Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2470
  Reference Plasmid   1111525849768046_bin.37__k141_76602
  Reference Plasmid Size   6692
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0128511 KNBHNBFJ_00002 44 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -583T>C None
M0128512 KNBHNBFJ_00002 140 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -487A>G None
M0128513 KNBHNBFJ_00002 953 3 Oral 0.75 protein_coding synonymous_variant LOW 327A>G Thr109Thr
M0128514 KNBHNBFJ_00002 1064 3 Oral 0.75 protein_coding synonymous_variant LOW 438A>G Leu146Leu
M0128515 KNBHNBFJ_00002 1076 3 Oral 0.75 protein_coding synonymous_variant LOW 450A>G Leu150Leu
M0128516 KNBHNBFJ_00002 1166 3 Oral 0.75 protein_coding synonymous_variant LOW 540C>T Pro180Pro
M0128517 KNBHNBFJ_00002 1221 3 Oral 0.75 protein_coding synonymous_variant LOW 595C>T Leu199Leu
M0128518 KNBHNBFJ_00002 1223 3 Oral 0.75 protein_coding synonymous_variant LOW 597G>A Leu199Leu
M0128519 KNBHNBFJ_00002 1304 3 Oral 0.75 protein_coding synonymous_variant LOW 678C>A Ala226Ala
M0128520 KNBHNBFJ_00002 1307 3 Oral 0.75 protein_coding synonymous_variant LOW 681T>C Tyr227Tyr
M0128521 KNBHNBFJ_00002 1311 3 Oral 0.75 protein_coding missense_variant MODERATE 685T>G Ser229Ala
M0128522 KNBHNBFJ_00002 1312 3 Oral 0.75 protein_coding stop_gained HIGH 686C>A Ser229*
M0128523 KNBHNBFJ_00002 1435 3 Oral 0.75 protein_coding missense_variant MODERATE 809A>G His270Arg
M0128524 KNBHNBFJ_00002 1505 3 Oral 0.75 protein_coding synonymous_variant LOW 879A>G Leu293Leu
M0128525 KNBHNBFJ_00002 1523 3 Oral 0.75 protein_coding synonymous_variant LOW 897A>C Leu299Leu
M0128526 KNBHNBFJ_00002 1626 3 Oral 0.75 protein_coding synonymous_variant LOW 1000C>A Arg334Arg
M0128527 KNBHNBFJ_00002 1775 3 Oral 0.75 protein_coding synonymous_variant LOW 1149T>C Gly383Gly
M0128528 KNBHNBFJ_00002 1913 3 Oral 0.75 protein_coding synonymous_variant LOW 1287G>T Ala429Ala
M0128529 KNBHNBFJ_00001 2063 3 Oral 0.75 protein_coding upstream_gene_variant MODIFIER -1504T>G None
M0128530 KNBHNBFJ_00003 2099 3 Oral 0.75 protein_coding synonymous_variant LOW 1962T>C Asn654Asn
M0128531 KNBHNBFJ_00003 2153 3 Oral 0.75 protein_coding synonymous_variant LOW 1908C>T Asp636Asp
M0128532 KNBHNBFJ_00003 2501 3 Oral 0.75 protein_coding missense_variant MODERATE 1560T>G Asp520Glu
M0128533 KNBHNBFJ_00003 2968 3 Oral 0.75 protein_coding missense_variant MODERATE 1093A>C Asn365His
M0128534 KNBHNBFJ_00003 3056 3 Oral 0.75 protein_coding synonymous_variant LOW 1005A>T Ile335Ile
M0128535 KNBHNBFJ_00003 3065 3 Oral 0.75 protein_coding synonymous_variant LOW 996G>A Gly332Gly
M0128536 KNBHNBFJ_00003 3074 3 Oral 0.75 protein_coding synonymous_variant LOW 987G>T Leu329Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term