Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2465
  Reference Plasmid   1111525849768046_bin.37__k141_70230
  Reference Plasmid Size   1885
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0128185 DOBAFGJP_00001 315 7 Oral 1.00 protein_coding synonymous_variant LOW 108A>G Leu36Leu
M0128186 DOBAFGJP_00001 441 6 Oral 0.86 protein_coding synonymous_variant LOW 234T>A Ala78Ala
M0128187 DOBAFGJP_00001 570 5 Oral 0.71 protein_coding synonymous_variant LOW 363C>T Ile121Ile
M0128188 DOBAFGJP_00001 762 7 Oral 1.00 protein_coding synonymous_variant LOW 555T>C Arg185Arg
M0128189 DOBAFGJP_00001 795 3 Oral 0.43 protein_coding synonymous_variant LOW 588G>A Glu196Glu
M0128190 DOBAFGJP_00001 864 4 Oral 0.57 protein_coding synonymous_variant LOW 657G>A Ala219Ala
M0128191 DOBAFGJP_00001 900 7 Oral 1.00 protein_coding synonymous_variant LOW 693A>T Leu231Leu
M0128192 DOBAFGJP_00001 969 6 Oral 0.86 protein_coding synonymous_variant LOW 762A>G Val254Val
M0128193 DOBAFGJP_00001 1068 7 Oral 1.00 protein_coding synonymous_variant LOW 861C>T Thr287Thr
M0128194 DOBAFGJP_00001 1110 4 Oral 0.57 protein_coding synonymous_variant LOW 903T>G Val301Val
M0128195 DOBAFGJP_00001 1799 7 Oral 1.00 protein_coding downstream_gene_variant MODIFIER *341T>C None
M0128196 DOBAFGJP_00001 513 4 Oral 0.57 protein_coding synonymous_variant LOW 306T>C Asn102Asn
M0128197 DOBAFGJP_00001 534 6 Oral 0.86 protein_coding synonymous_variant LOW 327A>G Val109Val
M0128198 DOBAFGJP_00001 1149 5 Oral 0.71 protein_coding synonymous_variant LOW 942A>G Val314Val
M0128199 DOBAFGJP_00001 1152 3 Oral 0.43 protein_coding synonymous_variant LOW 945T>G Val315Val
M0128200 DOBAFGJP_00001 1157 5 Oral 0.71 protein_coding missense_variant MODERATE 950A>G Asn317Ser
M0128201 DOBAFGJP_00001 1158 5 Oral 0.71 protein_coding synonymous_variant LOW 951C>T Asn317Asn
M0128202 DOBAFGJP_00001 1188 5 Oral 0.71 protein_coding synonymous_variant LOW 981A>G Lys327Lys
M0128203 DOBAFGJP_00001 1191 3 Oral 0.43 protein_coding synonymous_variant LOW 984A>T Pro328Pro
M0128204 DOBAFGJP_00001 1257 6 Oral 0.86 protein_coding synonymous_variant LOW 1050T>G Thr350Thr
M0128205 DOBAFGJP_00001 1353 4 Oral 0.57 protein_coding synonymous_variant LOW 1146T>C Asn382Asn
M0128206 DOBAFGJP_00001 1014 3 Oral 0.43 protein_coding synonymous_variant LOW 807G>A Thr269Thr
M0128207 DOBAFGJP_00001 1059 3 Oral 0.43 protein_coding synonymous_variant LOW 852C>T Phe284Phe
M0128208 DOBAFGJP_00001 1796 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *338G>A None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term