Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2558
  Reference Plasmid   1111525849852445_bin.29__k141_259978
  Reference Plasmid Size   5289
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047194 BKCAIPAN_00001 682 3 Skin 0.75 protein_coding synonymous_variant LOW 1395G>A Val465Val
M0047195 BKCAIPAN_00001 820 3 Skin 0.75 protein_coding missense_variant MODERATE 1257C>G Asp419Glu
M0047196 BKCAIPAN_00001 823 3 Skin 0.75 protein_coding synonymous_variant LOW 1254T>G Thr418Thr
M0047197 BKCAIPAN_00001 1042 3 Skin 0.75 protein_coding synonymous_variant LOW 1035C>G Gly345Gly
M0047198 BKCAIPAN_00001 1045 3 Skin 0.75 protein_coding synonymous_variant LOW 1032C>T Asp344Asp
M0047199 BKCAIPAN_00001 1197 4 Skin 1.00 protein_coding missense_variant MODERATE 880C>A Pro294Thr
M0047200 BKCAIPAN_00001 1264 4 Skin 1.00 protein_coding synonymous_variant LOW 813A>G Glu271Glu
M0047201 BKCAIPAN_00001 1291 4 Skin 1.00 protein_coding synonymous_variant LOW 786A>G Val262Val
M0047202 BKCAIPAN_00001 1321 3 Skin 0.75 protein_coding synonymous_variant LOW 756T>G Gly252Gly
M0047203 BKCAIPAN_00001 1369 3 Skin 0.75 protein_coding synonymous_variant LOW 708C>T Ser236Ser
M0047204 BKCAIPAN_00001 1387 4 Skin 1.00 protein_coding synonymous_variant LOW 690A>G Lys230Lys
M0047205 BKCAIPAN_00001 1591 3 Skin 0.75 protein_coding synonymous_variant LOW 486C>T Arg162Arg
M0047206 BKCAIPAN_00001 1602 3 Skin 0.75 protein_coding synonymous_variant LOW 475T>C Leu159Leu
M0047207 BKCAIPAN_00001 1609 3 Skin 0.75 protein_coding synonymous_variant LOW 468C>G Gly156Gly
M0047208 BKCAIPAN_00001 1618 3 Skin 0.75 protein_coding synonymous_variant LOW 459T>C Asn153Asn
M0047209 BKCAIPAN_00001 1621 3 Skin 0.75 protein_coding synonymous_variant LOW 456T>C Cys152Cys
M0047210 BKCAIPAN_00001 1645 3 Skin 0.75 protein_coding synonymous_variant LOW 432G>C Gly144Gly
M0047211 BKCAIPAN_00001 1717 3 Skin 0.75 protein_coding synonymous_variant LOW 360A>G Leu120Leu
M0047212 BKCAIPAN_00001 1729 3 Skin 0.75 protein_coding synonymous_variant LOW 348A>T Pro116Pro
M0047213 BKCAIPAN_00001 1768 3 Skin 0.75 protein_coding synonymous_variant LOW 309C>T Ile103Ile
M0047214 BKCAIPAN_00001 1789 3 Skin 0.75 protein_coding synonymous_variant LOW 288C>T Ser96Ser
M0047215 BKCAIPAN_00001 1861 3 Skin 0.75 protein_coding synonymous_variant LOW 216C>T Ala72Ala
M0047216 BKCAIPAN_00002 2352 3 Skin 0.75 protein_coding missense_variant MODERATE 62A>G Asn21Ser
M0047217 BKCAIPAN_00002 2355 3 Skin 0.75 protein_coding missense_variant MODERATE 59T>A Val20Glu
M0047218 BKCAIPAN_00001 2497 4 Skin 1.00 protein_coding upstream_gene_variant MODIFIER -421C>T None
M0047219 BKCAIPAN_00001 2510 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -434A>G None
M0047220 BKCAIPAN_00001 2523 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -447G>T None
M0047221 BKCAIPAN_00003 2673 3 Skin 0.75 protein_coding synonymous_variant LOW 1047G>A Glu349Glu
M0047222 BKCAIPAN_00001 1015 3 Skin 0.75 protein_coding synonymous_variant LOW 1062G>T Gly354Gly
M0047223 BKCAIPAN_00002 2272 3 Skin 0.75 protein_coding missense_variant MODERATE 142C>G Pro48Ala
M0047224 BKCAIPAN_00002 2306 3 Skin 0.75 protein_coding synonymous_variant LOW 108C>G Leu36Leu
M0047225 BKCAIPAN_00002 2324 3 Skin 0.75 protein_coding synonymous_variant LOW 90A>T Pro30Pro
M0047226 BKCAIPAN_00002 2333 3 Skin 0.75 protein_coding synonymous_variant LOW 81C>T Tyr27Tyr
M0047227 BKCAIPAN_00003 2751 3 Skin 0.75 protein_coding synonymous_variant LOW 969G>A Arg323Arg
M0047228 BKCAIPAN_00003 2769 3 Skin 0.75 protein_coding synonymous_variant LOW 951T>C Asp317Asp
M0047229 BKCAIPAN_00003 2772 3 Skin 0.75 protein_coding synonymous_variant LOW 948T>C Ile316Ile
M0047230 BKCAIPAN_00003 2811 3 Skin 0.75 protein_coding synonymous_variant LOW 909C>A Thr303Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term