Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2499
  Reference Plasmid   1111525849771545_bin.28__k141_130333
  Reference Plasmid Size   135439
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0041898 OJODGFIA_00094 101356 3 Skin 0.19 protein_coding missense_variant MODERATE 95G>C Arg32Thr
M0041899 OJODGFIA_00094 101383 3 Skin 0.19 protein_coding missense_variant MODERATE 122T>C Ile41Thr
M0041900 OJODGFIA_00094 101388 3 Skin 0.19 protein_coding missense_variant MODERATE 127G>C Val43Leu
M0041901 OJODGFIA_00094 101413 3 Skin 0.19 protein_coding missense_variant MODERATE 152C>T Pro51Leu
M0041902 OJODGFIA_00104 110866 4 Skin 0.25 protein_coding missense_variant MODERATE 1369T>G Phe457Val
M0041903 OJODGFIA_00111 118382 3 Skin 0.19 protein_coding synonymous_variant LOW 36T>C Pro12Pro
M0041904 OJODGFIA_00117 121619 3 Skin 0.19 protein_coding missense_variant MODERATE 67G>C Ala23Pro
M0041905 OJODGFIA_00131 132776 4 Skin 0.25 protein_coding synonymous_variant LOW 2601T>C His867His
M0041906 OJODGFIA_00131 132782 4 Skin 0.25 protein_coding synonymous_variant LOW 2595C>T Ile865Ile
M0041907 OJODGFIA_00110 116003 3 Skin 0.19 protein_coding synonymous_variant LOW 621A>G Ala207Ala
M0041908 OJODGFIA_00131 133058 3 Skin 0.19 protein_coding synonymous_variant LOW 2319G>C Ala773Ala
M0041909 OJODGFIA_00131 133403 3 Skin 0.19 protein_coding synonymous_variant LOW 1974T>G Gly658Gly
M0041910 OJODGFIA_00131 133415 3 Skin 0.19 protein_coding synonymous_variant LOW 1962C>G Leu654Leu
M0041911 OJODGFIA_00131 133487 3 Skin 0.19 protein_coding synonymous_variant LOW 1890G>C Ser630Ser
M0041912 OJODGFIA_00131 133493 3 Skin 0.19 protein_coding synonymous_variant LOW 1884G>C Pro628Pro
M0041913 OJODGFIA_00131 133523 3 Skin 0.19 protein_coding synonymous_variant LOW 1854T>C Arg618Arg
M0041914 OJODGFIA_00131 133553 3 Skin 0.19 protein_coding synonymous_variant LOW 1824C>G Thr608Thr
M0041915 OJODGFIA_00131 133591 3 Skin 0.19 protein_coding missense_variant MODERATE 1786G>A Asp596Asn
M0041916 OJODGFIA_00131 133595 3 Skin 0.19 protein_coding synonymous_variant LOW 1782C>G Leu594Leu
M0041917 OJODGFIA_00131 133660 3 Skin 0.19 protein_coding missense_variant MODERATE 1717G>A Gly573Ser
M0041918 OJODGFIA_00131 133667 3 Skin 0.19 protein_coding synonymous_variant LOW 1710G>A Gly570Gly
M0041919 OJODGFIA_00131 133694 3 Skin 0.19 protein_coding synonymous_variant LOW 1683G>A Glu561Glu
M0041920 OJODGFIA_00131 133751 3 Skin 0.19 protein_coding synonymous_variant LOW 1626C>T Val542Val
M0041921 OJODGFIA_00131 133811 3 Skin 0.19 protein_coding synonymous_variant LOW 1566T>C Ile522Ile
M0041922 OJODGFIA_00131 133813 3 Skin 0.19 protein_coding missense_variant MODERATE 1564A>G Ile522Val
M0041923 OJODGFIA_00131 133874 3 Skin 0.19 protein_coding synonymous_variant LOW 1503G>C Arg501Arg
M0041924 OJODGFIA_00131 133883 3 Skin 0.19 protein_coding synonymous_variant LOW 1494G>C Gly498Gly
M0041925 OJODGFIA_00131 133931 3 Skin 0.19 protein_coding synonymous_variant LOW 1446C>T Arg482Arg
M0041926 OJODGFIA_00131 133952 3 Skin 0.19 protein_coding synonymous_variant LOW 1425G>C Arg475Arg
M0041927 OJODGFIA_00131 133955 3 Skin 0.19 protein_coding synonymous_variant LOW 1422T>C Arg474Arg
M0041928 OJODGFIA_00131 133988 3 Skin 0.19 protein_coding synonymous_variant LOW 1389C>G Ala463Ala
M0041929 OJODGFIA_00099 105702 3 Skin 0.19 protein_coding missense_variant MODERATE 962G>A Arg321His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
OJODGFIA_00032 QNE30942.1|GT2 88.9 2.97e-189 7 311 0.9187 0.9871





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term