Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2586
  Reference Plasmid   1111525849854017_bin.13__k141_173949
  Reference Plasmid Size   5518
  Reference Plasmid GC Content   0.42
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0047858 KCEMPKMI_00002 745 3 Skin 0.60 protein_coding synonymous_variant LOW 87T>C Asn29Asn
M0047859 KCEMPKMI_00002 820 4 Skin 0.80 protein_coding synonymous_variant LOW 12T>A Pro4Pro
M0047860 KCEMPKMI_00001 853 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -444G>A None
M0047861 KCEMPKMI_00001 949 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -540G>T None
M0047862 KCEMPKMI_00001 956 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -547A>G None
M0047863 KCEMPKMI_00003 1113 3 Skin 0.60 protein_coding synonymous_variant LOW 288A>G Lys96Lys
M0047864 KCEMPKMI_00003 1189 3 Skin 0.60 protein_coding missense_variant MODERATE 212A>C Lys71Thr
M0047865 KCEMPKMI_00004 1433 4 Skin 0.80 protein_coding synonymous_variant LOW 1554C>T Ile518Ile
M0047866 KCEMPKMI_00004 1481 4 Skin 0.80 protein_coding synonymous_variant LOW 1506A>C Ala502Ala
M0047867 KCEMPKMI_00004 1508 3 Skin 0.60 protein_coding synonymous_variant LOW 1479C>T Asp493Asp
M0047868 KCEMPKMI_00004 1526 3 Skin 0.60 protein_coding synonymous_variant LOW 1461T>C His487His
M0047869 KCEMPKMI_00004 1631 3 Skin 0.60 protein_coding synonymous_variant LOW 1356G>A Glu452Glu
M0047870 KCEMPKMI_00004 1832 4 Skin 0.80 protein_coding synonymous_variant LOW 1155C>A Thr385Thr
M0047871 KCEMPKMI_00004 2087 3 Skin 0.60 protein_coding synonymous_variant LOW 900C>T Ile300Ile
M0047872 KCEMPKMI_00003 1298 3 Skin 0.60 protein_coding missense_variant MODERATE 103A>G Asn35Asp
M0047873 KCEMPKMI_00003 1304 3 Skin 0.60 protein_coding missense_variant MODERATE 97G>A Val33Met
M0047874 KCEMPKMI_00004 1787 3 Skin 0.60 protein_coding synonymous_variant LOW 1200C>T Leu400Leu
M0047875 KCEMPKMI_00004 1829 3 Skin 0.60 protein_coding synonymous_variant LOW 1158T>C Gly386Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term