Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2492
  Reference Plasmid   1111525849771023_bin.10__k141_481908
  Reference Plasmid Size   5160
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0041739 HIDNBCNF_00001 444 3 Skin 0.75 protein_coding missense_variant MODERATE 1250G>A Gly417Glu
M0041740 HIDNBCNF_00002 2041 3 Skin 0.75 protein_coding synonymous_variant LOW 1491G>A Gln497Gln
M0041741 HIDNBCNF_00002 2589 3 Skin 0.75 protein_coding synonymous_variant LOW 943T>C Leu315Leu
M0041742 HIDNBCNF_00002 2894 3 Skin 0.75 protein_coding missense_variant MODERATE 638C>T Ala213Val
M0041743 HIDNBCNF_00002 2923 3 Skin 0.75 protein_coding synonymous_variant LOW 609T>G Pro203Pro
M0041744 HIDNBCNF_00002 2950 3 Skin 0.75 protein_coding synonymous_variant LOW 582C>T Phe194Phe
M0041745 HIDNBCNF_00002 2963 3 Skin 0.75 protein_coding missense_variant MODERATE 569A>C Lys190Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
HIDNBCNF_00001 VFG037678 PNAG 70.5 9.2e-187 9 421 0.9741 0.9952 Biofilm poly-beta-1,6 N-acetyl-D-glucosamine synthase experiment
HIDNBCNF_00001 VFG037682 PNAG 70.7 5.3e-186 9 421 0.9741 0.9952 Biofilm poly-beta-1,6 N-acetyl-D-glucosamine synthase prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
HIDNBCNF_00001 APU49449.1|GT2 100 0 1 424 1 1
HIDNBCNF_00002 QXR28564.1|CE4 99.7 0 1 611 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term