Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2508
  Reference Plasmid   1111525849771679_bin.22__k141_539708
  Reference Plasmid Size   7880
  Reference Plasmid GC Content   0.29
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0042645 BNDLGEFL_00001 792 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -357A>T None
M0042646 BNDLGEFL_00002 1015 3 Skin 0.33 protein_coding missense_variant MODERATE 154A>G Asn52Asp
M0042647 BNDLGEFL_00001 1294 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -859C>A None
M0042648 BNDLGEFL_00001 1330 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -895C>A None
M0042649 BNDLGEFL_00001 1333 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -898G>T None
M0042650 BNDLGEFL_00001 1360 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -925C>G None
M0042651 BNDLGEFL_00001 1368 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -933T>A None
M0042652 BNDLGEFL_00001 1385 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -950T>G None
M0042653 BNDLGEFL_00001 1448 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -1013C>T None
M0042654 BNDLGEFL_00001 1449 4 Skin 0.44 protein_coding upstream_gene_variant MODIFIER -1014A>T None
M0042655 BNDLGEFL_00003 1507 3 Skin 0.33 protein_coding missense_variant MODERATE 35A>C Lys12Thr
M0042656 BNDLGEFL_00003 1508 3 Skin 0.33 protein_coding missense_variant MODERATE 36A>C Lys12Asn
M0042657 BNDLGEFL_00003 1520 3 Skin 0.33 protein_coding synonymous_variant LOW 48A>G Ser16Ser
M0042658 BNDLGEFL_00003 1525 3 Skin 0.33 protein_coding missense_variant MODERATE 53C>T Thr18Ile
M0042659 BNDLGEFL_00003 1529 3 Skin 0.33 protein_coding synonymous_variant LOW 57C>T Phe19Phe
M0042660 BNDLGEFL_00003 1690 3 Skin 0.33 protein_coding missense_variant MODERATE 218C>T Ala73Val
M0042661 BNDLGEFL_00004 1918 3 Skin 0.33 protein_coding synonymous_variant LOW 132A>C Arg44Arg
M0042662 BNDLGEFL_00001 2285 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -1850T>C None
M0042663 BNDLGEFL_00005 2617 5 Skin 0.56 protein_coding synonymous_variant LOW 216A>C Ile72Ile
M0042664 BNDLGEFL_00006 3144 5 Skin 0.56 protein_coding missense_variant MODERATE 274G>T Asp92Tyr
M0042665 BNDLGEFL_00006 3218 4 Skin 0.44 protein_coding synonymous_variant LOW 348C>T Asp116Asp
M0042666 BNDLGEFL_00006 3326 6 Skin 0.67 protein_coding missense_variant MODERATE 456C>A His152Gln
M0042667 BNDLGEFL_00006 3457 4 Skin 0.44 protein_coding missense_variant MODERATE 587C>T Thr196Ile
M0042668 BNDLGEFL_00006 3907 5 Skin 0.56 protein_coding missense_variant MODERATE 1037A>G Asn346Ser
M0042669 BNDLGEFL_00006 4094 3 Skin 0.33 protein_coding synonymous_variant LOW 1224A>G Glu408Glu
M0042670 BNDLGEFL_00006 4097 3 Skin 0.33 protein_coding synonymous_variant LOW 1227G>A Thr409Thr
M0042671 BNDLGEFL_00006 4106 3 Skin 0.33 protein_coding missense_variant MODERATE 1236A>C Arg412Ser
M0042672 BNDLGEFL_00006 4109 3 Skin 0.33 protein_coding synonymous_variant LOW 1239A>C Ser413Ser
M0042673 BNDLGEFL_00006 4115 3 Skin 0.33 protein_coding synonymous_variant LOW 1245T>C Arg415Arg
M0042674 BNDLGEFL_00006 4119 4 Skin 0.44 protein_coding synonymous_variant LOW 1249T>C Leu417Leu
M0042675 BNDLGEFL_00006 4147 4 Skin 0.44 protein_coding missense_variant MODERATE 1277A>G Asn426Ser
M0042676 BNDLGEFL_00006 4171 5 Skin 0.56 protein_coding missense_variant MODERATE 1301A>C Gln434Pro
M0042677 BNDLGEFL_00006 4198 4 Skin 0.44 protein_coding missense_variant MODERATE 1328G>C Ser443Thr
M0042678 BNDLGEFL_00006 4202 4 Skin 0.44 protein_coding synonymous_variant LOW 1332G>A Leu444Leu
M0042679 BNDLGEFL_00006 4205 4 Skin 0.44 protein_coding synonymous_variant LOW 1335T>A Ala445Ala
M0042680 BNDLGEFL_00006 4214 4 Skin 0.44 protein_coding synonymous_variant LOW 1344A>G Gly448Gly
M0042681 BNDLGEFL_00006 4218 4 Skin 0.44 protein_coding missense_variant MODERATE 1348A>G Ile450Val
M0042682 BNDLGEFL_00006 4245 4 Skin 0.44 protein_coding missense_variant MODERATE 1375A>C Asn459His
M0042683 BNDLGEFL_00007 4541 3 Skin 0.33 protein_coding missense_variant MODERATE 145G>A Val49Ile
M0042684 BNDLGEFL_00007 4606 3 Skin 0.33 protein_coding synonymous_variant LOW 210A>T Ala70Ala
M0042685 BNDLGEFL_00001 4779 3 Skin 0.33 protein_coding upstream_gene_variant MODIFIER -4344T>C None
M0042686 BNDLGEFL_00006 4004 3 Skin 0.33 protein_coding synonymous_variant LOW 1134A>G Pro378Pro
M0042687 BNDLGEFL_00006 4018 3 Skin 0.33 protein_coding missense_variant MODERATE 1148T>C Val383Ala
M0042688 BNDLGEFL_00006 4029 3 Skin 0.33 protein_coding missense_variant MODERATE 1159T>A Tyr387Asn
M0042689 BNDLGEFL_00006 4032 3 Skin 0.33 protein_coding synonymous_variant LOW 1162T>C Leu388Leu
M0042690 BNDLGEFL_00006 4038 3 Skin 0.33 protein_coding missense_variant MODERATE 1168A>G Asn390Asp
M0042691 BNDLGEFL_00006 4062 3 Skin 0.33 protein_coding missense_variant MODERATE 1192A>G Ile398Val
M0042692 BNDLGEFL_00006 4064 3 Skin 0.33 protein_coding synonymous_variant LOW 1194T>A Ile398Ile
M0042693 BNDLGEFL_00006 4065 3 Skin 0.33 protein_coding synonymous_variant LOW 1195T>C Leu399Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term