Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2585
  Reference Plasmid   1111525849854017_bin.12__k141_94516
  Reference Plasmid Size   16316
  Reference Plasmid GC Content   0.40
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047836 EDAAHACF_00010 11093 3 Skin 0.50 protein_coding synonymous_variant LOW 75T>C Gly25Gly
M0047837 EDAAHACF_00010 11136 3 Skin 0.50 protein_coding missense_variant MODERATE 32T>C Val11Ala
M0047838 EDAAHACF_00006 11238 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3497G>A None
M0047839 EDAAHACF_00006 11272 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3531C>A None
M0047840 EDAAHACF_00006 11288 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3547C>T None
M0047841 EDAAHACF_00006 11308 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -3567A>G None
M0047842 EDAAHACF_00011 11336 3 Skin 0.50 protein_coding synonymous_variant LOW 585A>G Val195Val
M0047843 EDAAHACF_00011 11390 3 Skin 0.50 protein_coding synonymous_variant LOW 531C>T Phe177Phe
M0047844 EDAAHACF_00012 12069 3 Skin 0.50 protein_coding missense_variant MODERATE 115A>G Ser39Gly
M0047845 EDAAHACF_00012 12113 3 Skin 0.50 protein_coding missense_variant MODERATE 71T>C Leu24Ser
M0047846 EDAAHACF_00013 12510 3 Skin 0.50 protein_coding synonymous_variant LOW 99A>G Thr33Thr
M0047847 EDAAHACF_00013 12532 3 Skin 0.50 protein_coding missense_variant MODERATE 77C>T Thr26Met
M0047848 EDAAHACF_00013 12603 3 Skin 0.50 protein_coding synonymous_variant LOW 6T>C Thr2Thr
M0047849 EDAAHACF_00014 13059 3 Skin 0.50 protein_coding synonymous_variant LOW 237A>T Gly79Gly
M0047850 EDAAHACF_00014 13065 3 Skin 0.50 protein_coding synonymous_variant LOW 243C>T Ser81Ser
M0047851 EDAAHACF_00015 13312 3 Skin 0.50 protein_coding synonymous_variant LOW 1596C>T Tyr532Tyr
M0047852 EDAAHACF_00015 13321 5 Skin 0.83 protein_coding synonymous_variant LOW 1587T>C Tyr529Tyr
M0047853 EDAAHACF_00015 13366 5 Skin 0.83 protein_coding synonymous_variant LOW 1542T>C Phe514Phe
M0047854 EDAAHACF_00015 13372 5 Skin 0.83 protein_coding synonymous_variant LOW 1536G>A Leu512Leu
M0047855 EDAAHACF_00015 13575 3 Skin 0.50 protein_coding synonymous_variant LOW 1333C>T Leu445Leu
M0047856 EDAAHACF_00015 13591 3 Skin 0.50 protein_coding synonymous_variant LOW 1317G>A Gln439Gln
M0047857 EDAAHACF_00015 13666 3 Skin 0.50 protein_coding synonymous_variant LOW 1242T>C Ile414Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term