Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2545
  Reference Plasmid   1111525849852267_bin.8__k141_791484
  Reference Plasmid Size   5978
  Reference Plasmid GC Content   0.43
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0129655 CPHCLNFC_00003 3225 3 Oral 0.75 protein_coding missense_variant MODERATE 2425A>G Asn809Asp
M0129656 CPHCLNFC_00003 3475 3 Oral 0.75 protein_coding synonymous_variant LOW 2175G>T Pro725Pro
M0129657 CPHCLNFC_00001 794 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *128T>C None
M0129658 CPHCLNFC_00001 796 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *126A>G None
M0129659 CPHCLNFC_00001 915 3 Oral 0.75 protein_coding downstream_gene_variant MODIFIER *7C>A None
M0129660 CPHCLNFC_00001 1222 3 Oral 0.75 protein_coding synonymous_variant LOW 1197G>A Lys399Lys
M0129661 CPHCLNFC_00001 1231 3 Oral 0.75 protein_coding synonymous_variant LOW 1188C>A Thr396Thr
M0129662 CPHCLNFC_00001 1520 3 Oral 0.75 protein_coding missense_variant MODERATE 899T>C Val300Ala
M0129663 CPHCLNFC_00001 1647 3 Oral 0.75 protein_coding missense_variant MODERATE 772A>G Ile258Val
M0129664 CPHCLNFC_00001 1785 3 Oral 0.75 protein_coding missense_variant MODERATE 634A>C Thr212Pro
M0129665 CPHCLNFC_00001 2007 3 Oral 0.75 protein_coding missense_variant MODERATE 412A>G Thr138Ala
M0129666 CPHCLNFC_00001 2161 3 Oral 0.75 protein_coding synonymous_variant LOW 258C>T Thr86Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term