Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2552
  Reference Plasmid   1111525849852366_bin.5__k141_697859
  Reference Plasmid Size   7136
  Reference Plasmid GC Content   0.39
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0046962 ACLNNIFM_00001 555 3 Skin 0.75 protein_coding synonymous_variant LOW 510A>G Arg170Arg
M0046963 ACLNNIFM_00001 609 3 Skin 0.75 protein_coding synonymous_variant LOW 564T>C Asp188Asp
M0046964 ACLNNIFM_00002 660 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -145A>G None
M0046965 ACLNNIFM_00002 751 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -54C>T None
M0046966 ACLNNIFM_00002 799 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -6G>T None
M0046967 ACLNNIFM_00002 843 3 Skin 0.75 protein_coding synonymous_variant LOW 39T>C Ser13Ser
M0046968 ACLNNIFM_00002 985 3 Skin 0.75 protein_coding synonymous_variant LOW 181T>C Leu61Leu
M0046969 ACLNNIFM_00002 987 3 Skin 0.75 protein_coding synonymous_variant LOW 183G>A Leu61Leu
M0046970 ACLNNIFM_00002 988 3 Skin 0.75 protein_coding synonymous_variant LOW 184T>C Leu62Leu
M0046971 ACLNNIFM_00002 1028 3 Skin 0.75 protein_coding missense_variant MODERATE 224A>T Asp75Val
M0046972 ACLNNIFM_00002 1251 3 Skin 0.75 protein_coding missense_variant MODERATE 447T>G Ile149Met
M0046973 ACLNNIFM_00002 1252 3 Skin 0.75 protein_coding missense_variant MODERATE 448A>G Thr150Ala
M0046974 ACLNNIFM_00002 1395 3 Skin 0.75 protein_coding synonymous_variant LOW 591G>A Val197Val
M0046975 ACLNNIFM_00002 1404 3 Skin 0.75 protein_coding missense_variant MODERATE 600A>T Lys200Asn
M0046976 ACLNNIFM_00002 1434 3 Skin 0.75 protein_coding synonymous_variant LOW 630C>T Ile210Ile
M0046977 ACLNNIFM_00003 1792 3 Skin 0.75 protein_coding synonymous_variant LOW 261C>A Gly87Gly
M0046978 ACLNNIFM_00003 1879 3 Skin 0.75 protein_coding synonymous_variant LOW 348G>A Gln116Gln
M0046979 ACLNNIFM_00003 2064 3 Skin 0.75 protein_coding missense_variant MODERATE 533A>C Asn178Thr
M0046980 ACLNNIFM_00003 2092 3 Skin 0.75 protein_coding synonymous_variant LOW 561A>C Ala187Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
ACLNNIFM_00004 VFG005356 Streptococcal plasmin receptor/GAPDH 98.5 2.1e-185 10 345 0.9739 1.003 Adherence type I glyceraldehyde-3-phosphate dehydrogenase prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term