Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2453
  Reference Plasmid   1111525849768046_bin.37__k141_52964
  Reference Plasmid Size   8277
  Reference Plasmid GC Content   0.37
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0127351 OEGOECEP_00004 4443 5 Oral 0.71 protein_coding synonymous_variant LOW 825A>G Ser275Ser
M0127352 OEGOECEP_00004 4599 5 Oral 0.71 protein_coding synonymous_variant LOW 669G>T Ser223Ser
M0127353 OEGOECEP_00004 4614 5 Oral 0.71 protein_coding synonymous_variant LOW 654T>C Phe218Phe
M0127354 OEGOECEP_00004 4632 5 Oral 0.71 protein_coding synonymous_variant LOW 636C>T Leu212Leu
M0127355 OEGOECEP_00004 4650 5 Oral 0.71 protein_coding synonymous_variant LOW 618G>A Lys206Lys
M0127356 OEGOECEP_00004 4788 4 Oral 0.57 protein_coding synonymous_variant LOW 480C>T Ser160Ser
M0127357 OEGOECEP_00004 4791 4 Oral 0.57 protein_coding synonymous_variant LOW 477C>T Asn159Asn
M0127358 OEGOECEP_00004 4869 4 Oral 0.57 protein_coding synonymous_variant LOW 399A>T Ala133Ala
M0127359 OEGOECEP_00004 4874 3 Oral 0.43 protein_coding synonymous_variant LOW 394T>C Leu132Leu
M0127360 OEGOECEP_00004 4937 4 Oral 0.57 protein_coding missense_variant MODERATE 331G>A Val111Ile
M0127361 OEGOECEP_00004 4938 4 Oral 0.57 protein_coding synonymous_variant LOW 330G>A Thr110Thr
M0127362 OEGOECEP_00004 4945 4 Oral 0.57 protein_coding missense_variant MODERATE 323C>T Ala108Val
M0127363 OEGOECEP_00002 5517 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -3636A>G None
M0127364 OEGOECEP_00002 5530 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -3649G>A None
M0127365 OEGOECEP_00002 5532 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -3651A>G None
M0127366 OEGOECEP_00005 5587 4 Oral 0.57 protein_coding synonymous_variant LOW 423T>C Ile141Ile
M0127367 OEGOECEP_00005 5614 3 Oral 0.43 protein_coding synonymous_variant LOW 396T>A Ala132Ala
M0127368 OEGOECEP_00005 5671 4 Oral 0.57 protein_coding synonymous_variant LOW 339C>T Phe113Phe
M0127369 OEGOECEP_00005 5677 4 Oral 0.57 protein_coding synonymous_variant LOW 333T>C Cys111Cys
M0127370 OEGOECEP_00005 5683 4 Oral 0.57 protein_coding missense_variant MODERATE 327G>T Glu109Asp
M0127371 OEGOECEP_00005 5713 3 Oral 0.43 protein_coding synonymous_variant LOW 297C>T Asn99Asn
M0127372 OEGOECEP_00005 5716 3 Oral 0.43 protein_coding synonymous_variant LOW 294T>C Tyr98Tyr
M0127373 OEGOECEP_00005 5875 4 Oral 0.57 protein_coding synonymous_variant LOW 135G>A Gly45Gly
M0127374 OEGOECEP_00002 6087 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4206A>G None
M0127375 OEGOECEP_00002 6121 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4240G>A None
M0127376 OEGOECEP_00002 6192 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4311T>C None
M0127377 OEGOECEP_00002 6232 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4351T>C None
M0127378 OEGOECEP_00002 6307 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -4426T>C None
M0127379 OEGOECEP_00002 799 4 Oral 0.57 protein_coding synonymous_variant LOW 1083T>C Ser361Ser
M0127380 OEGOECEP_00002 1028 4 Oral 0.57 protein_coding missense_variant MODERATE 854A>G Asn285Ser
M0127381 OEGOECEP_00002 1033 4 Oral 0.57 protein_coding synonymous_variant LOW 849A>T Thr283Thr
M0127382 OEGOECEP_00002 1177 4 Oral 0.57 protein_coding synonymous_variant LOW 705A>G Val235Val
M0127383 OEGOECEP_00002 1201 4 Oral 0.57 protein_coding synonymous_variant LOW 681A>G Glu227Glu
M0127384 OEGOECEP_00002 1213 4 Oral 0.57 protein_coding synonymous_variant LOW 669A>T Pro223Pro
M0127385 OEGOECEP_00002 1306 3 Oral 0.43 protein_coding synonymous_variant LOW 576G>T Val192Val
M0127386 OEGOECEP_00002 1311 3 Oral 0.43 protein_coding missense_variant MODERATE 571C>G Gln191Glu
M0127387 OEGOECEP_00002 1315 3 Oral 0.43 protein_coding synonymous_variant LOW 567G>A Leu189Leu
M0127388 OEGOECEP_00002 1454 4 Oral 0.57 protein_coding missense_variant MODERATE 428C>A Ala143Asp
M0127389 OEGOECEP_00002 1456 4 Oral 0.57 protein_coding synonymous_variant LOW 426A>T Ile142Ile
M0127390 OEGOECEP_00002 1528 4 Oral 0.57 protein_coding synonymous_variant LOW 354A>G Val118Val
M0127391 OEGOECEP_00002 1582 3 Oral 0.43 protein_coding synonymous_variant LOW 300A>G Ala100Ala
M0127392 OEGOECEP_00002 1588 4 Oral 0.57 protein_coding synonymous_variant LOW 294C>T Asn98Asn
M0127393 OEGOECEP_00002 1626 4 Oral 0.57 protein_coding missense_variant MODERATE 256T>C Tyr86His
M0127394 OEGOECEP_00002 1836 4 Oral 0.57 protein_coding missense_variant MODERATE 46C>A Pro16Thr
M0127395 OEGOECEP_00002 1849 4 Oral 0.57 protein_coding synonymous_variant LOW 33A>G Leu11Leu
M0127396 OEGOECEP_00002 1916 4 Oral 0.57 protein_coding upstream_gene_variant MODIFIER -35C>T None
M0127397 OEGOECEP_00003 2250 4 Oral 0.57 protein_coding synonymous_variant LOW 1083T>C Thr361Thr
M0127398 OEGOECEP_00003 2400 4 Oral 0.57 protein_coding synonymous_variant LOW 933A>G Ala311Ala
M0127399 OEGOECEP_00003 2616 4 Oral 0.57 protein_coding synonymous_variant LOW 717G>A Glu239Glu
M0127400 OEGOECEP_00003 2629 3 Oral 0.43 protein_coding missense_variant MODERATE 704C>T Thr235Ile
M0127401 OEGOECEP_00003 2736 3 Oral 0.43 protein_coding synonymous_variant LOW 597T>C Asp199Asp
M0127402 OEGOECEP_00003 2835 3 Oral 0.43 protein_coding synonymous_variant LOW 498A>G Ala166Ala
M0127403 OEGOECEP_00003 2946 4 Oral 0.57 protein_coding synonymous_variant LOW 387A>T Pro129Pro
M0127404 OEGOECEP_00003 2964 4 Oral 0.57 protein_coding synonymous_variant LOW 369T>A Pro123Pro
M0127405 OEGOECEP_00003 2973 4 Oral 0.57 protein_coding missense_variant MODERATE 360G>C Lys120Asn
M0127406 OEGOECEP_00003 3036 3 Oral 0.43 protein_coding synonymous_variant LOW 297C>A Gly99Gly
M0127407 OEGOECEP_00003 3057 3 Oral 0.43 protein_coding synonymous_variant LOW 276T>G Val92Val
M0127408 OEGOECEP_00003 3069 3 Oral 0.43 protein_coding synonymous_variant LOW 264A>T Thr88Thr
M0127409 OEGOECEP_00003 3094 4 Oral 0.57 protein_coding missense_variant MODERATE 239G>A Ser80Asn
M0127410 OEGOECEP_00003 3096 4 Oral 0.57 protein_coding synonymous_variant LOW 237G>A Val79Val
M0127411 OEGOECEP_00003 3111 3 Oral 0.43 protein_coding synonymous_variant LOW 222T>C Asp74Asp
M0127412 OEGOECEP_00003 3159 4 Oral 0.57 protein_coding synonymous_variant LOW 174G>A Arg58Arg
M0127413 OEGOECEP_00003 3180 3 Oral 0.43 protein_coding synonymous_variant LOW 153C>T Asn51Asn
M0127414 OEGOECEP_00004 3396 4 Oral 0.57 protein_coding synonymous_variant LOW 1872A>G Lys624Lys
M0127415 OEGOECEP_00004 3602 4 Oral 0.57 protein_coding missense_variant MODERATE 1666G>T Ala556Ser
M0127416 OEGOECEP_00004 3663 5 Oral 0.71 protein_coding synonymous_variant LOW 1605T>C Tyr535Tyr
M0127417 OEGOECEP_00004 3675 3 Oral 0.43 protein_coding synonymous_variant LOW 1593A>G Val531Val
M0127418 OEGOECEP_00004 3771 5 Oral 0.71 protein_coding synonymous_variant LOW 1497T>C Tyr499Tyr
M0127419 OEGOECEP_00004 3821 3 Oral 0.43 protein_coding synonymous_variant LOW 1447C>T Leu483Leu
M0127420 OEGOECEP_00004 3828 4 Oral 0.57 protein_coding synonymous_variant LOW 1440C>T Gly480Gly
M0127421 OEGOECEP_00004 3849 5 Oral 0.71 protein_coding synonymous_variant LOW 1419T>G Val473Val
M0127422 OEGOECEP_00004 3903 3 Oral 0.43 protein_coding synonymous_variant LOW 1365T>G Val455Val
M0127423 OEGOECEP_00004 3942 3 Oral 0.43 protein_coding synonymous_variant LOW 1326C>G Thr442Thr
M0127424 OEGOECEP_00004 3945 3 Oral 0.43 protein_coding synonymous_variant LOW 1323G>A Lys441Lys
M0127425 OEGOECEP_00004 3969 4 Oral 0.57 protein_coding synonymous_variant LOW 1299T>A Gly433Gly
M0127426 OEGOECEP_00004 4035 4 Oral 0.57 protein_coding synonymous_variant LOW 1233G>A Val411Val
M0127427 OEGOECEP_00004 4134 3 Oral 0.43 protein_coding synonymous_variant LOW 1134C>T Asn378Asn
M0127428 OEGOECEP_00004 4279 4 Oral 0.57 protein_coding missense_variant MODERATE 989A>G Asn330Ser
M0127429 OEGOECEP_00004 4293 4 Oral 0.57 protein_coding synonymous_variant LOW 975A>C Val325Val
M0127430 OEGOECEP_00004 4347 4 Oral 0.57 protein_coding synonymous_variant LOW 921A>T Arg307Arg
M0127431 OEGOECEP_00004 4584 4 Oral 0.57 protein_coding synonymous_variant LOW 684C>T Asn228Asn
M0127432 OEGOECEP_00004 4635 4 Oral 0.57 protein_coding synonymous_variant LOW 633A>G Ser211Ser
M0127433 OEGOECEP_00004 4638 4 Oral 0.57 protein_coding synonymous_variant LOW 630A>G Leu210Leu
M0127434 OEGOECEP_00004 4677 4 Oral 0.57 protein_coding synonymous_variant LOW 591C>T Gly197Gly
M0127435 OEGOECEP_00004 4683 4 Oral 0.57 protein_coding synonymous_variant LOW 585C>T Asp195Asp
M0127436 OEGOECEP_00005 5686 3 Oral 0.43 protein_coding synonymous_variant LOW 324C>T Phe108Phe
M0127437 OEGOECEP_00005 5689 3 Oral 0.43 protein_coding synonymous_variant LOW 321A>G Val107Val
M0127438 OEGOECEP_00005 5815 3 Oral 0.43 protein_coding synonymous_variant LOW 195A>G Glu65Glu
M0127439 OEGOECEP_00005 5839 3 Oral 0.43 protein_coding synonymous_variant LOW 171C>T Asp57Asp
M0127440 OEGOECEP_00005 5950 3 Oral 0.43 protein_coding synonymous_variant LOW 60G>A Ser20Ser
M0127441 OEGOECEP_00005 5953 3 Oral 0.43 protein_coding synonymous_variant LOW 57G>A Leu19Leu
M0127442 OEGOECEP_00002 6722 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -4841G>T None
M0127443 OEGOECEP_00002 6779 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -4898A>G None
M0127444 OEGOECEP_00003 2949 3 Oral 0.43 protein_coding synonymous_variant LOW 384A>T Arg128Arg
M0127445 OEGOECEP_00004 4185 3 Oral 0.43 protein_coding synonymous_variant LOW 1083G>A Leu361Leu
M0127446 OEGOECEP_00004 4187 3 Oral 0.43 protein_coding synonymous_variant LOW 1081T>C Leu361Leu
M0127447 OEGOECEP_00004 4230 3 Oral 0.43 protein_coding synonymous_variant LOW 1038T>C Ala346Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term