Annotation Categories of the Plasmid Cluster
Summary of the plasmid cluster
Basic Information about the Plasmid Cluster
Cluster Information |
Plasmid Cluster ID |
C2450 |
Reference Plasmid |
1111525849768046_bin.37__k141_43714 |
Reference Plasmid Size |
13110 |
Reference Plasmid GC Content |
0.37 |
Reference Plasmid Mobility Type |
non-mobilizable |
Mutation sites in the plasmid cluster
The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..
mutid |
gname |
pos |
count |
tissue |
frequnt |
biotype |
consequence |
impact |
nucchange |
aachange |
M0126980 |
MBDAEDNM_00004 |
4200 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
456T>C |
Ala152Ala |
M0126981 |
MBDAEDNM_00004 |
4203 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
453T>C |
Asp151Asp |
M0126982 |
MBDAEDNM_00004 |
4212 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
444C>T |
Ala148Ala |
M0126983 |
MBDAEDNM_00004 |
4218 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
438C>T |
His146His |
M0126984 |
MBDAEDNM_00004 |
4266 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
390A>G |
Gln130Gln |
M0126985 |
MBDAEDNM_00004 |
4425 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
231T>A |
Pro77Pro |
M0126986 |
MBDAEDNM_00004 |
4710 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-55G>A |
None |
M0126987 |
MBDAEDNM_00004 |
4713 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-58A>T |
None |
M0126988 |
MBDAEDNM_00004 |
4799 |
6 |
Oral |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-144C>T |
None |
M0126989 |
MBDAEDNM_00005 |
4871 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
42G>A |
Ala14Ala |
M0126990 |
MBDAEDNM_00005 |
4889 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
60A>T |
Thr20Thr |
M0126991 |
MBDAEDNM_00005 |
5051 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
222T>C |
Arg74Arg |
M0126992 |
MBDAEDNM_00005 |
5066 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
237T>C |
His79His |
M0126993 |
MBDAEDNM_00005 |
5261 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
432G>A |
Gly144Gly |
M0126994 |
MBDAEDNM_00005 |
5273 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
444T>C |
Gly148Gly |
M0126995 |
MBDAEDNM_00005 |
5318 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
489T>C |
Ile163Ile |
M0126996 |
MBDAEDNM_00005 |
5387 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
558G>A |
Gly186Gly |
M0126997 |
MBDAEDNM_00005 |
5393 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
564C>G |
Val188Val |
M0126998 |
MBDAEDNM_00005 |
5513 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
684C>T |
Asp228Asp |
M0126999 |
MBDAEDNM_00005 |
5600 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
771T>C |
Ser257Ser |
M0127000 |
MBDAEDNM_00005 |
5642 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
813G>A |
Glu271Glu |
M0127001 |
MBDAEDNM_00005 |
5681 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
852T>C |
His284His |
M0127002 |
MBDAEDNM_00005 |
5711 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
882A>G |
Arg294Arg |
M0127003 |
MBDAEDNM_00005 |
5723 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
894G>A |
Lys298Lys |
M0127004 |
MBDAEDNM_00005 |
5955 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
1126A>G |
Ile376Val |
M0127005 |
MBDAEDNM_00005 |
5972 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
1143G>A |
Ser381Ser |
M0127006 |
MBDAEDNM_00005 |
5993 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1164A>G |
Lys388Lys |
M0127007 |
MBDAEDNM_00005 |
6011 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1182C>T |
Val394Val |
M0127008 |
MBDAEDNM_00005 |
6026 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1197T>C |
Ile399Ile |
M0127009 |
MBDAEDNM_00005 |
6065 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1236T>C |
Arg412Arg |
M0127010 |
MBDAEDNM_00005 |
6068 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1239T>A |
Leu413Leu |
M0127011 |
MBDAEDNM_00005 |
6134 |
7 |
Oral |
0.78 |
protein_coding |
synonymous_variant |
LOW |
1305C>T |
Ala435Ala |
M0127012 |
MBDAEDNM_00005 |
6149 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1320A>T |
Leu440Leu |
M0127013 |
MBDAEDNM_00007 |
8804 |
7 |
Oral |
0.78 |
protein_coding |
missense_variant |
MODERATE |
703G>A |
Ala235Thr |
M0127014 |
MBDAEDNM_00004 |
4281 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
375C>T |
His125His |
M0127015 |
MBDAEDNM_00004 |
4551 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
105G>A |
Ser35Ser |
M0127016 |
MBDAEDNM_00004 |
4563 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
93A>G |
Val31Val |
M0127017 |
MBDAEDNM_00005 |
5106 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
277T>C |
Leu93Leu |
M0127018 |
MBDAEDNM_00005 |
5171 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
342C>T |
Ile114Ile |
M0127019 |
MBDAEDNM_00005 |
5354 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
525A>C |
Ala175Ala |
M0127020 |
MBDAEDNM_00005 |
5357 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
528C>T |
Asp176Asp |
M0127021 |
MBDAEDNM_00005 |
5378 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
549A>T |
Ile183Ile |
M0127022 |
MBDAEDNM_00005 |
5510 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
681T>C |
His227His |
M0127023 |
MBDAEDNM_00005 |
5546 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
717C>T |
Gly239Gly |
M0127024 |
MBDAEDNM_00005 |
5558 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
729T>C |
Gly243Gly |
M0127025 |
MBDAEDNM_00005 |
5564 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
735T>A |
Gly245Gly |
M0127026 |
MBDAEDNM_00005 |
5693 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
864T>C |
Phe288Phe |
M0127027 |
MBDAEDNM_00005 |
5702 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
873A>T |
Glu291Asp |
M0127028 |
MBDAEDNM_00005 |
5732 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
903A>G |
Val301Val |
M0127029 |
MBDAEDNM_00005 |
5777 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
948A>C |
Ile316Ile |
M0127030 |
MBDAEDNM_00005 |
5823 |
5 |
Oral |
0.56 |
protein_coding |
missense_variant |
MODERATE |
994A>G |
Ile332Val |
M0127031 |
MBDAEDNM_00005 |
5837 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1008T>C |
Asp336Asp |
M0127032 |
MBDAEDNM_00005 |
5843 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
1014T>A |
Gly338Gly |
M0127033 |
MBDAEDNM_00005 |
5885 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1056A>G |
Leu352Leu |
M0127034 |
MBDAEDNM_00005 |
5903 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1074T>A |
Pro358Pro |
M0127035 |
MBDAEDNM_00005 |
5927 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1098A>G |
Lys366Lys |
M0127036 |
MBDAEDNM_00005 |
6002 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1173A>G |
Glu391Glu |
M0127037 |
MBDAEDNM_00005 |
6098 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1269T>C |
Asn423Asn |
M0127038 |
MBDAEDNM_00005 |
6119 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1290C>T |
Gly430Gly |
M0127039 |
MBDAEDNM_00005 |
6170 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1341G>A |
Val447Val |
M0127040 |
MBDAEDNM_00005 |
6187 |
6 |
Oral |
0.67 |
protein_coding |
missense_variant |
MODERATE |
1358C>A |
Pro453Gln |
M0127041 |
MBDAEDNM_00005 |
6218 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1389C>T |
Gly463Gly |
M0127042 |
MBDAEDNM_00005 |
6262 |
3 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
1433G>A |
Ser478Asn |
M0127043 |
MBDAEDNM_00005 |
6317 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
1488T>A |
Val496Val |
M0127044 |
MBDAEDNM_00005 |
6374 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1545C>T |
Arg515Arg |
M0127045 |
MBDAEDNM_00004 |
6417 |
6 |
Oral |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1762A>G |
None |
M0127046 |
MBDAEDNM_00004 |
6483 |
5 |
Oral |
0.56 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1828G>A |
None |
M0127047 |
MBDAEDNM_00004 |
6526 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1871T>C |
None |
M0127048 |
MBDAEDNM_00004 |
6527 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1872A>G |
None |
M0127049 |
MBDAEDNM_00004 |
6534 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1879T>C |
None |
M0127050 |
MBDAEDNM_00004 |
6541 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1886A>G |
None |
M0127051 |
MBDAEDNM_00004 |
6542 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1887G>A |
None |
M0127052 |
MBDAEDNM_00004 |
6546 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1891G>A |
None |
M0127053 |
MBDAEDNM_00004 |
6563 |
6 |
Oral |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1908C>T |
None |
M0127054 |
MBDAEDNM_00004 |
6595 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1940G>A |
None |
M0127055 |
MBDAEDNM_00004 |
6626 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-1971T>A |
None |
M0127056 |
MBDAEDNM_00004 |
6719 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2064G>A |
None |
M0127057 |
MBDAEDNM_00004 |
6751 |
6 |
Oral |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2096T>C |
None |
M0127058 |
MBDAEDNM_00004 |
6770 |
6 |
Oral |
0.67 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-2115G>T |
None |
M0127059 |
MBDAEDNM_00006 |
6808 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
30G>A |
Arg10Arg |
M0127060 |
MBDAEDNM_00006 |
6826 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
48C>A |
Leu16Leu |
M0127061 |
MBDAEDNM_00006 |
6832 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
54G>A |
Ser18Ser |
M0127062 |
MBDAEDNM_00006 |
6874 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
96G>A |
Glu32Glu |
M0127063 |
MBDAEDNM_00006 |
6877 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
99T>C |
Pro33Pro |
M0127064 |
MBDAEDNM_00006 |
6886 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
108C>T |
Arg36Arg |
M0127065 |
MBDAEDNM_00006 |
6892 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
114A>C |
Ile38Ile |
M0127066 |
MBDAEDNM_00006 |
6895 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
117A>C |
Ser39Ser |
M0127067 |
MBDAEDNM_00006 |
6910 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
132G>A |
Ala44Ala |
M0127068 |
MBDAEDNM_00006 |
6928 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
150A>G |
Lys50Lys |
M0127069 |
MBDAEDNM_00006 |
6959 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
181C>T |
Leu61Leu |
M0127070 |
MBDAEDNM_00006 |
6967 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
189T>C |
Thr63Thr |
M0127071 |
MBDAEDNM_00006 |
6979 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
201C>T |
Leu67Leu |
M0127072 |
MBDAEDNM_00006 |
6982 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
204T>A |
Ile68Ile |
M0127073 |
MBDAEDNM_00006 |
6985 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
207A>C |
Thr69Thr |
M0127074 |
MBDAEDNM_00006 |
6988 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
210C>T |
Asp70Asp |
M0127075 |
MBDAEDNM_00006 |
6997 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
219C>T |
Cys73Cys |
M0127076 |
MBDAEDNM_00006 |
7048 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
270T>A |
Thr90Thr |
M0127077 |
MBDAEDNM_00006 |
7075 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
297G>C |
Thr99Thr |
M0127078 |
MBDAEDNM_00006 |
7090 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
312A>G |
Lys104Lys |
M0127079 |
MBDAEDNM_00006 |
7156 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
378T>A |
Ala126Ala |
M0127080 |
MBDAEDNM_00006 |
7186 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
408C>T |
Asp136Asp |
M0127081 |
MBDAEDNM_00006 |
7192 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
414T>C |
Pro138Pro |
M0127082 |
MBDAEDNM_00006 |
7193 |
6 |
Oral |
0.67 |
protein_coding |
missense_variant |
MODERATE |
415G>A |
Val139Ile |
M0127083 |
MBDAEDNM_00006 |
7218 |
6 |
Oral |
0.67 |
protein_coding |
missense_variant |
MODERATE |
440G>A |
Ser147Asn |
M0127084 |
MBDAEDNM_00006 |
7219 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
441T>C |
Ser147Ser |
M0127085 |
MBDAEDNM_00006 |
7246 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
468C>T |
Thr156Thr |
M0127086 |
MBDAEDNM_00006 |
7274 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
496T>A |
Ser166Thr |
M0127087 |
MBDAEDNM_00006 |
7342 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
564A>C |
Ala188Ala |
M0127088 |
MBDAEDNM_00006 |
7366 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
588T>C |
Cys196Cys |
M0127089 |
MBDAEDNM_00006 |
7375 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
597C>T |
Phe199Phe |
M0127090 |
MBDAEDNM_00006 |
7438 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
660T>C |
Ala220Ala |
M0127091 |
MBDAEDNM_00007 |
8533 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
432G>A |
Leu144Leu |
M0127092 |
MBDAEDNM_00007 |
8536 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
435C>T |
Ser145Ser |
M0127093 |
MBDAEDNM_00007 |
8560 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
459T>A |
Ile153Ile |
M0127094 |
MBDAEDNM_00007 |
8563 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
462C>T |
Gly154Gly |
M0127095 |
MBDAEDNM_00007 |
8731 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
630T>C |
Arg210Arg |
M0127096 |
MBDAEDNM_00007 |
8803 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
702G>A |
Lys234Lys |
M0127097 |
MBDAEDNM_00007 |
8875 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
774A>T |
Ala258Ala |
M0127098 |
MBDAEDNM_00007 |
8896 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
795A>G |
Glu265Glu |
M0127099 |
MBDAEDNM_00007 |
8932 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
831G>A |
Lys277Lys |
M0127100 |
MBDAEDNM_00007 |
8959 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
858T>A |
Ser286Ser |
M0127101 |
MBDAEDNM_00007 |
9022 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
921T>C |
Thr307Thr |
M0127102 |
MBDAEDNM_00008 |
9346 |
6 |
Oral |
0.67 |
protein_coding |
synonymous_variant |
LOW |
93A>C |
Ile31Ile |
M0127103 |
MBDAEDNM_00008 |
9382 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
129T>A |
Val43Val |
M0127104 |
MBDAEDNM_00008 |
9589 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
336C>T |
Tyr112Tyr |
M0127105 |
MBDAEDNM_00008 |
9808 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
555A>G |
Ala185Ala |
M0127106 |
MBDAEDNM_00008 |
9817 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
564T>A |
Ala188Ala |
M0127107 |
MBDAEDNM_00008 |
9838 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
585T>C |
Asn195Asn |
M0127108 |
MBDAEDNM_00008 |
9916 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
663G>A |
Pro221Pro |
M0127109 |
MBDAEDNM_00009 |
10097 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-61A>G |
None |
M0127110 |
MBDAEDNM_00009 |
10100 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-58A>G |
None |
M0127111 |
MBDAEDNM_00009 |
10441 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
284G>C |
Gly95Ala |
M0127112 |
MBDAEDNM_00009 |
10856 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
699C>T |
Cys233Cys |
M0127113 |
MBDAEDNM_00009 |
10889 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
732G>T |
Arg244Ser |
M0127114 |
MBDAEDNM_00009 |
10892 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
735G>A |
Ala245Ala |
M0127115 |
MBDAEDNM_00009 |
10955 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
798A>T |
Ala266Ala |
M0127116 |
MBDAEDNM_00009 |
11051 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
894G>T |
Ser298Ser |
M0127117 |
MBDAEDNM_00009 |
11123 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
966T>C |
Asp322Asp |
M0127118 |
MBDAEDNM_00009 |
11126 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
969T>A |
Leu323Leu |
M0127119 |
MBDAEDNM_00009 |
11132 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
975A>G |
Arg325Arg |
M0127120 |
MBDAEDNM_00009 |
11261 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1104T>C |
Asn368Asn |
M0127121 |
MBDAEDNM_00009 |
11270 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1113A>G |
Ala371Ala |
M0127122 |
MBDAEDNM_00009 |
11331 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1174T>C |
Leu392Leu |
M0127123 |
MBDAEDNM_00009 |
11357 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1200T>C |
Ala400Ala |
M0127124 |
MBDAEDNM_00009 |
11393 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1236A>T |
Pro412Pro |
M0127125 |
MBDAEDNM_00009 |
11400 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1243C>A |
Arg415Arg |
M0127126 |
MBDAEDNM_00009 |
11408 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1251C>T |
Thr417Thr |
M0127127 |
MBDAEDNM_00010 |
11506 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-73C>T |
None |
M0127128 |
MBDAEDNM_00010 |
11725 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
147C>T |
Tyr49Tyr |
M0127129 |
MBDAEDNM_00010 |
11728 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
150T>C |
Thr50Thr |
M0127130 |
MBDAEDNM_00010 |
11755 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
177C>T |
Tyr59Tyr |
M0127131 |
MBDAEDNM_00010 |
11758 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
180A>G |
Ser60Ser |
M0127132 |
MBDAEDNM_00010 |
11759 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
181G>A |
Gly61Ser |
M0127133 |
MBDAEDNM_00010 |
11780 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
202C>T |
Leu68Leu |
M0127134 |
MBDAEDNM_00010 |
11794 |
3 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
216G>A |
Met72Ile |
M0127135 |
MBDAEDNM_00010 |
11824 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
246C>T |
His82His |
M0127136 |
MBDAEDNM_00010 |
11836 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
258C>T |
Asp86Asp |
M0127137 |
MBDAEDNM_00010 |
11848 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
270A>G |
Gly90Gly |
M0127138 |
MBDAEDNM_00010 |
12106 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
528T>C |
Gly176Gly |
M0127139 |
MBDAEDNM_00010 |
12133 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
555C>A |
Gly185Gly |
M0127140 |
MBDAEDNM_00010 |
12163 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
585T>C |
Asn195Asn |
M0127141 |
MBDAEDNM_00010 |
12199 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
621C>T |
Pro207Pro |
M0127142 |
MBDAEDNM_00010 |
12235 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
657T>C |
Thr219Thr |
M0127143 |
MBDAEDNM_00010 |
12244 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
666G>A |
Lys222Lys |
M0127144 |
MBDAEDNM_00010 |
12272 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
694C>T |
Leu232Phe |
M0127145 |
MBDAEDNM_00010 |
12283 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
705G>T |
Gly235Gly |
M0127146 |
MBDAEDNM_00010 |
12295 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
717G>A |
Lys239Lys |
M0127147 |
MBDAEDNM_00010 |
12382 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
804C>A |
Thr268Thr |
M0127148 |
MBDAEDNM_00010 |
12463 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
885A>T |
Gly295Gly |
M0127149 |
MBDAEDNM_00010 |
12510 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
932T>C |
Val311Ala |
M0127150 |
MBDAEDNM_00010 |
12706 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1128C>T |
Gly376Gly |
M0127151 |
MBDAEDNM_00004 |
4479 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
177A>G |
Lys59Lys |
M0127152 |
MBDAEDNM_00004 |
4557 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
99T>G |
Thr33Thr |
M0127153 |
MBDAEDNM_00004 |
4605 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
51C>T |
Ser17Ser |
M0127154 |
MBDAEDNM_00005 |
5468 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
639C>T |
Asp213Asp |
M0127155 |
MBDAEDNM_00005 |
5474 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
645C>T |
Pro215Pro |
M0127156 |
MBDAEDNM_00005 |
5525 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
696G>A |
Val232Val |
M0127157 |
MBDAEDNM_00005 |
5828 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
999T>A |
Ile333Ile |
M0127158 |
MBDAEDNM_00006 |
7312 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
534C>T |
Asp178Asp |
M0127159 |
MBDAEDNM_00006 |
7313 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
535C>T |
Leu179Leu |
M0127160 |
MBDAEDNM_00006 |
7324 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
546T>G |
Thr182Thr |
M0127161 |
MBDAEDNM_00006 |
7355 |
3 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
577G>A |
Ala193Thr |
M0127162 |
MBDAEDNM_00006 |
7450 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
672A>G |
Gly224Gly |
M0127163 |
MBDAEDNM_00006 |
7456 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
678T>G |
Thr226Thr |
M0127164 |
MBDAEDNM_00006 |
7480 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
702T>C |
Arg234Arg |
M0127165 |
MBDAEDNM_00006 |
7495 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
717C>A |
Ala239Ala |
M0127166 |
MBDAEDNM_00006 |
7522 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
744A>G |
Val248Val |
M0127167 |
MBDAEDNM_00006 |
7612 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
834A>G |
Gln278Gln |
M0127168 |
MBDAEDNM_00006 |
7651 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
873G>A |
Lys291Lys |
M0127169 |
MBDAEDNM_00006 |
7666 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
888T>C |
Cys296Cys |
M0127170 |
MBDAEDNM_00006 |
7705 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
927C>T |
Asn309Asn |
M0127171 |
MBDAEDNM_00006 |
7723 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
945T>C |
Cys315Cys |
M0127172 |
MBDAEDNM_00006 |
7724 |
3 |
Oral |
0.33 |
protein_coding |
missense_variant |
MODERATE |
946C>T |
His316Tyr |
M0127173 |
MBDAEDNM_00006 |
7750 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
972A>G |
Leu324Leu |
M0127174 |
MBDAEDNM_00006 |
7756 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
978A>G |
Lys326Lys |
M0127175 |
MBDAEDNM_00006 |
7813 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1035G>A |
Glu345Glu |
M0127176 |
MBDAEDNM_00006 |
7831 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
1053G>A |
Pro351Pro |
M0127177 |
MBDAEDNM_00006 |
7843 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
1065A>G |
Val355Val |
M0127178 |
MBDAEDNM_00006 |
7873 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
1095A>G |
Glu365Glu |
M0127179 |
MBDAEDNM_00006 |
7876 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1098G>A |
Leu366Leu |
M0127180 |
MBDAEDNM_00004 |
7984 |
4 |
Oral |
0.44 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3329G>T |
None |
M0127181 |
MBDAEDNM_00004 |
7994 |
3 |
Oral |
0.33 |
protein_coding |
upstream_gene_variant |
MODIFIER |
-3339A>G |
None |
M0127182 |
MBDAEDNM_00005 |
6344 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1515C>T |
Tyr505Tyr |
M0127183 |
MBDAEDNM_00007 |
8254 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
153C>T |
Thr51Thr |
M0127184 |
MBDAEDNM_00007 |
8377 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
276A>C |
Thr92Thr |
M0127185 |
MBDAEDNM_00007 |
8782 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
681A>G |
Leu227Leu |
M0127186 |
MBDAEDNM_00007 |
8944 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
843C>T |
Gly281Gly |
M0127187 |
MBDAEDNM_00007 |
9064 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
963T>G |
Val321Val |
M0127188 |
MBDAEDNM_00007 |
9067 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
966C>T |
Gly322Gly |
M0127189 |
MBDAEDNM_00007 |
9076 |
5 |
Oral |
0.56 |
protein_coding |
synonymous_variant |
LOW |
975T>A |
Val325Val |
M0127190 |
MBDAEDNM_00008 |
9281 |
4 |
Oral |
0.44 |
protein_coding |
missense_variant |
MODERATE |
28A>G |
Ile10Val |
M0127191 |
MBDAEDNM_00008 |
9325 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
72T>C |
Gly24Gly |
M0127192 |
MBDAEDNM_00009 |
10514 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
357T>G |
Gly119Gly |
M0127193 |
MBDAEDNM_00010 |
11995 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
417C>T |
Asp139Asp |
M0127194 |
MBDAEDNM_00010 |
12694 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1116T>C |
Asn372Asn |
M0127195 |
MBDAEDNM_00010 |
12736 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
1158T>C |
Ala386Ala |
M0127196 |
MBDAEDNM_00007 |
8281 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
180A>G |
Gln60Gln |
M0127197 |
MBDAEDNM_00007 |
8431 |
4 |
Oral |
0.44 |
protein_coding |
synonymous_variant |
LOW |
330T>C |
Val110Val |
M0127198 |
MBDAEDNM_00007 |
8458 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
357G>A |
Ala119Ala |
M0127199 |
MBDAEDNM_00007 |
8686 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
585G>A |
Glu195Glu |
M0127200 |
MBDAEDNM_00007 |
8770 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
669G>A |
Val223Val |
M0127201 |
MBDAEDNM_00007 |
8800 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
699A>G |
Lys233Lys |
M0127202 |
MBDAEDNM_00007 |
8821 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
720A>C |
Leu240Leu |
M0127203 |
MBDAEDNM_00007 |
8869 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
768G>A |
Ser256Ser |
M0127204 |
MBDAEDNM_00005 |
5087 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
258T>C |
Thr86Thr |
M0127205 |
MBDAEDNM_00005 |
5420 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
591C>A |
Ile197Ile |
M0127206 |
MBDAEDNM_00005 |
5423 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
594A>G |
Glu198Glu |
M0127207 |
MBDAEDNM_00005 |
5426 |
3 |
Oral |
0.33 |
protein_coding |
synonymous_variant |
LOW |
597A>G |
Val199Val |
Analysis of virulence factors contributing to bacterial pathogenicity
This table presents virulence factors identified within the plasmid cluster.
Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.
Gene Name |
vf_gene_id |
vf_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
vf_category |
gene_description |
condition |
Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact
This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.
Gene Name |
compound |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
group |
Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents
This table presents antimicrobial resistance genes identified within the plasmid cluster.
Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.
Gene Name |
aro_accession |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
drug_class |
amr_gene_family |
resistance_mechanism |
Analysis of pathogenicity genes to explore pathogen-host interactions
This table presents host pathogen-host interactions within the plasmid cluster.
Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.
Gene Name |
phi_molconn_id |
host gene_name |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
host_descripton |
disease_name |
function |
phenotype_of_mutant |
Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation
This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.
Gene Name |
cazy_id |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification
This table presents transport proteins within the plasmid cluster.
Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.
Gene Name |
tcid |
identity |
evalue |
qstart |
qend |
query_coverage |
subject_coverage |
class_field |
class_term |
subclass |
subclass_term |
family |
family_term |