Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2442
  Reference Plasmid   1111525849768046_bin.37__k141_36538
  Reference Plasmid Size   7826
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0126317 FDJLHFJK_00002 1562 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -131A>T None
M0126318 FDJLHFJK_00002 1570 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -123T>C None
M0126319 FDJLHFJK_00002 1571 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -122A>T None
M0126320 FDJLHFJK_00002 1752 4 Oral 0.36 protein_coding synonymous_variant LOW 60A>G Gln20Gln
M0126321 FDJLHFJK_00002 2016 4 Oral 0.36 protein_coding missense_variant MODERATE 324A>T Glu108Asp
M0126322 FDJLHFJK_00002 2034 5 Oral 0.45 protein_coding synonymous_variant LOW 342A>T Ala114Ala
M0126323 FDJLHFJK_00002 2112 5 Oral 0.45 protein_coding synonymous_variant LOW 420T>C Asp140Asp
M0126324 FDJLHFJK_00002 2466 3 Oral 0.27 protein_coding synonymous_variant LOW 774T>C Gly258Gly
M0126325 FDJLHFJK_00002 2727 6 Oral 0.55 protein_coding synonymous_variant LOW 1035A>T Ala345Ala
M0126326 FDJLHFJK_00002 2835 3 Oral 0.27 protein_coding synonymous_variant LOW 1143A>G Lys381Lys
M0126327 FDJLHFJK_00002 2862 5 Oral 0.45 protein_coding synonymous_variant LOW 1170T>C Tyr390Tyr
M0126328 FDJLHFJK_00002 2871 4 Oral 0.36 protein_coding synonymous_variant LOW 1179G>A Pro393Pro
M0126329 FDJLHFJK_00002 2958 4 Oral 0.36 protein_coding synonymous_variant LOW 1266T>C Cys422Cys
M0126330 FDJLHFJK_00002 3003 6 Oral 0.55 protein_coding synonymous_variant LOW 1311A>T Ala437Ala
M0126331 FDJLHFJK_00002 3033 3 Oral 0.27 protein_coding synonymous_variant LOW 1341A>T Ala447Ala
M0126332 FDJLHFJK_00002 3183 6 Oral 0.55 protein_coding synonymous_variant LOW 1491G>A Leu497Leu
M0126333 FDJLHFJK_00003 5641 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -286A>T None
M0126334 FDJLHFJK_00003 5660 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -305G>A None
M0126335 FDJLHFJK_00003 5664 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -309T>C None
M0126336 FDJLHFJK_00003 5701 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -346A>T None
M0126337 FDJLHFJK_00003 5709 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -354T>C None
M0126338 FDJLHFJK_00004 6263 4 Oral 0.36 protein_coding synonymous_variant LOW 309T>C Ser103Ser
M0126339 FDJLHFJK_00004 6341 3 Oral 0.27 protein_coding missense_variant MODERATE 387C>G Asp129Glu
M0126340 FDJLHFJK_00004 6344 4 Oral 0.36 protein_coding synonymous_variant LOW 390G>A Gly130Gly
M0126341 FDJLHFJK_00004 6540 3 Oral 0.27 protein_coding missense_variant MODERATE 586G>A Gly196Arg
M0126342 FDJLHFJK_00003 6735 4 Oral 0.36 protein_coding upstream_gene_variant MODIFIER -1380A>G None
M0126343 FDJLHFJK_00003 6742 4 Oral 0.36 protein_coding upstream_gene_variant MODIFIER -1387T>G None
M0126344 FDJLHFJK_00003 6743 4 Oral 0.36 protein_coding upstream_gene_variant MODIFIER -1388A>C None
M0126345 FDJLHFJK_00003 6863 3 Oral 0.27 protein_coding upstream_gene_variant MODIFIER -1508A>G None
M0126346 FDJLHFJK_00005 6902 4 Oral 0.36 protein_coding synonymous_variant LOW 21T>C Thr7Thr
M0126347 FDJLHFJK_00005 7130 4 Oral 0.36 protein_coding synonymous_variant LOW 249T>C Pro83Pro
M0126348 FDJLHFJK_00005 7164 4 Oral 0.36 protein_coding missense_variant MODERATE 283A>C Lys95Gln
M0126349 FDJLHFJK_00005 7181 3 Oral 0.27 protein_coding synonymous_variant LOW 300T>C Phe100Phe
M0126350 FDJLHFJK_00005 7184 3 Oral 0.27 protein_coding synonymous_variant LOW 303C>T Leu101Leu
M0126351 FDJLHFJK_00005 7250 4 Oral 0.36 protein_coding synonymous_variant LOW 369T>C Asn123Asn
M0126352 FDJLHFJK_00005 7334 4 Oral 0.36 protein_coding synonymous_variant LOW 453T>C Asp151Asp
M0126353 FDJLHFJK_00005 7340 3 Oral 0.27 protein_coding synonymous_variant LOW 459A>T Ala153Ala
M0126354 FDJLHFJK_00005 7343 3 Oral 0.27 protein_coding synonymous_variant LOW 462T>C Ala154Ala
M0126355 FDJLHFJK_00005 7604 3 Oral 0.27 protein_coding synonymous_variant LOW 723A>T Ala241Ala
M0126356 FDJLHFJK_00001 1443 5 Oral 0.45 protein_coding synonymous_variant LOW 1356G>A Gly452Gly
M0126357 FDJLHFJK_00001 1449 5 Oral 0.45 protein_coding synonymous_variant LOW 1362T>C Ser454Ser
M0126358 FDJLHFJK_00002 1971 5 Oral 0.45 protein_coding synonymous_variant LOW 279T>C Asp93Asp
M0126359 FDJLHFJK_00002 2751 3 Oral 0.27 protein_coding synonymous_variant LOW 1059C>T Phe353Phe
M0126360 FDJLHFJK_00002 2913 3 Oral 0.27 protein_coding synonymous_variant LOW 1221A>T Gly407Gly
M0126361 FDJLHFJK_00004 3722 4 Oral 0.36 protein_coding upstream_gene_variant MODIFIER -2233T>A None
M0126362 FDJLHFJK_00003 4033 4 Oral 0.36 protein_coding synonymous_variant LOW 1323T>C Asn441Asn
M0126363 FDJLHFJK_00003 4162 4 Oral 0.36 protein_coding synonymous_variant LOW 1194T>A Pro398Pro
M0126364 FDJLHFJK_00003 4228 4 Oral 0.36 protein_coding synonymous_variant LOW 1128T>A Thr376Thr
M0126365 FDJLHFJK_00003 4390 3 Oral 0.27 protein_coding synonymous_variant LOW 966T>C Asp322Asp
M0126366 FDJLHFJK_00003 4468 3 Oral 0.27 protein_coding synonymous_variant LOW 888C>T Asp296Asp
M0126367 FDJLHFJK_00003 5083 4 Oral 0.36 protein_coding synonymous_variant LOW 273C>T His91His
M0126368 FDJLHFJK_00003 5376 4 Oral 0.36 protein_coding upstream_gene_variant MODIFIER -21A>T None
M0126369 FDJLHFJK_00004 6115 3 Oral 0.27 protein_coding missense_variant MODERATE 161C>A Ala54Glu
M0126370 FDJLHFJK_00001 29 6 Oral 0.55 protein_coding upstream_gene_variant MODIFIER -59T>A None
M0126371 FDJLHFJK_00001 215 4 Oral 0.36 protein_coding missense_variant MODERATE 128C>T Ala43Val
M0126372 FDJLHFJK_00001 273 6 Oral 0.55 protein_coding synonymous_variant LOW 186A>G Glu62Glu
M0126373 FDJLHFJK_00001 485 6 Oral 0.55 protein_coding missense_variant MODERATE 398G>A Arg133Lys
M0126374 FDJLHFJK_00001 576 3 Oral 0.27 protein_coding synonymous_variant LOW 489C>T Ser163Ser
M0126375 FDJLHFJK_00001 651 3 Oral 0.27 protein_coding synonymous_variant LOW 564G>A Leu188Leu
M0126376 FDJLHFJK_00001 654 3 Oral 0.27 protein_coding synonymous_variant LOW 567T>C Ile189Ile
M0126377 FDJLHFJK_00001 747 5 Oral 0.45 protein_coding missense_variant MODERATE 660G>T Lys220Asn
M0126378 FDJLHFJK_00001 753 6 Oral 0.55 protein_coding synonymous_variant LOW 666T>C Arg222Arg
M0126379 FDJLHFJK_00001 756 5 Oral 0.45 protein_coding synonymous_variant LOW 669T>C Pro223Pro
M0126380 FDJLHFJK_00001 896 5 Oral 0.45 protein_coding missense_variant MODERATE 809T>C Val270Ala
M0126381 FDJLHFJK_00001 909 6 Oral 0.55 protein_coding synonymous_variant LOW 822T>C Asn274Asn
M0126382 FDJLHFJK_00001 910 6 Oral 0.55 protein_coding missense_variant MODERATE 823A>G Thr275Ala
M0126383 FDJLHFJK_00001 915 5 Oral 0.45 protein_coding synonymous_variant LOW 828A>G Glu276Glu
M0126384 FDJLHFJK_00001 1294 6 Oral 0.55 protein_coding missense_variant MODERATE 1207A>G Thr403Ala
M0126385 FDJLHFJK_00001 1317 5 Oral 0.45 protein_coding missense_variant MODERATE 1230A>G Ile410Met
M0126386 FDJLHFJK_00001 102 3 Oral 0.27 protein_coding synonymous_variant LOW 15G>A Leu5Leu
M0126387 FDJLHFJK_00001 441 5 Oral 0.45 protein_coding synonymous_variant LOW 354T>A Leu118Leu
M0126388 FDJLHFJK_00001 628 3 Oral 0.27 protein_coding missense_variant MODERATE 541A>T Ser181Cys
M0126389 FDJLHFJK_00001 645 4 Oral 0.36 protein_coding synonymous_variant LOW 558T>C Arg186Arg
M0126390 FDJLHFJK_00001 1032 3 Oral 0.27 protein_coding synonymous_variant LOW 945C>T Asn315Asn
M0126391 FDJLHFJK_00001 1266 3 Oral 0.27 protein_coding synonymous_variant LOW 1179A>G Gln393Gln
M0126392 FDJLHFJK_00001 1412 3 Oral 0.27 protein_coding missense_variant MODERATE 1325G>C Gly442Ala
M0126393 FDJLHFJK_00002 2319 3 Oral 0.27 protein_coding synonymous_variant LOW 627C>T Phe209Phe
M0126394 FDJLHFJK_00002 2550 4 Oral 0.36 protein_coding synonymous_variant LOW 858C>T Asn286Asn
M0126395 FDJLHFJK_00003 4507 3 Oral 0.27 protein_coding synonymous_variant LOW 849T>C Tyr283Tyr
M0126396 FDJLHFJK_00003 5065 3 Oral 0.27 protein_coding synonymous_variant LOW 291A>T Ala97Ala
M0126397 FDJLHFJK_00001 1170 3 Oral 0.27 protein_coding synonymous_variant LOW 1083A>T Arg361Arg
M0126398 FDJLHFJK_00001 1179 3 Oral 0.27 protein_coding synonymous_variant LOW 1092G>A Ala364Ala
M0126399 FDJLHFJK_00001 1335 3 Oral 0.27 protein_coding synonymous_variant LOW 1248C>T Arg416Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
FDJLHFJK_00002 EFC71061.2|GH109 97.3 0 1 515 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term