Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2444
  Reference Plasmid   1111525849768046_bin.37__k141_38842
  Reference Plasmid Size   5860
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0126423 AOHJPMNM_00001 692 3 Oral 0.75 protein_coding synonymous_variant LOW 633A>G Lys211Lys
M0126424 AOHJPMNM_00001 864 3 Oral 0.75 protein_coding missense_variant MODERATE 805G>T Ala269Ser
M0126425 AOHJPMNM_00001 905 3 Oral 0.75 protein_coding synonymous_variant LOW 846T>C Asp282Asp
M0126426 AOHJPMNM_00001 989 3 Oral 0.75 protein_coding synonymous_variant LOW 930G>A Glu310Glu
M0126427 AOHJPMNM_00001 995 3 Oral 0.75 protein_coding missense_variant MODERATE 936A>C Glu312Asp
M0126428 AOHJPMNM_00001 998 3 Oral 0.75 protein_coding synonymous_variant LOW 939G>A Lys313Lys
M0126429 AOHJPMNM_00001 1004 3 Oral 0.75 protein_coding synonymous_variant LOW 945C>T Asn315Asn
M0126430 AOHJPMNM_00001 1376 3 Oral 0.75 protein_coding synonymous_variant LOW 1317A>T Ala439Ala
M0126431 AOHJPMNM_00001 1406 3 Oral 0.75 protein_coding synonymous_variant LOW 1347T>C Asp449Asp
M0126432 AOHJPMNM_00001 1427 3 Oral 0.75 protein_coding synonymous_variant LOW 1368T>A Thr456Thr
M0126433 AOHJPMNM_00001 1527 3 Oral 0.75 protein_coding missense_variant MODERATE 1468A>G Asn490Asp
M0126434 AOHJPMNM_00001 1559 3 Oral 0.75 protein_coding synonymous_variant LOW 1500A>G Val500Val
M0126435 AOHJPMNM_00001 1571 3 Oral 0.75 protein_coding synonymous_variant LOW 1512C>T Asn504Asn
M0126436 AOHJPMNM_00001 1658 3 Oral 0.75 protein_coding synonymous_variant LOW 1599T>C Asp533Asp
M0126437 AOHJPMNM_00001 1754 3 Oral 0.75 protein_coding synonymous_variant LOW 1695C>T Asp565Asp
M0126438 AOHJPMNM_00001 1949 3 Oral 0.75 protein_coding synonymous_variant LOW 1890G>A Gly630Gly
M0126439 AOHJPMNM_00001 2087 3 Oral 0.75 protein_coding synonymous_variant LOW 2028A>G Lys676Lys
M0126440 AOHJPMNM_00001 2106 3 Oral 0.75 protein_coding missense_variant MODERATE 2047T>G Ser683Ala
M0126441 AOHJPMNM_00001 2123 3 Oral 0.75 protein_coding synonymous_variant LOW 2064T>C Asp688Asp
M0126442 AOHJPMNM_00001 2174 3 Oral 0.75 protein_coding synonymous_variant LOW 2115T>C Gly705Gly
M0126443 AOHJPMNM_00001 2198 3 Oral 0.75 protein_coding synonymous_variant LOW 2139T>C Ser713Ser
M0126444 AOHJPMNM_00001 2906 3 Oral 0.75 protein_coding synonymous_variant LOW 2847T>A Ala949Ala
M0126445 AOHJPMNM_00002 3079 3 Oral 0.75 protein_coding synonymous_variant LOW 276T>C Ile92Ile
M0126446 AOHJPMNM_00002 3235 3 Oral 0.75 protein_coding synonymous_variant LOW 120G>A Ala40Ala
M0126447 AOHJPMNM_00003 3529 3 Oral 0.75 protein_coding synonymous_variant LOW 177T>C Ser59Ser
M0126448 AOHJPMNM_00003 3638 3 Oral 0.75 protein_coding stop_gained HIGH 68T>A Leu23*
M0126449 AOHJPMNM_00004 3842 3 Oral 0.75 protein_coding synonymous_variant LOW 51T>A Thr17Thr
M0126450 AOHJPMNM_00005 4391 3 Oral 0.75 protein_coding synonymous_variant LOW 36A>T Ala12Ala
M0126451 AOHJPMNM_00005 4694 3 Oral 0.75 protein_coding synonymous_variant LOW 339T>C Ala113Ala
M0126452 AOHJPMNM_00005 4710 3 Oral 0.75 protein_coding synonymous_variant LOW 355A>C Arg119Arg
M0126453 AOHJPMNM_00005 4781 3 Oral 0.75 protein_coding synonymous_variant LOW 426G>A Thr142Thr
M0126454 AOHJPMNM_00005 4787 3 Oral 0.75 protein_coding synonymous_variant LOW 432G>A Ser144Ser
M0126455 AOHJPMNM_00005 4904 3 Oral 0.75 protein_coding synonymous_variant LOW 549T>C Leu183Leu
M0126456 AOHJPMNM_00005 4967 3 Oral 0.75 protein_coding synonymous_variant LOW 612T>C Gly204Gly
M0126457 AOHJPMNM_00005 5102 3 Oral 0.75 protein_coding synonymous_variant LOW 747A>C Gly249Gly
M0126458 AOHJPMNM_00005 5207 3 Oral 0.75 protein_coding synonymous_variant LOW 852A>G Ser284Ser
M0126459 AOHJPMNM_00006 5304 3 Oral 0.75 protein_coding missense_variant MODERATE 186T>G Phe62Leu
M0126460 AOHJPMNM_00002 5490 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -2136T>A None
M0126461 AOHJPMNM_00001 38 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -22A>T None
M0126462 AOHJPMNM_00001 113 3 Oral 0.75 protein_coding synonymous_variant LOW 54T>C Thr18Thr
M0126463 AOHJPMNM_00001 131 3 Oral 0.75 protein_coding synonymous_variant LOW 72G>A Lys24Lys






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term