Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2554
  Reference Plasmid   1111525849852394_bin.9__k141_263112
  Reference Plasmid Size   7758
  Reference Plasmid GC Content   0.30
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047128 FPEDPCMA_00001 395 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -686T>G None
M0047129 FPEDPCMA_00001 397 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -684C>T None
M0047130 FPEDPCMA_00001 463 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -618A>G None
M0047131 FPEDPCMA_00001 809 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -272A>T None
M0047132 FPEDPCMA_00003 2102 4 Skin 0.57 protein_coding missense_variant MODERATE 46G>A Glu16Lys
M0047133 FPEDPCMA_00003 2108 4 Skin 0.57 protein_coding missense_variant MODERATE 52A>G Lys18Glu
M0047134 FPEDPCMA_00003 2122 4 Skin 0.57 protein_coding synonymous_variant LOW 66T>C Pro22Pro
M0047135 FPEDPCMA_00003 2144 6 Skin 0.86 protein_coding missense_variant MODERATE 88G>A Ala30Thr
M0047136 FPEDPCMA_00001 517 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -564G>A None
M0047137 FPEDPCMA_00001 529 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -552T>A None
M0047138 FPEDPCMA_00001 595 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -486C>T None
M0047139 FPEDPCMA_00001 706 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -375T>C None
M0047140 FPEDPCMA_00001 711 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -370G>T None
M0047141 FPEDPCMA_00001 855 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -226C>T None
M0047142 FPEDPCMA_00001 856 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -225G>A None
M0047143 FPEDPCMA_00001 876 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -205T>A None
M0047144 FPEDPCMA_00001 903 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -178G>T None
M0047145 FPEDPCMA_00001 907 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -174A>G None
M0047146 FPEDPCMA_00001 952 4 Skin 0.57 protein_coding upstream_gene_variant MODIFIER -129A>C None
M0047147 FPEDPCMA_00001 1049 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -32A>T None
M0047148 FPEDPCMA_00001 1176 3 Skin 0.43 protein_coding synonymous_variant LOW 96T>C Asp32Asp
M0047149 FPEDPCMA_00001 1179 3 Skin 0.43 protein_coding synonymous_variant LOW 99G>A Gln33Gln
M0047150 FPEDPCMA_00001 1182 4 Skin 0.57 protein_coding synonymous_variant LOW 102G>A Leu34Leu
M0047151 FPEDPCMA_00001 1197 3 Skin 0.43 protein_coding synonymous_variant LOW 117G>A Lys39Lys
M0047152 FPEDPCMA_00001 1209 3 Skin 0.43 protein_coding synonymous_variant LOW 129A>G Lys43Lys
M0047153 FPEDPCMA_00001 1281 4 Skin 0.57 protein_coding synonymous_variant LOW 201T>C Asn67Asn
M0047154 FPEDPCMA_00001 1284 4 Skin 0.57 protein_coding missense_variant MODERATE 204C>A Asp68Glu
M0047155 FPEDPCMA_00001 1287 4 Skin 0.57 protein_coding synonymous_variant LOW 207G>A Leu69Leu
M0047156 FPEDPCMA_00001 1354 3 Skin 0.43 protein_coding missense_variant MODERATE 274G>A Asp92Asn
M0047157 FPEDPCMA_00001 1365 3 Skin 0.43 protein_coding synonymous_variant LOW 285G>A Ser95Ser
M0047158 FPEDPCMA_00001 1426 3 Skin 0.43 protein_coding missense_variant MODERATE 346A>G Ser116Gly
M0047159 FPEDPCMA_00001 1461 3 Skin 0.43 protein_coding synonymous_variant LOW 381C>A Pro127Pro
M0047160 FPEDPCMA_00001 1465 3 Skin 0.43 protein_coding missense_variant MODERATE 385C>G Gln129Glu
M0047161 FPEDPCMA_00001 1468 5 Skin 0.71 protein_coding missense_variant MODERATE 388A>G Asn130Asp
M0047162 FPEDPCMA_00001 1471 3 Skin 0.43 protein_coding missense_variant MODERATE 391G>A Asp131Asn
M0047163 FPEDPCMA_00001 1498 4 Skin 0.57 protein_coding stop_gained HIGH 418C>T Arg140*
M0047164 FPEDPCMA_00002 1523 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -112A>G None
M0047165 FPEDPCMA_00002 1533 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -102C>T None
M0047166 FPEDPCMA_00002 1535 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -100G>A None
M0047167 FPEDPCMA_00002 1552 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -83T>G None
M0047168 FPEDPCMA_00002 1659 5 Skin 0.71 protein_coding synonymous_variant LOW 25C>T Leu9Leu
M0047169 FPEDPCMA_00002 1688 3 Skin 0.43 protein_coding synonymous_variant LOW 54A>G Glu18Glu
M0047170 FPEDPCMA_00002 1712 3 Skin 0.43 protein_coding synonymous_variant LOW 78A>G Leu26Leu
M0047171 FPEDPCMA_00002 1721 3 Skin 0.43 protein_coding synonymous_variant LOW 87T>A Arg29Arg
M0047172 FPEDPCMA_00002 1740 3 Skin 0.43 protein_coding missense_variant MODERATE 106A>G Ser36Gly
M0047173 FPEDPCMA_00002 1802 3 Skin 0.43 protein_coding synonymous_variant LOW 168A>G Val56Val
M0047174 FPEDPCMA_00002 1823 3 Skin 0.43 protein_coding synonymous_variant LOW 189T>C His63His
M0047175 FPEDPCMA_00002 1844 3 Skin 0.43 protein_coding synonymous_variant LOW 210A>G Ala70Ala
M0047176 FPEDPCMA_00002 1847 3 Skin 0.43 protein_coding synonymous_variant LOW 213A>G Thr71Thr
M0047177 FPEDPCMA_00002 1904 3 Skin 0.43 protein_coding synonymous_variant LOW 270G>A Lys90Lys
M0047178 FPEDPCMA_00002 1905 5 Skin 0.71 protein_coding synonymous_variant LOW 271T>C Leu91Leu
M0047179 FPEDPCMA_00003 2029 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -28G>A None
M0047180 FPEDPCMA_00003 2230 3 Skin 0.43 protein_coding synonymous_variant LOW 174G>A Glu58Glu
M0047181 FPEDPCMA_00003 2254 3 Skin 0.43 protein_coding synonymous_variant LOW 198A>C Val66Val
M0047182 FPEDPCMA_00003 2284 3 Skin 0.43 protein_coding synonymous_variant LOW 228G>T Gly76Gly
M0047183 FPEDPCMA_00003 2305 3 Skin 0.43 protein_coding synonymous_variant LOW 249T>A Val83Val
M0047184 FPEDPCMA_00003 2356 3 Skin 0.43 protein_coding synonymous_variant LOW 300T>G Gly100Gly
M0047185 FPEDPCMA_00003 2407 4 Skin 0.57 protein_coding synonymous_variant LOW 351A>G Ala117Ala
M0047186 FPEDPCMA_00003 2482 4 Skin 0.57 protein_coding synonymous_variant LOW 426T>C Pro142Pro






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term