Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2455
  Reference Plasmid   1111525849768046_bin.37__k141_54242
  Reference Plasmid Size   1648
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0127449 NJHBLKEB_00001 391 4 Oral 0.80 protein_coding synonymous_variant LOW 348C>T Ile116Ile
M0127450 NJHBLKEB_00001 394 4 Oral 0.80 protein_coding synonymous_variant LOW 351G>A Ala117Ala
M0127451 NJHBLKEB_00001 412 4 Oral 0.80 protein_coding synonymous_variant LOW 369T>C Ala123Ala
M0127452 NJHBLKEB_00001 499 3 Oral 0.60 protein_coding synonymous_variant LOW 456T>C Ile152Ile
M0127453 NJHBLKEB_00001 533 3 Oral 0.60 protein_coding synonymous_variant LOW 490T>C Leu164Leu
M0127454 NJHBLKEB_00001 568 3 Oral 0.60 protein_coding synonymous_variant LOW 525C>T Leu175Leu
M0127455 NJHBLKEB_00001 575 3 Oral 0.60 protein_coding missense_variant MODERATE 532A>T Thr178Ser
M0127456 NJHBLKEB_00001 582 3 Oral 0.60 protein_coding missense_variant MODERATE 539A>T Lys180Met
M0127457 NJHBLKEB_00001 639 3 Oral 0.60 protein_coding missense_variant MODERATE 596T>C Val199Ala
M0127458 NJHBLKEB_00001 749 4 Oral 0.80 protein_coding missense_variant MODERATE 706C>A Leu236Ile
M0127459 NJHBLKEB_00001 850 3 Oral 0.60 protein_coding synonymous_variant LOW 807T>C Gly269Gly
M0127460 NJHBLKEB_00001 872 3 Oral 0.60 protein_coding synonymous_variant LOW 829C>T Leu277Leu
M0127461 NJHBLKEB_00001 880 3 Oral 0.60 protein_coding synonymous_variant LOW 837A>G Glu279Glu
M0127462 NJHBLKEB_00001 883 3 Oral 0.60 protein_coding synonymous_variant LOW 840T>C Ile280Ile
M0127463 NJHBLKEB_00001 939 3 Oral 0.60 protein_coding missense_variant MODERATE 896A>T Tyr299Phe
M0127464 NJHBLKEB_00001 953 3 Oral 0.60 protein_coding missense_variant MODERATE 910A>C Ile304Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term