Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2514
  Reference Plasmid   1111525849771950_bin.29__k141_282805
  Reference Plasmid Size   10641
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0042713 BCNKIICN_00007 9467 3 Skin 0.43 protein_coding missense_variant MODERATE 1304G>A Arg435Gln
M0042714 BCNKIICN_00001 207 3 Skin 0.43 protein_coding missense_variant MODERATE 1G>A Val1Met
M0042715 BCNKIICN_00001 249 3 Skin 0.43 protein_coding missense_variant MODERATE 43A>G Thr15Ala
M0042716 BCNKIICN_00001 321 3 Skin 0.43 protein_coding missense_variant MODERATE 115G>A Ala39Thr
M0042717 BCNKIICN_00001 561 3 Skin 0.43 protein_coding missense_variant MODERATE 355T>G Cys119Gly
M0042718 BCNKIICN_00001 910 3 Skin 0.43 protein_coding missense_variant MODERATE 704T>C Ile235Thr
M0042719 BCNKIICN_00001 917 3 Skin 0.43 protein_coding synonymous_variant LOW 711T>C Arg237Arg
M0042720 BCNKIICN_00002 1029 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -154T>C None
M0042721 BCNKIICN_00004 1795 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -2584T>A None
M0042722 BCNKIICN_00003 1984 3 Skin 0.43 protein_coding missense_variant MODERATE 2237A>C Asp746Ala
M0042723 BCNKIICN_00003 2044 3 Skin 0.43 protein_coding missense_variant MODERATE 2177C>T Thr726Met
M0042724 BCNKIICN_00003 2098 3 Skin 0.43 protein_coding missense_variant MODERATE 2123C>A Pro708Gln
M0042725 BCNKIICN_00003 2406 3 Skin 0.43 protein_coding synonymous_variant LOW 1815G>A Leu605Leu
M0042726 BCNKIICN_00003 2445 3 Skin 0.43 protein_coding synonymous_variant LOW 1776G>A Ala592Ala
M0042727 BCNKIICN_00003 3219 3 Skin 0.43 protein_coding synonymous_variant LOW 1002G>A Gln334Gln
M0042728 BCNKIICN_00003 3733 3 Skin 0.43 protein_coding missense_variant MODERATE 488G>A Gly163Asp
M0042729 BCNKIICN_00003 3957 3 Skin 0.43 protein_coding synonymous_variant LOW 264C>T Ile88Ile
M0042730 BCNKIICN_00003 3960 3 Skin 0.43 protein_coding synonymous_variant LOW 261C>T His87His
M0042731 BCNKIICN_00003 3966 3 Skin 0.43 protein_coding synonymous_variant LOW 255T>A Arg85Arg
M0042732 BCNKIICN_00003 3969 3 Skin 0.43 protein_coding synonymous_variant LOW 252G>A Lys84Lys
M0042733 BCNKIICN_00003 3975 3 Skin 0.43 protein_coding synonymous_variant LOW 246C>G Gly82Gly
M0042734 BCNKIICN_00003 3984 3 Skin 0.43 protein_coding synonymous_variant LOW 237C>G Val79Val
M0042735 BCNKIICN_00003 3993 3 Skin 0.43 protein_coding missense_variant MODERATE 228G>C Met76Ile
M0042736 BCNKIICN_00003 3994 3 Skin 0.43 protein_coding missense_variant MODERATE 227T>C Met76Thr
M0042737 BCNKIICN_00003 3996 3 Skin 0.43 protein_coding synonymous_variant LOW 225T>C Gly75Gly
M0042738 BCNKIICN_00003 4002 3 Skin 0.43 protein_coding synonymous_variant LOW 219G>C Gly73Gly
M0042739 BCNKIICN_00003 4005 3 Skin 0.43 protein_coding synonymous_variant LOW 216C>T Pro72Pro
M0042740 BCNKIICN_00003 4014 3 Skin 0.43 protein_coding synonymous_variant LOW 207A>G Gly69Gly
M0042741 BCNKIICN_00003 4110 3 Skin 0.43 protein_coding synonymous_variant LOW 111G>C Ala37Ala
M0042742 BCNKIICN_00003 4143 3 Skin 0.43 protein_coding synonymous_variant LOW 78G>A Pro26Pro
M0042743 BCNKIICN_00003 4146 3 Skin 0.43 protein_coding synonymous_variant LOW 75C>T Ile25Ile
M0042744 BCNKIICN_00003 4167 3 Skin 0.43 protein_coding synonymous_variant LOW 54C>G Leu18Leu
M0042745 BCNKIICN_00003 4170 3 Skin 0.43 protein_coding synonymous_variant LOW 51T>C Val17Val
M0042746 BCNKIICN_00003 4212 3 Skin 0.43 protein_coding synonymous_variant LOW 9T>C His3His
M0042747 BCNKIICN_00003 4214 3 Skin 0.43 protein_coding missense_variant MODERATE 7C>A His3Asn
M0042748 BCNKIICN_00003 4215 3 Skin 0.43 protein_coding synonymous_variant LOW 6C>A Ser2Ser
M0042749 BCNKIICN_00003 4268 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -48C>G None
M0042750 BCNKIICN_00003 4278 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -58C>T None
M0042751 BCNKIICN_00003 4279 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -59G>C None
M0042752 BCNKIICN_00003 4280 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -60C>G None
M0042753 BCNKIICN_00003 4281 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -61G>A None
M0042754 BCNKIICN_00003 4283 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -63C>T None
M0042755 BCNKIICN_00003 4304 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -84C>G None
M0042756 BCNKIICN_00003 4305 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -85C>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term