Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2577
  Reference Plasmid   1111525849853831_bin.4__k141_53756
  Reference Plasmid Size   40555
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047658 KALJPPGM_00007 4688 9 Skin 0.20 protein_coding synonymous_variant LOW 672C>T Asp224Asp
M0047659 KALJPPGM_00008 5911 4 Skin 0.09 protein_coding synonymous_variant LOW 927C>G Ala309Ala
M0047660 KALJPPGM_00009 6627 3 Skin 0.07 protein_coding missense_variant MODERATE 343C>G Leu115Val
M0047661 KALJPPGM_00010 7079 6 Skin 0.14 protein_coding synonymous_variant LOW 81A>C Pro27Pro
M0047662 KALJPPGM_00027 21277 4 Skin 0.09 protein_coding synonymous_variant LOW 1014C>G Val338Val
M0047663 KALJPPGM_00011 7765 5 Skin 0.11 protein_coding synonymous_variant LOW 1092T>G Ser364Ser
M0047664 KALJPPGM_00003 7252 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4833G>C None
M0047665 KALJPPGM_00003 7259 3 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4840T>C None
M0047666 KALJPPGM_00011 7473 4 Skin 0.09 protein_coding synonymous_variant LOW 1384C>T Leu462Leu
M0047667 KALJPPGM_00011 8341 3 Skin 0.07 protein_coding synonymous_variant LOW 516T>C Ser172Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant
KALJPPGM_00005 PHI:3118 PSPTO_2691 76.6 1.8e-96 1 248 0.9920 0.9763 eudicots bacterial speck (tomato) membrane protein, TerC family unaffected pathogenicity
KALJPPGM_00021 PHI:5468 modA 77.3 8.8e-107 1 255 1.0000 1.0000 rodents nosocomial infection part of molybdate transporter ModABC reduced virulence






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
KALJPPGM_00008 2.A.23.1.13 71.4 1.1e-146 4 401 0.9876 0.9614 2 Electrochemical Potential-driven Transporters 2.A Porters (uniporters, symporters, antiporters) 2.A.23 The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family