Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2467
  Reference Plasmid   1111525849768046_bin.37__k141_74838
  Reference Plasmid Size   2363
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0128248 DCBLJGLK_00001 368 3 Oral 0.60 protein_coding missense_variant MODERATE 323C>A Ala108Glu
M0128249 DCBLJGLK_00001 718 4 Oral 0.80 protein_coding downstream_gene_variant MODIFIER *238G>A None
M0128250 DCBLJGLK_00001 721 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *241A>G None
M0128251 DCBLJGLK_00001 732 3 Oral 0.60 protein_coding downstream_gene_variant MODIFIER *252G>A None
M0128252 DCBLJGLK_00002 733 4 Oral 0.80 protein_coding splice_region_variant&stop_retained_variant LOW 624A>G Ter208Ter
M0128253 DCBLJGLK_00002 763 5 Oral 1.00 protein_coding synonymous_variant LOW 594A>C Ile198Ile
M0128254 DCBLJGLK_00002 766 4 Oral 0.80 protein_coding synonymous_variant LOW 591T>C Leu197Leu
M0128255 DCBLJGLK_00002 874 4 Oral 0.80 protein_coding synonymous_variant LOW 483G>A Gly161Gly
M0128256 DCBLJGLK_00002 943 5 Oral 1.00 protein_coding synonymous_variant LOW 414T>A Pro138Pro
M0128257 DCBLJGLK_00002 979 3 Oral 0.60 protein_coding synonymous_variant LOW 378T>C His126His
M0128258 DCBLJGLK_00002 1009 3 Oral 0.60 protein_coding synonymous_variant LOW 348T>C Ile116Ile
M0128259 DCBLJGLK_00002 1014 3 Oral 0.60 protein_coding missense_variant MODERATE 343G>T Val115Phe
M0128260 DCBLJGLK_00002 1045 3 Oral 0.60 protein_coding synonymous_variant LOW 312C>T Phe104Phe
M0128261 DCBLJGLK_00002 1075 3 Oral 0.60 protein_coding synonymous_variant LOW 282C>T His94His
M0128262 DCBLJGLK_00002 1270 4 Oral 0.80 protein_coding synonymous_variant LOW 87C>T Ile29Ile
M0128263 DCBLJGLK_00002 1317 4 Oral 0.80 protein_coding missense_variant MODERATE 40A>G Thr14Ala
M0128264 DCBLJGLK_00003 1361 4 Oral 0.80 protein_coding synonymous_variant LOW 711C>T Val237Val
M0128265 DCBLJGLK_00003 1379 4 Oral 0.80 protein_coding synonymous_variant LOW 693G>A Leu231Leu
M0128266 DCBLJGLK_00003 1382 4 Oral 0.80 protein_coding synonymous_variant LOW 690A>C Val230Val
M0128267 DCBLJGLK_00003 1442 4 Oral 0.80 protein_coding synonymous_variant LOW 630A>T Gly210Gly
M0128268 DCBLJGLK_00003 1445 4 Oral 0.80 protein_coding synonymous_variant LOW 627C>T Asn209Asn
M0128269 DCBLJGLK_00003 1463 4 Oral 0.80 protein_coding synonymous_variant LOW 609C>T Ile203Ile
M0128270 DCBLJGLK_00003 1520 4 Oral 0.80 protein_coding synonymous_variant LOW 552T>C Asn184Asn
M0128271 DCBLJGLK_00003 1532 4 Oral 0.80 protein_coding synonymous_variant LOW 540G>A Glu180Glu
M0128272 DCBLJGLK_00003 1553 4 Oral 0.80 protein_coding synonymous_variant LOW 519A>G Leu173Leu
M0128273 DCBLJGLK_00003 1555 3 Oral 0.60 protein_coding synonymous_variant LOW 517T>C Leu173Leu
M0128274 DCBLJGLK_00003 1568 3 Oral 0.60 protein_coding synonymous_variant LOW 504C>T Arg168Arg
M0128275 DCBLJGLK_00003 1577 4 Oral 0.80 protein_coding synonymous_variant LOW 495T>C Tyr165Tyr
M0128276 DCBLJGLK_00003 1598 4 Oral 0.80 protein_coding synonymous_variant LOW 474A>C Ile158Ile
M0128277 DCBLJGLK_00003 1613 4 Oral 0.80 protein_coding synonymous_variant LOW 459C>T His153His
M0128278 DCBLJGLK_00003 1657 4 Oral 0.80 protein_coding missense_variant MODERATE 415A>G Ile139Val
M0128279 DCBLJGLK_00003 1673 4 Oral 0.80 protein_coding synonymous_variant LOW 399G>A Gln133Gln
M0128280 DCBLJGLK_00003 1679 4 Oral 0.80 protein_coding synonymous_variant LOW 393C>T Phe131Phe
M0128281 DCBLJGLK_00003 1682 4 Oral 0.80 protein_coding synonymous_variant LOW 390A>T Val130Val
M0128282 DCBLJGLK_00003 1691 3 Oral 0.60 protein_coding synonymous_variant LOW 381G>A Lys127Lys
M0128283 DCBLJGLK_00003 1694 3 Oral 0.60 protein_coding synonymous_variant LOW 378T>C Gly126Gly
M0128284 DCBLJGLK_00003 1715 4 Oral 0.80 protein_coding synonymous_variant LOW 357T>C Asp119Asp
M0128285 DCBLJGLK_00003 1730 4 Oral 0.80 protein_coding synonymous_variant LOW 342A>C Leu114Leu
M0128286 DCBLJGLK_00003 1775 4 Oral 0.80 protein_coding synonymous_variant LOW 297C>T Val99Val
M0128287 DCBLJGLK_00003 1793 4 Oral 0.80 protein_coding synonymous_variant LOW 279G>A Glu93Glu
M0128288 DCBLJGLK_00003 1886 4 Oral 0.80 protein_coding synonymous_variant LOW 186T>C Gly62Gly
M0128289 DCBLJGLK_00003 2018 4 Oral 0.80 protein_coding synonymous_variant LOW 54T>A Gly18Gly
M0128290 DCBLJGLK_00003 2036 4 Oral 0.80 protein_coding synonymous_variant LOW 36T>A Val12Val
M0128291 DCBLJGLK_00004 2089 4 Oral 0.80 protein_coding synonymous_variant LOW 135T>C Ile45Ile
M0128292 DCBLJGLK_00004 2146 4 Oral 0.80 protein_coding synonymous_variant LOW 78T>C Asn26Asn
M0128293 DCBLJGLK_00004 2155 4 Oral 0.80 protein_coding synonymous_variant LOW 69A>G Glu23Glu
M0128294 DCBLJGLK_00004 2179 3 Oral 0.60 protein_coding synonymous_variant LOW 45G>A Arg15Arg
M0128295 DCBLJGLK_00004 2209 4 Oral 0.80 protein_coding synonymous_variant LOW 15G>A Glu5Glu
M0128296 DCBLJGLK_00002 2239 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -883A>G None
M0128297 DCBLJGLK_00002 2242 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -886A>G None
M0128298 DCBLJGLK_00002 2272 5 Oral 1.00 protein_coding upstream_gene_variant MODIFIER -916A>C None
M0128299 DCBLJGLK_00002 2293 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -937C>T None
M0128300 DCBLJGLK_00002 2298 4 Oral 0.80 protein_coding upstream_gene_variant MODIFIER -942T>C None
M0128301 DCBLJGLK_00003 1811 3 Oral 0.60 protein_coding synonymous_variant LOW 261A>T Thr87Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term