Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2503
  Reference Plasmid   1111525849771679_bin.1__k141_162442
  Reference Plasmid Size   17053
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0041937 AOCLLDIO_00001 51 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -181G>T None
M0041938 AOCLLDIO_00001 100 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -132T>C None
M0041939 AOCLLDIO_00001 597 3 Skin 0.27 protein_coding synonymous_variant LOW 366C>A Pro122Pro
M0041940 AOCLLDIO_00001 912 5 Skin 0.45 protein_coding synonymous_variant LOW 681A>G Thr227Thr
M0041941 AOCLLDIO_00001 1068 3 Skin 0.27 protein_coding synonymous_variant LOW 837C>T Ala279Ala
M0041942 AOCLLDIO_00003 1363 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1479G>A None
M0041943 AOCLLDIO_00003 1375 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1467A>G None
M0041944 AOCLLDIO_00003 1502 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1340G>A None
M0041945 AOCLLDIO_00003 1536 5 Skin 0.45 protein_coding upstream_gene_variant MODIFIER -1306C>T None
M0041946 AOCLLDIO_00003 1565 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -1277C>A None
M0041947 AOCLLDIO_00003 1666 6 Skin 0.55 protein_coding upstream_gene_variant MODIFIER -1176G>A None
M0041948 AOCLLDIO_00003 1673 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1169A>G None
M0041949 AOCLLDIO_00003 1706 4 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -1136T>G None
M0041950 AOCLLDIO_00003 1722 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -1120G>A None
M0041951 AOCLLDIO_00002 1870 4 Skin 0.36 protein_coding missense_variant MODERATE 847A>C Met283Leu
M0041952 AOCLLDIO_00002 2002 3 Skin 0.27 protein_coding synonymous_variant LOW 715T>C Leu239Leu
M0041953 AOCLLDIO_00002 2020 3 Skin 0.27 protein_coding missense_variant MODERATE 697T>G Ser233Ala
M0041954 AOCLLDIO_00002 2115 4 Skin 0.36 protein_coding missense_variant MODERATE 602C>T Pro201Leu
M0041955 AOCLLDIO_00002 2128 4 Skin 0.36 protein_coding missense_variant MODERATE 589C>A Pro197Thr
M0041956 AOCLLDIO_00002 2345 3 Skin 0.27 protein_coding synonymous_variant LOW 372T>G Pro124Pro
M0041957 AOCLLDIO_00002 2573 3 Skin 0.27 protein_coding synonymous_variant LOW 144T>C Asp48Asp
M0041958 AOCLLDIO_00002 2693 3 Skin 0.27 protein_coding synonymous_variant LOW 24A>C Pro8Pro
M0041959 AOCLLDIO_00002 2793 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -77T>C None
M0041960 AOCLLDIO_00004 4592 4 Skin 0.36 protein_coding synonymous_variant LOW 546C>A Ile182Ile
M0041961 AOCLLDIO_00004 4616 4 Skin 0.36 protein_coding synonymous_variant LOW 570G>C Gly190Gly
M0041962 AOCLLDIO_00004 4706 4 Skin 0.36 protein_coding synonymous_variant LOW 660A>G Ala220Ala
M0041963 AOCLLDIO_00004 5111 4 Skin 0.36 protein_coding synonymous_variant LOW 1065T>C Pro355Pro
M0041964 AOCLLDIO_00005 5337 5 Skin 0.45 protein_coding missense_variant MODERATE 1232A>G Asp411Gly
M0041965 AOCLLDIO_00005 5341 5 Skin 0.45 protein_coding missense_variant MODERATE 1228C>G Pro410Ala
M0041966 AOCLLDIO_00005 5396 3 Skin 0.27 protein_coding synonymous_variant LOW 1173C>G Val391Val
M0041967 AOCLLDIO_00005 5435 3 Skin 0.27 protein_coding synonymous_variant LOW 1134C>T Ile378Ile
M0041968 AOCLLDIO_00005 5459 3 Skin 0.27 protein_coding synonymous_variant LOW 1110C>T Arg370Arg
M0041969 AOCLLDIO_00005 5510 3 Skin 0.27 protein_coding missense_variant MODERATE 1059C>G Asp353Glu
M0041970 AOCLLDIO_00005 5543 3 Skin 0.27 protein_coding synonymous_variant LOW 1026C>G Pro342Pro
M0041971 AOCLLDIO_00005 5567 3 Skin 0.27 protein_coding synonymous_variant LOW 1002G>C Thr334Thr
M0041972 AOCLLDIO_00005 5588 4 Skin 0.36 protein_coding synonymous_variant LOW 981G>C Gly327Gly
M0041973 AOCLLDIO_00005 5624 3 Skin 0.27 protein_coding synonymous_variant LOW 945C>G Arg315Arg
M0041974 AOCLLDIO_00005 5705 4 Skin 0.36 protein_coding synonymous_variant LOW 864T>C Leu288Leu
M0041975 AOCLLDIO_00005 5716 4 Skin 0.36 protein_coding missense_variant MODERATE 853A>G Asn285Asp
M0041976 AOCLLDIO_00005 5825 5 Skin 0.45 protein_coding synonymous_variant LOW 744A>C Ala248Ala
M0041977 AOCLLDIO_00005 6082 3 Skin 0.27 protein_coding synonymous_variant LOW 487C>T Leu163Leu
M0041978 AOCLLDIO_00005 6083 3 Skin 0.27 protein_coding synonymous_variant LOW 486G>C Ala162Ala
M0041979 AOCLLDIO_00005 6158 4 Skin 0.36 protein_coding synonymous_variant LOW 411T>C Arg137Arg
M0041980 AOCLLDIO_00005 6218 4 Skin 0.36 protein_coding synonymous_variant LOW 351A>G Gln117Gln
M0041981 AOCLLDIO_00005 6242 3 Skin 0.27 protein_coding synonymous_variant LOW 327C>T Pro109Pro
M0041982 AOCLLDIO_00006 6650 3 Skin 0.27 protein_coding synonymous_variant LOW 1785T>G Ala595Ala
M0041983 AOCLLDIO_00006 6687 3 Skin 0.27 protein_coding missense_variant MODERATE 1748T>G Val583Gly
M0041984 AOCLLDIO_00006 6755 3 Skin 0.27 protein_coding synonymous_variant LOW 1680A>G Gly560Gly
M0041985 AOCLLDIO_00001 91 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -141A>G None
M0041986 AOCLLDIO_00003 1483 3 Skin 0.27 protein_coding upstream_gene_variant MODIFIER -1359T>G None
M0041987 AOCLLDIO_00006 8018 3 Skin 0.27 protein_coding synonymous_variant LOW 417T>C Arg139Arg
M0041988 AOCLLDIO_00006 8066 3 Skin 0.27 protein_coding synonymous_variant LOW 369C>G Ser123Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
AOCLLDIO_00006 QJD16280.1|GT14 73.3 5.56e-291 21 575 0.9204 0.9113
AOCLLDIO_00007 QJD16281.1|GT0 81.6 3.17e-196 1 310 1 0.981
AOCLLDIO_00008 ARJ70848.1|GT0 74.7 8.51e-184 36 364 0.8844 0.991





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term