Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2529
  Reference Plasmid   1111525849772973_bin.11__k141_389758
  Reference Plasmid Size   6713
  Reference Plasmid GC Content   0.66
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0045726 HOIKJOKA_00001 356 7 Skin 0.28 protein_coding synonymous_variant LOW 195A>G Gln65Gln
M0045727 HOIKJOKA_00001 358 7 Skin 0.28 protein_coding missense_variant MODERATE 193C>A Gln65Lys
M0045728 HOIKJOKA_00001 501 7 Skin 0.28 protein_coding missense_variant MODERATE 50C>T Ala17Val
M0045729 HOIKJOKA_00001 551 7 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -1C>T None
M0045730 HOIKJOKA_00002 932 7 Skin 0.28 protein_coding synonymous_variant LOW 183C>T Ser61Ser
M0045731 HOIKJOKA_00001 1695 7 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -1145G>T None
M0045732 HOIKJOKA_00003 2607 4 Skin 0.16 protein_coding synonymous_variant LOW 822G>C Ser274Ser
M0045733 HOIKJOKA_00001 2753 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -2203A>T None
M0045734 HOIKJOKA_00001 2786 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2236T>C None
M0045735 HOIKJOKA_00005 4029 5 Skin 0.20 protein_coding missense_variant MODERATE 148A>G Ile50Val
M0045736 HOIKJOKA_00005 4036 5 Skin 0.20 protein_coding synonymous_variant LOW 141A>G Ala47Ala
M0045737 HOIKJOKA_00005 4075 5 Skin 0.20 protein_coding synonymous_variant LOW 102T>C Phe34Phe
M0045738 HOIKJOKA_00001 4242 13 Skin 0.52 protein_coding upstream_gene_variant MODIFIER -3692T>C None
M0045739 HOIKJOKA_00006 4539 8 Skin 0.32 protein_coding synonymous_variant LOW 162A>G Lys54Lys
M0045740 HOIKJOKA_00006 4679 6 Skin 0.24 protein_coding missense_variant MODERATE 302T>C Ile101Thr
M0045741 HOIKJOKA_00006 4689 6 Skin 0.24 protein_coding synonymous_variant LOW 312T>C Ser104Ser
M0045742 HOIKJOKA_00007 5098 12 Skin 0.48 protein_coding synonymous_variant LOW 132C>T Ser44Ser
M0045743 HOIKJOKA_00001 5266 12 Skin 0.48 protein_coding upstream_gene_variant MODIFIER -4716T>C None
M0045744 HOIKJOKA_00001 5292 10 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -4742C>T None
M0045745 HOIKJOKA_00005 6418 10 Skin 0.40 protein_coding upstream_gene_variant MODIFIER -2242C>T None
M0045746 HOIKJOKA_00005 6649 12 Skin 0.48 protein_coding upstream_gene_variant MODIFIER -2473G>C None
M0045747 HOIKJOKA_00001 5534 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -4984C>G None
M0045748 HOIKJOKA_00001 5540 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -4990T>C None
M0045749 HOIKJOKA_00005 5590 7 Skin 0.28 protein_coding upstream_gene_variant MODIFIER -1414G>A None
M0045750 HOIKJOKA_00005 6592 12 Skin 0.48 protein_coding upstream_gene_variant MODIFIER -2416T>C None
M0045751 HOIKJOKA_00002 202 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -548C>T None
M0045752 HOIKJOKA_00002 216 6 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -534A>G None
M0045753 HOIKJOKA_00001 227 6 Skin 0.24 protein_coding synonymous_variant LOW 324T>C Ala108Ala
M0045754 HOIKJOKA_00001 236 6 Skin 0.24 protein_coding synonymous_variant LOW 315G>A Glu105Glu
M0045755 HOIKJOKA_00001 254 6 Skin 0.24 protein_coding synonymous_variant LOW 297A>G Lys99Lys
M0045756 HOIKJOKA_00001 287 6 Skin 0.24 protein_coding synonymous_variant LOW 264T>C Asp88Asp
M0045757 HOIKJOKA_00002 974 7 Skin 0.28 protein_coding synonymous_variant LOW 225C>G Leu75Leu
M0045758 HOIKJOKA_00002 980 7 Skin 0.28 protein_coding synonymous_variant LOW 231C>G Ala77Ala
M0045759 HOIKJOKA_00006 4819 9 Skin 0.36 protein_coding missense_variant MODERATE 442C>T Arg148Cys
M0045760 HOIKJOKA_00006 4842 10 Skin 0.40 protein_coding synonymous_variant LOW 465G>A Arg155Arg
M0045761 HOIKJOKA_00006 4845 10 Skin 0.40 protein_coding synonymous_variant LOW 468C>T Pro156Pro
M0045762 HOIKJOKA_00002 100 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -650G>A None
M0045763 HOIKJOKA_00002 103 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -647A>G None
M0045764 HOIKJOKA_00002 142 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -608T>C None
M0045765 HOIKJOKA_00005 3928 6 Skin 0.24 protein_coding synonymous_variant LOW 249A>G Ser83Ser
M0045766 HOIKJOKA_00005 3940 5 Skin 0.20 protein_coding synonymous_variant LOW 237T>C Phe79Phe
M0045767 HOIKJOKA_00005 3970 6 Skin 0.24 protein_coding synonymous_variant LOW 207G>C Arg69Arg
M0045768 HOIKJOKA_00006 4884 10 Skin 0.40 protein_coding synonymous_variant LOW 507G>C Ala169Ala
M0045769 HOIKJOKA_00005 5647 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1471G>A None
M0045770 HOIKJOKA_00005 5668 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1492A>C None
M0045771 HOIKJOKA_00005 5671 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1495T>C None
M0045772 HOIKJOKA_00005 5680 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1504G>C None
M0045773 HOIKJOKA_00005 5689 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1513G>A None
M0045774 HOIKJOKA_00005 5701 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1525T>C None
M0045775 HOIKJOKA_00005 5707 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1531C>G None
M0045776 HOIKJOKA_00005 5710 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1534A>G None
M0045777 HOIKJOKA_00005 5719 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1543C>T None
M0045778 HOIKJOKA_00005 5720 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -1544T>G None
M0045779 HOIKJOKA_00005 5753 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -1577C>A None
M0045780 HOIKJOKA_00005 6319 5 Skin 0.20 protein_coding upstream_gene_variant MODIFIER -2143A>G None
M0045781 HOIKJOKA_00006 4920 7 Skin 0.28 protein_coding synonymous_variant LOW 543T>C Asp181Asp
M0045782 HOIKJOKA_00001 5250 4 Skin 0.16 protein_coding upstream_gene_variant MODIFIER -4700C>T None
M0045783 HOIKJOKA_00006 4602 4 Skin 0.16 protein_coding synonymous_variant LOW 225G>T Arg75Arg
M0045784 HOIKJOKA_00006 4638 4 Skin 0.16 protein_coding synonymous_variant LOW 261C>T Ala87Ala
M0045785 HOIKJOKA_00001 5364 3 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -4814T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term