Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2539
  Reference Plasmid   1111525849852226_bin.9__k141_483923
  Reference Plasmid Size   11888
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0046893 BNAENMOK_00005 6537 5 Skin 0.08 protein_coding synonymous_variant LOW 615T>C Ala205Ala
M0046894 BNAENMOK_00003 7972 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4176T>C None
M0046895 BNAENMOK_00008 9001 48 Skin 0.81 protein_coding synonymous_variant LOW 285T>C Ala95Ala
M0046896 BNAENMOK_00010 10199 36 Skin 0.61 protein_coding synonymous_variant LOW 303A>G Gln101Gln
M0046897 BNAENMOK_00004 5287 34 Skin 0.58 protein_coding synonymous_variant LOW 612C>T Arg204Arg
M0046898 BNAENMOK_00003 7731 7 Skin 0.12 protein_coding upstream_gene_variant MODIFIER -3935G>T None
M0046899 BNAENMOK_00003 8031 11 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4235C>G None
M0046900 BNAENMOK_00003 8392 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4596C>A None
M0046901 BNAENMOK_00003 8412 6 Skin 0.10 protein_coding upstream_gene_variant MODIFIER -4616G>T None
M0046902 BNAENMOK_00009 9762 3 Skin 0.05 protein_coding missense_variant MODERATE 475A>G Thr159Ala
M0046903 BNAENMOK_00003 2912 4 Skin 0.07 protein_coding synonymous_variant LOW 885T>C Thr295Thr
M0046904 BNAENMOK_00003 3129 4 Skin 0.07 protein_coding missense_variant MODERATE 668G>A Arg223His
M0046905 BNAENMOK_00003 3239 4 Skin 0.07 protein_coding synonymous_variant LOW 558T>C Ala186Ala
M0046906 BNAENMOK_00005 6957 6 Skin 0.10 protein_coding synonymous_variant LOW 195A>G Gly65Gly
M0046907 BNAENMOK_00003 7366 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3570T>C None
M0046908 BNAENMOK_00003 7390 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -3594G>A None
M0046909 BNAENMOK_00005 6810 3 Skin 0.05 protein_coding synonymous_variant LOW 342T>C Ser114Ser
M0046910 BNAENMOK_00004 5563 6 Skin 0.10 protein_coding synonymous_variant LOW 336T>C Val112Val
M0046911 BNAENMOK_00009 9338 4 Skin 0.07 protein_coding synonymous_variant LOW 51A>T Pro17Pro
M0046912 BNAENMOK_00004 4036 6 Skin 0.10 protein_coding synonymous_variant LOW 1863T>C Gly621Gly
M0046913 BNAENMOK_00004 4079 4 Skin 0.07 protein_coding missense_variant MODERATE 1820C>T Ala607Val
M0046914 BNAENMOK_00004 4087 4 Skin 0.07 protein_coding missense_variant MODERATE 1812C>A Asp604Glu
M0046915 BNAENMOK_00005 6206 6 Skin 0.10 protein_coding missense_variant MODERATE 946G>A Ala316Thr
M0046916 BNAENMOK_00005 6218 6 Skin 0.10 protein_coding synonymous_variant LOW 934C>A Arg312Arg
M0046917 BNAENMOK_00001 1127 15 Skin 0.25 protein_coding synonymous_variant LOW 939G>A Glu313Glu
M0046918 BNAENMOK_00003 3306 5 Skin 0.08 protein_coding missense_variant MODERATE 491T>G Ile164Ser
M0046919 BNAENMOK_00003 3609 4 Skin 0.07 protein_coding missense_variant MODERATE 188A>G Asn63Ser
M0046920 BNAENMOK_00005 11071 4 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3920A>G None
M0046921 BNAENMOK_00005 6315 4 Skin 0.07 protein_coding synonymous_variant LOW 837G>A Ala279Ala
M0046922 BNAENMOK_00005 7020 3 Skin 0.05 protein_coding synonymous_variant LOW 132C>T Phe44Phe
M0046923 BNAENMOK_00003 7863 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4067G>A None
M0046924 BNAENMOK_00003 3540 4 Skin 0.07 protein_coding missense_variant MODERATE 257G>T Arg86Leu
M0046925 BNAENMOK_00004 5728 4 Skin 0.07 protein_coding synonymous_variant LOW 171G>T Gly57Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term