Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2472
  Reference Plasmid   1111525849768046_bin.37__k141_80547
  Reference Plasmid Size   3687
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0128789 LEAJEKHM_00001 3084 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *1221C>T None
M0128790 LEAJEKHM_00001 47 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -41A>C None
M0128791 LEAJEKHM_00001 48 3 Oral 0.43 protein_coding upstream_gene_variant MODIFIER -40T>A None
M0128792 LEAJEKHM_00001 137 3 Oral 0.43 protein_coding missense_variant MODERATE 50G>C Gly17Ala
M0128793 LEAJEKHM_00001 138 4 Oral 0.57 protein_coding synonymous_variant LOW 51G>C Gly17Gly
M0128794 LEAJEKHM_00001 175 4 Oral 0.57 protein_coding missense_variant MODERATE 88T>G Ser30Ala
M0128795 LEAJEKHM_00001 300 3 Oral 0.43 protein_coding synonymous_variant LOW 213T>C Tyr71Tyr
M0128796 LEAJEKHM_00001 411 4 Oral 0.57 protein_coding synonymous_variant LOW 324T>C Tyr108Tyr
M0128797 LEAJEKHM_00001 450 4 Oral 0.57 protein_coding synonymous_variant LOW 363A>G Glu121Glu
M0128798 LEAJEKHM_00001 675 4 Oral 0.57 protein_coding synonymous_variant LOW 588A>G Val196Val
M0128799 LEAJEKHM_00001 1377 3 Oral 0.43 protein_coding synonymous_variant LOW 1290T>C Ser430Ser
M0128800 LEAJEKHM_00001 1582 3 Oral 0.43 protein_coding missense_variant MODERATE 1495A>G Thr499Ala
M0128801 LEAJEKHM_00001 1728 4 Oral 0.57 protein_coding synonymous_variant LOW 1641C>T Asp547Asp
M0128802 LEAJEKHM_00001 1740 3 Oral 0.43 protein_coding synonymous_variant LOW 1653C>T His551His
M0128803 LEAJEKHM_00001 1965 3 Oral 0.43 protein_coding downstream_gene_variant MODIFIER *102T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term