Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2582
  Reference Plasmid   1111525849853957_bin.36__k141_973421
  Reference Plasmid Size   65022
  Reference Plasmid GC Content   0.33
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047688 KGMJEOOI_00035 33687 8 Skin 0.10 protein_coding synonymous_variant LOW 183A>G Lys61Lys
M0047689 KGMJEOOI_00035 33690 6 Skin 0.07 protein_coding missense_variant MODERATE 186C>A Asn62Lys
M0047690 KGMJEOOI_00035 33930 7 Skin 0.09 protein_coding synonymous_variant LOW 426T>C Gly142Gly
M0047691 KGMJEOOI_00035 33937 9 Skin 0.11 protein_coding missense_variant MODERATE 433G>A Val145Ile
M0047692 KGMJEOOI_00035 34024 5 Skin 0.06 protein_coding missense_variant MODERATE 520C>T His174Tyr
M0047693 KGMJEOOI_00035 34047 5 Skin 0.06 protein_coding synonymous_variant LOW 543C>T Ala181Ala
M0047694 KGMJEOOI_00035 34050 5 Skin 0.06 protein_coding synonymous_variant LOW 546A>G Thr182Thr
M0047695 KGMJEOOI_00035 34071 5 Skin 0.06 protein_coding synonymous_variant LOW 567G>A Leu189Leu
M0047696 KGMJEOOI_00035 34074 5 Skin 0.06 protein_coding synonymous_variant LOW 570G>A Lys190Lys
M0047697 KGMJEOOI_00035 34083 5 Skin 0.06 protein_coding synonymous_variant LOW 579C>G Ser193Ser
M0047698 KGMJEOOI_00035 34086 5 Skin 0.06 protein_coding synonymous_variant LOW 582G>A Thr194Thr
M0047699 KGMJEOOI_00035 34087 5 Skin 0.06 protein_coding missense_variant MODERATE 583A>C Ile195Leu
M0047700 KGMJEOOI_00035 34203 7 Skin 0.09 protein_coding synonymous_variant LOW 699T>C Phe233Phe
M0047701 KGMJEOOI_00035 34260 7 Skin 0.09 protein_coding synonymous_variant LOW 756T>C Gly252Gly
M0047702 KGMJEOOI_00032 34532 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3953A>G None
M0047703 KGMJEOOI_00032 34538 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -3959C>T None
M0047704 KGMJEOOI_00036 35154 7 Skin 0.09 protein_coding synonymous_variant LOW 588G>A Leu196Leu
M0047705 KGMJEOOI_00036 35244 6 Skin 0.07 protein_coding synonymous_variant LOW 498T>A Ile166Ile
M0047706 KGMJEOOI_00036 35472 6 Skin 0.07 protein_coding synonymous_variant LOW 270T>C Gly90Gly
M0047707 KGMJEOOI_00036 35479 7 Skin 0.09 protein_coding missense_variant MODERATE 263G>A Arg88Lys
M0047708 KGMJEOOI_00036 35546 8 Skin 0.10 protein_coding synonymous_variant LOW 196T>C Leu66Leu
M0047709 KGMJEOOI_00036 35550 7 Skin 0.09 protein_coding synonymous_variant LOW 192T>C Val64Val
M0047710 KGMJEOOI_00036 35574 8 Skin 0.10 protein_coding synonymous_variant LOW 168G>A Leu56Leu
M0047711 KGMJEOOI_00036 35594 8 Skin 0.10 protein_coding missense_variant MODERATE 148A>G Ile50Val
M0047712 KGMJEOOI_00033 35747 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -3651C>A None
M0047713 KGMJEOOI_00033 35809 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -3713T>A None
M0047714 KGMJEOOI_00033 35894 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -3798A>G None
M0047715 KGMJEOOI_00033 36393 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4297T>C None
M0047716 KGMJEOOI_00003 2921 8 Skin 0.10 protein_coding missense_variant MODERATE 3691A>G Ile1231Val
M0047717 KGMJEOOI_00010 11669 4 Skin 0.05 protein_coding synonymous_variant LOW 363A>C Val121Val
M0047718 KGMJEOOI_00057 57392 13 Skin 0.16 protein_coding synonymous_variant LOW 351T>C Ser117Ser
M0047719 KGMJEOOI_00053 57853 14 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4571T>C None
M0047720 KGMJEOOI_00061 60245 11 Skin 0.14 protein_coding synonymous_variant LOW 525G>T Pro175Pro
M0047721 KGMJEOOI_00061 60423 11 Skin 0.14 protein_coding missense_variant MODERATE 347A>C Lys116Thr
M0047722 KGMJEOOI_00062 60986 3 Skin 0.04 protein_coding synonymous_variant LOW 201A>G Ser67Ser
M0047723 KGMJEOOI_00058 61442 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3254A>G None
M0047724 KGMJEOOI_00063 61595 9 Skin 0.11 protein_coding synonymous_variant LOW 153T>C Ile51Ile
M0047725 KGMJEOOI_00003 10773 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4162T>C None
M0047726 KGMJEOOI_00003 10785 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4174G>A None
M0047727 KGMJEOOI_00003 10790 6 Skin 0.07 protein_coding upstream_gene_variant MODIFIER -4179A>G None
M0047728 KGMJEOOI_00038 37710 15 Skin 0.19 protein_coding missense_variant MODERATE 234A>G Ile78Met
M0047729 KGMJEOOI_00038 37861 12 Skin 0.15 protein_coding missense_variant MODERATE 83T>C Ile28Thr
M0047730 KGMJEOOI_00042 39465 13 Skin 0.16 protein_coding missense_variant MODERATE 890C>T Pro297Leu
M0047731 KGMJEOOI_00064 61935 8 Skin 0.10 protein_coding missense_variant MODERATE 566T>C Ile189Thr
M0047732 KGMJEOOI_00064 62021 8 Skin 0.10 protein_coding synonymous_variant LOW 480T>C Gly160Gly
M0047733 KGMJEOOI_00064 62276 8 Skin 0.10 protein_coding synonymous_variant LOW 225A>T Thr75Thr
M0047734 KGMJEOOI_00068 63661 7 Skin 0.09 protein_coding missense_variant MODERATE 334A>C Thr112Pro
M0047735 KGMJEOOI_00006 9378 3 Skin 0.04 protein_coding synonymous_variant LOW 426A>C Ile142Ile
M0047736 KGMJEOOI_00006 9630 3 Skin 0.04 protein_coding synonymous_variant LOW 678G>A Leu226Leu
M0047737 KGMJEOOI_00006 9651 3 Skin 0.04 protein_coding synonymous_variant LOW 699T>C Leu233Leu
M0047738 KGMJEOOI_00006 9729 3 Skin 0.04 protein_coding synonymous_variant LOW 777G>A Gln259Gln
M0047739 KGMJEOOI_00003 9771 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3160G>A None
M0047740 KGMJEOOI_00007 9863 4 Skin 0.05 protein_coding missense_variant MODERATE 259T>C Cys87Arg
M0047741 KGMJEOOI_00007 9987 5 Skin 0.06 protein_coding synonymous_variant LOW 135C>T Gly45Gly
M0047742 KGMJEOOI_00007 10041 4 Skin 0.05 protein_coding synonymous_variant LOW 81T>C Ala27Ala
M0047743 KGMJEOOI_00007 10059 4 Skin 0.05 protein_coding synonymous_variant LOW 63T>C Phe21Phe
M0047744 KGMJEOOI_00003 10229 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3618T>C None
M0047745 KGMJEOOI_00008 10385 5 Skin 0.06 protein_coding missense_variant MODERATE 286A>G Thr96Ala
M0047746 KGMJEOOI_00008 10410 5 Skin 0.06 protein_coding missense_variant MODERATE 261A>T Lys87Asn
M0047747 KGMJEOOI_00003 11219 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -4608A>G None
M0047748 KGMJEOOI_00010 11426 4 Skin 0.05 protein_coding synonymous_variant LOW 120G>A Thr40Thr
M0047749 KGMJEOOI_00010 11491 4 Skin 0.05 protein_coding missense_variant MODERATE 185G>A Ser62Asn
M0047750 KGMJEOOI_00010 11593 4 Skin 0.05 protein_coding missense_variant MODERATE 287A>G His96Arg
M0047751 KGMJEOOI_00010 11345 4 Skin 0.05 protein_coding synonymous_variant LOW 39C>T His13His
M0047752 KGMJEOOI_00018 16289 14 Skin 0.17 protein_coding synonymous_variant LOW 672T>C Tyr224Tyr
M0047753 KGMJEOOI_00019 18298 6 Skin 0.07 protein_coding missense_variant MODERATE 817A>G Ile273Val
M0047754 KGMJEOOI_00021 19747 12 Skin 0.15 protein_coding synonymous_variant LOW 813A>T Ile271Ile
M0047755 KGMJEOOI_00017 20643 14 Skin 0.17 protein_coding upstream_gene_variant MODIFIER -4789T>G None
M0047756 KGMJEOOI_00022 20949 14 Skin 0.17 protein_coding synonymous_variant LOW 54C>T Asn18Asn
M0047757 KGMJEOOI_00018 16156 4 Skin 0.05 protein_coding missense_variant MODERATE 805T>A Ser269Thr
M0047758 KGMJEOOI_00025 23664 3 Skin 0.04 protein_coding missense_variant MODERATE 157A>G Ile53Val
M0047759 KGMJEOOI_00026 24087 3 Skin 0.04 protein_coding missense_variant MODERATE 502G>A Ala168Thr
M0047760 KGMJEOOI_00029 26691 4 Skin 0.05 protein_coding synonymous_variant LOW 339C>A Gly113Gly
M0047761 KGMJEOOI_00032 29995 4 Skin 0.05 protein_coding synonymous_variant LOW 585G>A Leu195Leu
M0047762 KGMJEOOI_00032 30409 14 Skin 0.17 protein_coding missense_variant MODERATE 171A>G Ile57Met
M0047763 KGMJEOOI_00033 31853 5 Skin 0.06 protein_coding missense_variant MODERATE 244G>A Asp82Asn
M0047764 KGMJEOOI_00031 32605 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4706A>G None
M0047765 KGMJEOOI_00038 37325 3 Skin 0.04 protein_coding missense_variant MODERATE 619G>A Asp207Asn
M0047766 KGMJEOOI_00042 39698 4 Skin 0.05 protein_coding synonymous_variant LOW 657C>T Ala219Ala
M0047767 KGMJEOOI_00043 41946 7 Skin 0.09 protein_coding missense_variant MODERATE 125A>G Glu42Gly
M0047768 KGMJEOOI_00028 26111 3 Skin 0.04 protein_coding missense_variant MODERATE 166T>C Ser56Pro
M0047769 KGMJEOOI_00028 26115 3 Skin 0.04 protein_coding synonymous_variant LOW 162T>C His54His
M0047770 KGMJEOOI_00029 27023 3 Skin 0.04 protein_coding missense_variant MODERATE 7G>A Val3Ile
M0047771 KGMJEOOI_00024 27117 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3676A>G None
M0047772 KGMJEOOI_00032 28383 3 Skin 0.04 protein_coding missense_variant MODERATE 2197A>G Lys733Glu
M0047773 KGMJEOOI_00032 28399 3 Skin 0.04 protein_coding synonymous_variant LOW 2181C>T Tyr727Tyr
M0047774 KGMJEOOI_00032 28456 3 Skin 0.04 protein_coding synonymous_variant LOW 2124C>T Gly708Gly
M0047775 KGMJEOOI_00032 28617 3 Skin 0.04 protein_coding missense_variant MODERATE 1963G>A Glu655Lys
M0047776 KGMJEOOI_00032 29983 3 Skin 0.04 protein_coding synonymous_variant LOW 597T>C Asp199Asp
M0047777 KGMJEOOI_00032 29992 3 Skin 0.04 protein_coding synonymous_variant LOW 588G>A Ala196Ala
M0047778 KGMJEOOI_00033 31569 3 Skin 0.04 protein_coding synonymous_variant LOW 528G>A Val176Val
M0047779 KGMJEOOI_00033 31852 3 Skin 0.04 protein_coding missense_variant MODERATE 245A>G Asp82Gly
M0047780 KGMJEOOI_00032 33228 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -2649G>A None
M0047781 KGMJEOOI_00032 33255 9 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -2676A>G None
M0047782 KGMJEOOI_00032 33449 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2870A>G None
M0047783 KGMJEOOI_00038 36792 4 Skin 0.05 protein_coding synonymous_variant LOW 1152A>G Gln384Gln
M0047784 KGMJEOOI_00038 36855 3 Skin 0.04 protein_coding synonymous_variant LOW 1089T>G Gly363Gly
M0047785 KGMJEOOI_00038 37599 4 Skin 0.05 protein_coding synonymous_variant LOW 345C>T Cys115Cys
M0047786 KGMJEOOI_00038 37617 4 Skin 0.05 protein_coding synonymous_variant LOW 327T>C Phe109Phe
M0047787 KGMJEOOI_00038 37716 4 Skin 0.05 protein_coding synonymous_variant LOW 228G>A Leu76Leu
M0047788 KGMJEOOI_00040 38993 3 Skin 0.04 protein_coding missense_variant MODERATE 119T>A Ile40Asn
M0047789 KGMJEOOI_00042 39394 3 Skin 0.04 protein_coding missense_variant MODERATE 961C>G His321Asp
M0047790 KGMJEOOI_00042 39412 3 Skin 0.04 protein_coding missense_variant MODERATE 943G>A Val315Ile
M0047791 KGMJEOOI_00042 40056 3 Skin 0.04 protein_coding missense_variant MODERATE 299T>C Leu100Pro
M0047792 KGMJEOOI_00031 32793 4 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4894A>C None
M0047793 KGMJEOOI_00056 56626 4 Skin 0.05 protein_coding missense_variant MODERATE 1405C>G Leu469Val
M0047794 KGMJEOOI_00056 56682 3 Skin 0.04 protein_coding synonymous_variant LOW 1461T>A Ile487Ile
M0047795 KGMJEOOI_00007 13647 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3526G>A None
M0047796 KGMJEOOI_00032 33119 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2540A>G None
M0047797 KGMJEOOI_00032 33122 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2543T>G None
M0047798 KGMJEOOI_00032 33206 7 Skin 0.09 protein_coding upstream_gene_variant MODIFIER -2627T>C None
M0047799 KGMJEOOI_00034 33351 7 Skin 0.09 protein_coding missense_variant MODERATE 87G>A Met29Ile
M0047800 KGMJEOOI_00034 33367 8 Skin 0.10 protein_coding missense_variant MODERATE 71T>A Ile24Lys
M0047801 KGMJEOOI_00032 33456 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2877T>A None
M0047802 KGMJEOOI_00032 33459 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2880G>A None
M0047803 KGMJEOOI_00032 33474 5 Skin 0.06 protein_coding upstream_gene_variant MODIFIER -2895T>A None
M0047804 KGMJEOOI_00035 33570 5 Skin 0.06 protein_coding synonymous_variant LOW 66G>A Thr22Thr
M0047805 KGMJEOOI_00035 33572 5 Skin 0.06 protein_coding missense_variant MODERATE 68A>T Tyr23Phe
M0047806 KGMJEOOI_00035 33591 5 Skin 0.06 protein_coding synonymous_variant LOW 87G>A Glu29Glu
M0047807 KGMJEOOI_00038 36963 3 Skin 0.04 protein_coding synonymous_variant LOW 981C>A Ser327Ser
M0047808 KGMJEOOI_00038 37368 4 Skin 0.05 protein_coding synonymous_variant LOW 576T>C Ile192Ile
M0047809 KGMJEOOI_00039 37972 3 Skin 0.04 protein_coding missense_variant MODERATE 570A>T Lys190Asn
M0047810 KGMJEOOI_00039 37993 3 Skin 0.04 protein_coding synonymous_variant LOW 549G>A Val183Val
M0047811 KGMJEOOI_00039 38134 4 Skin 0.05 protein_coding synonymous_variant LOW 408A>G Leu136Leu
M0047812 KGMJEOOI_00039 38182 3 Skin 0.04 protein_coding synonymous_variant LOW 360A>T Thr120Thr
M0047813 KGMJEOOI_00012 14018 4 Skin 0.05 protein_coding synonymous_variant LOW 279C>T Asp93Asp
M0047814 KGMJEOOI_00012 14024 4 Skin 0.05 protein_coding synonymous_variant LOW 285A>G Glu95Glu
M0047815 KGMJEOOI_00032 29871 4 Skin 0.05 protein_coding missense_variant MODERATE 709G>A Ala237Thr
M0047816 KGMJEOOI_00007 9938 3 Skin 0.04 protein_coding missense_variant MODERATE 184C>T Arg62Cys
M0047817 KGMJEOOI_00003 10672 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4061T>G None
M0047818 KGMJEOOI_00031 32483 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4584T>A None
M0047819 KGMJEOOI_00031 32512 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4613G>C None
M0047820 KGMJEOOI_00031 32527 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4628A>T None
M0047821 KGMJEOOI_00031 32553 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4654C>T None
M0047822 KGMJEOOI_00032 32994 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -2415C>A None
M0047823 KGMJEOOI_00032 32998 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -2419C>T None
M0047824 KGMJEOOI_00056 56535 3 Skin 0.04 protein_coding synonymous_variant LOW 1314T>C Ile438Ile
M0047825 KGMJEOOI_00053 56811 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -3529T>G None
M0047826 KGMJEOOI_00053 57745 3 Skin 0.04 protein_coding upstream_gene_variant MODIFIER -4463A>G None
M0047827 KGMJEOOI_00057 57112 3 Skin 0.04 protein_coding missense_variant MODERATE 71C>T Ala24Val
M0047828 KGMJEOOI_00059 58615 3 Skin 0.04 protein_coding missense_variant MODERATE 300A>T Arg100Ser
M0047829 KGMJEOOI_00003 5256 3 Skin 0.04 protein_coding synonymous_variant LOW 1356T>C His452His
M0047830 KGMJEOOI_00003 5270 3 Skin 0.04 protein_coding missense_variant MODERATE 1342G>T Asp448Tyr
M0047831 KGMJEOOI_00010 12427 3 Skin 0.04 protein_coding missense_variant MODERATE 1121T>C Met374Thr
M0047832 KGMJEOOI_00012 13784 3 Skin 0.04 protein_coding synonymous_variant LOW 45A>C Ile15Ile
M0047833 KGMJEOOI_00012 13791 3 Skin 0.04 protein_coding missense_variant MODERATE 52G>A Ala18Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition
KGMJEOOI_00018 VFG043453 SE2319 85 2.2e-155 1 333 1.0 1.0278 Adherence autolysin/adhesin Aae prediction







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
KGMJEOOI_00010 UZX46690.1|GT4 99.8 0 1 500 1 1
KGMJEOOI_00018 UZX46695.1|CBM50 100 1.82e-212 1 333 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term