Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2520
  Reference Plasmid   1111525849772285_bin.15__k141_9345
  Reference Plasmid Size   11867
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0141294 DJEBNCFC_00002 1879 3 Vaginal 0.38 protein_coding downstream_gene_variant MODIFIER *13C>A None
M0141295 DJEBNCFC_00002 1955 3 Vaginal 0.38 protein_coding synonymous_variant LOW 234C>T Cys78Cys
M0141296 DJEBNCFC_00002 2549 3 Vaginal 0.38 protein_coding upstream_gene_variant MODIFIER -361T>G None
M0141297 DJEBNCFC_00003 3889 3 Vaginal 0.38 protein_coding missense_variant MODERATE 277C>A Gln93Lys
M0141298 DJEBNCFC_00007 7632 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1663A>G Ile555Val
M0141299 DJEBNCFC_00007 7735 3 Vaginal 0.38 protein_coding synonymous_variant LOW 1560G>A Leu520Leu
M0141300 DJEBNCFC_00007 7905 3 Vaginal 0.38 protein_coding missense_variant MODERATE 1390A>C Lys464Gln
M0141301 DJEBNCFC_00007 8656 4 Vaginal 0.50 protein_coding synonymous_variant LOW 639A>G Glu213Glu
M0141302 DJEBNCFC_00004 9565 4 Vaginal 0.50 protein_coding upstream_gene_variant MODIFIER -4598T>C None
M0141303 DJEBNCFC_00004 9567 3 Vaginal 0.38 protein_coding upstream_gene_variant MODIFIER -4600A>G None
M0141304 DJEBNCFC_00004 9570 4 Vaginal 0.50 protein_coding upstream_gene_variant MODIFIER -4603G>A None
M0141305 DJEBNCFC_00005 10227 7 Vaginal 0.88 protein_coding upstream_gene_variant MODIFIER -4484A>G None
M0141306 DJEBNCFC_00005 10270 7 Vaginal 0.88 protein_coding upstream_gene_variant MODIFIER -4527C>A None
M0141307 DJEBNCFC_00005 10334 8 Vaginal 1.00 protein_coding upstream_gene_variant MODIFIER -4591T>G None
M0141308 DJEBNCFC_00005 10231 3 Vaginal 0.38 protein_coding upstream_gene_variant MODIFIER -4488T>C None
M0141309 DJEBNCFC_00009 11163 3 Vaginal 0.38 protein_coding synonymous_variant LOW 342G>A Ser114Ser
M0141310 DJEBNCFC_00009 11220 3 Vaginal 0.38 protein_coding synonymous_variant LOW 285C>T Cys95Cys
M0141311 DJEBNCFC_00009 11226 3 Vaginal 0.38 protein_coding missense_variant MODERATE 279T>A Ser93Arg
M0141312 DJEBNCFC_00009 11291 3 Vaginal 0.38 protein_coding missense_variant MODERATE 214A>G Ile72Val
M0141313 DJEBNCFC_00009 11328 3 Vaginal 0.38 protein_coding synonymous_variant LOW 177T>C Ala59Ala
M0141314 DJEBNCFC_00009 11358 3 Vaginal 0.38 protein_coding synonymous_variant LOW 147G>A Arg49Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term