -934T>G None
M0125945 KLPDEMAB_00001 2024 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -919A>G None
M0125946 KLPDEMAB_00001 2039 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -904A>G None
M0125947 KLPDEMAB_00001 2102 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -841G>A None
M0125948 KLPDEMAB_00001 2120 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -823T>C None
M0125949 KLPDEMAB_00001 2123 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -820C>T None
M0125950 KLPDEMAB_00001 2135 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -808C>A None
M0125951 KLPDEMAB_00001 2208 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -735A>G None
M0125952 KLPDEMAB_00001 2230 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -713A>G None
M0125953 KLPDEMAB_00001 2231 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -712A>G None
M0125954 KLPDEMAB_00001 2240 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -703G>A None
M0125955 KLPDEMAB_00001 2252 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -691A>T None
M0125956 KLPDEMAB_00001 2254 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -689G>T None
M0125957 KLPDEMAB_00001 2282 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -661G>T None
M0125958 KLPDEMAB_00001 2318 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -625A>G None
M0125959 KLPDEMAB_00001 2552 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -391A>G None
M0125960 KLPDEMAB_00001 98 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2845G>A None
M0125961 KLPDEMAB_00001 283 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2660T>C None
M0125962 KLPDEMAB_00001 323 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2620A>G None
M0125963 KLPDEMAB_00001 353 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2590G>A None
M0125964 KLPDEMAB_00001 368 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2575T>G None
M0125965 KLPDEMAB_00001 533 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2410T>C None
M0125966 KLPDEMAB_00001 545 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2398G>T None
M0125967 KLPDEMAB_00001 584 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2359C>T None
M0125968 KLPDEMAB_00001 779 5 Oral 0.83 protein_coding upstream_gene_variant MODIFIER -2164T>A None
M0125969 KLPDEMAB_00001 839 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2104A>G None
M0125970 KLPDEMAB_00001 905 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2038G>A None
M0125971 KLPDEMAB_00001 920 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2023A>G None
M0125972 KLPDEMAB_00001 926 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2017A>T None
M0125973 KLPDEMAB_00001 932 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2011G>T None
M0125974 KLPDEMAB_00001 938 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2005G>A None
M0125975 KLPDEMAB_00001 971 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1972T>C None
M0125976 KLPDEMAB_00001 986 4 Oral 0.67 protein_coding upstream_gene_variant MODIFIER -1957A>G None
M0125977 KLPDEMAB_00001 1003 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1940C>T None
M0125978 KLPDEMAB_00001 164 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -2779G>T None
M0125979 KLPDEMAB_00001 1249 3 Oral 0.50 protein_coding upstream_gene_variant MODIFIER -1694A>G None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term