Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2590
  Reference Plasmid   1111525849854152_bin.51__k141_106495
  Reference Plasmid Size   21754
  Reference Plasmid GC Content   0.67
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048281 DCLCOPFL_00001 1321 6 Skin 0.22 protein_coding missense_variant MODERATE 532C>G Pro178Ala
M0048282 DCLCOPFL_00001 1501 6 Skin 0.22 protein_coding synonymous_variant LOW 352C>T Leu118Leu
M0048283 DCLCOPFL_00001 1502 6 Skin 0.22 protein_coding synonymous_variant LOW 351A>G Glu117Glu
M0048284 DCLCOPFL_00001 1544 10 Skin 0.37 protein_coding synonymous_variant LOW 309T>C Ser103Ser
M0048285 DCLCOPFL_00001 1550 3 Skin 0.11 protein_coding synonymous_variant LOW 303G>A Ala101Ala
M0048286 DCLCOPFL_00002 1891 9 Skin 0.33 protein_coding synonymous_variant LOW 1164C>A Gly388Gly
M0048287 DCLCOPFL_00002 2020 5 Skin 0.19 protein_coding synonymous_variant LOW 1035C>G Thr345Thr
M0048288 DCLCOPFL_00002 2141 5 Skin 0.19 protein_coding missense_variant MODERATE 914G>T Gly305Val
M0048289 DCLCOPFL_00002 2164 9 Skin 0.33 protein_coding synonymous_variant LOW 891A>G Ala297Ala
M0048290 DCLCOPFL_00002 2233 5 Skin 0.19 protein_coding synonymous_variant LOW 822G>C Ser274Ser
M0048291 DCLCOPFL_00002 2247 9 Skin 0.33 protein_coding missense_variant MODERATE 808G>A Gly270Arg
M0048292 DCLCOPFL_00002 2249 9 Skin 0.33 protein_coding missense_variant MODERATE 806C>T Ala269Val
M0048293 DCLCOPFL_00002 2398 9 Skin 0.33 protein_coding synonymous_variant LOW 657T>C Ser219Ser
M0048294 DCLCOPFL_00002 2474 6 Skin 0.22 protein_coding missense_variant MODERATE 581A>G Asn194Ser
M0048295 DCLCOPFL_00002 2475 6 Skin 0.22 protein_coding missense_variant MODERATE 580A>C Asn194His
M0048296 DCLCOPFL_00002 2476 6 Skin 0.22 protein_coding synonymous_variant LOW 579T>C Cys193Cys
M0048297 DCLCOPFL_00002 2482 6 Skin 0.22 protein_coding synonymous_variant LOW 573C>T Gly191Gly
M0048298 DCLCOPFL_00002 2487 7 Skin 0.26 protein_coding missense_variant MODERATE 568A>G Asn190Asp
M0048299 DCLCOPFL_00002 2488 7 Skin 0.26 protein_coding synonymous_variant LOW 567A>G Val189Val
M0048300 DCLCOPFL_00002 2494 9 Skin 0.33 protein_coding missense_variant MODERATE 561T>G Asp187Glu
M0048301 DCLCOPFL_00002 2497 9 Skin 0.33 protein_coding synonymous_variant LOW 558A>C Ala186Ala
M0048302 DCLCOPFL_00002 2684 8 Skin 0.30 protein_coding missense_variant MODERATE 371C>T Ala124Val
M0048303 DCLCOPFL_00002 2704 8 Skin 0.30 protein_coding synonymous_variant LOW 351A>G Lys117Lys
M0048304 DCLCOPFL_00002 2780 9 Skin 0.33 protein_coding missense_variant MODERATE 275A>G His92Arg
M0048305 DCLCOPFL_00002 2941 7 Skin 0.26 protein_coding missense_variant MODERATE 114G>T Met38Ile
M0048306 DCLCOPFL_00003 3081 6 Skin 0.22 protein_coding missense_variant MODERATE 785C>A Ala262Glu
M0048307 DCLCOPFL_00003 3467 5 Skin 0.19 protein_coding missense_variant MODERATE 399C>G Phe133Leu
M0048308 DCLCOPFL_00003 3474 4 Skin 0.15 protein_coding missense_variant MODERATE 392T>G Met131Arg
M0048309 DCLCOPFL_00003 3496 5 Skin 0.19 protein_coding missense_variant MODERATE 370C>T Arg124Trp
M0048310 DCLCOPFL_00003 3501 5 Skin 0.19 protein_coding missense_variant MODERATE 365T>C Leu122Pro
M0048311 DCLCOPFL_00003 3858 5 Skin 0.19 protein_coding missense_variant MODERATE 8C>A Ala3Glu
M0048312 DCLCOPFL_00004 3935 4 Skin 0.15 protein_coding missense_variant MODERATE 845C>G Thr282Ser
M0048313 DCLCOPFL_00004 3949 5 Skin 0.19 protein_coding synonymous_variant LOW 831G>C Pro277Pro
M0048314 DCLCOPFL_00004 3954 3 Skin 0.11 protein_coding missense_variant MODERATE 826G>A Ala276Thr
M0048315 DCLCOPFL_00004 3973 5 Skin 0.19 protein_coding synonymous_variant LOW 807G>C Gly269Gly
M0048316 DCLCOPFL_00004 3979 5 Skin 0.19 protein_coding synonymous_variant LOW 801C>A Ile267Ile
M0048317 DCLCOPFL_00004 3982 5 Skin 0.19 protein_coding missense_variant MODERATE 798A>C Arg266Ser
M0048318 DCLCOPFL_00004 3988 5 Skin 0.19 protein_coding missense_variant MODERATE 792A>C Arg264Ser
M0048319 DCLCOPFL_00004 3990 5 Skin 0.19 protein_coding synonymous_variant LOW 790A>C Arg264Arg
M0048320 DCLCOPFL_00004 3991 5 Skin 0.19 protein_coding synonymous_variant LOW 789C>G Arg263Arg
M0048321 DCLCOPFL_00004 3993 5 Skin 0.19 protein_coding missense_variant MODERATE 787C>A Arg263Ser
M0048322 DCLCOPFL_00004 3994 5 Skin 0.19 protein_coding synonymous_variant LOW 786C>G Ala262Ala
M0048323 DCLCOPFL_00004 4017 7 Skin 0.26 protein_coding missense_variant MODERATE 763A>C Met255Leu
M0048324 DCLCOPFL_00004 4019 7 Skin 0.26 protein_coding missense_variant MODERATE 761C>G Ala254Gly
M0048325 DCLCOPFL_00004 4036 7 Skin 0.26 protein_coding synonymous_variant LOW 744T>C Gly248Gly
M0048326 DCLCOPFL_00004 4042 7 Skin 0.26 protein_coding synonymous_variant LOW 738G>C Pro246Pro
M0048327 DCLCOPFL_00004 4054 7 Skin 0.26 protein_coding synonymous_variant LOW 726T>C Ser242Ser
M0048328 DCLCOPFL_00004 4055 7 Skin 0.26 protein_coding missense_variant MODERATE 725G>C Ser242Thr
M0048329 DCLCOPFL_00004 4056 7 Skin 0.26 protein_coding missense_variant MODERATE 724A>T Ser242Cys
M0048330 DCLCOPFL_00004 4057 7 Skin 0.26 protein_coding synonymous_variant LOW 723C>G Thr241Thr
M0048331 DCLCOPFL_00004 4240 6 Skin 0.22 protein_coding synonymous_variant LOW 540A>C Gly180Gly
M0048332 DCLCOPFL_00001 545 4 Skin 0.15 protein_coding synonymous_variant LOW 1308C>T Ile436Ile
M0048333 DCLCOPFL_00001 657 9 Skin 0.33 protein_coding missense_variant MODERATE 1196C>G Thr399Ser
M0048334 DCLCOPFL_00001 1007 9 Skin 0.33 protein_coding synonymous_variant LOW 846A>G Pro282Pro
M0048335 DCLCOPFL_00001 1511 4 Skin 0.15 protein_coding synonymous_variant LOW 342A>G Glu114Glu
M0048336 DCLCOPFL_00001 1514 4 Skin 0.15 protein_coding synonymous_variant LOW 339G>C Val113Val
M0048337 DCLCOPFL_00001 1515 4 Skin 0.15 protein_coding missense_variant MODERATE 338T>C Val113Ala
M0048338 DCLCOPFL_00001 1517 4 Skin 0.15 protein_coding synonymous_variant LOW 336C>G Arg112Arg
M0048339 DCLCOPFL_00001 1589 4 Skin 0.15 protein_coding synonymous_variant LOW 264A>G Leu88Leu
M0048340 DCLCOPFL_00002 1962 3 Skin 0.11 protein_coding missense_variant MODERATE 1093G>C Ala365Pro
M0048341 DCLCOPFL_00002 1963 7 Skin 0.26 protein_coding synonymous_variant LOW 1092A>G Val364Val
M0048342 DCLCOPFL_00002 2451 3 Skin 0.11 protein_coding missense_variant MODERATE 604G>T Ala202Ser
M0048343 DCLCOPFL_00004 4531 6 Skin 0.22 protein_coding synonymous_variant LOW 249G>C Ala83Ala
M0048344 DCLCOPFL_00004 4534 6 Skin 0.22 protein_coding synonymous_variant LOW 246T>C Asp82Asp
M0048345 DCLCOPFL_00004 4537 6 Skin 0.22 protein_coding synonymous_variant LOW 243G>C Ala81Ala
M0048346 DCLCOPFL_00004 4539 6 Skin 0.22 protein_coding missense_variant MODERATE 241G>A Ala81Thr
M0048347 DCLCOPFL_00004 4555 6 Skin 0.22 protein_coding synonymous_variant LOW 225T>C Leu75Leu
M0048348 DCLCOPFL_00004 4565 6 Skin 0.22 protein_coding missense_variant MODERATE 215T>C Ile72Thr
M0048349 DCLCOPFL_00004 4602 4 Skin 0.15 protein_coding synonymous_variant LOW 178T>C Leu60Leu
M0048350 DCLCOPFL_00004 4603 4 Skin 0.15 protein_coding synonymous_variant LOW 177T>C Ser59Ser
M0048351 DCLCOPFL_00004 4663 4 Skin 0.15 protein_coding synonymous_variant LOW 117T>C Asp39Asp
M0048352 DCLCOPFL_00005 4783 4 Skin 0.15 protein_coding missense_variant MODERATE 449A>G Gln150Arg
M0048353 DCLCOPFL_00005 4785 4 Skin 0.15 protein_coding missense_variant MODERATE 447C>G Phe149Leu
M0048354 DCLCOPFL_00005 4811 5 Skin 0.19 protein_coding missense_variant MODERATE 421A>G Ile141Val
M0048355 DCLCOPFL_00005 5050 7 Skin 0.26 protein_coding missense_variant MODERATE 182G>A Arg61His
M0048356 DCLCOPFL_00005 5142 8 Skin 0.30 protein_coding synonymous_variant LOW 90T>C Ser30Ser
M0048357 DCLCOPFL_00005 5213 8 Skin 0.30 protein_coding missense_variant MODERATE 19A>G Thr7Ala
M0048358 DCLCOPFL_00006 5264 7 Skin 0.26 protein_coding synonymous_variant LOW 270C>G Pro90Pro
M0048359 DCLCOPFL_00007 5634 7 Skin 0.26 protein_coding synonymous_variant LOW 1620T>C Asp540Asp
M0048360 DCLCOPFL_00007 6382 4 Skin 0.15 protein_coding missense_variant MODERATE 872C>A Ala291Glu
M0048361 DCLCOPFL_00007 7191 5 Skin 0.19 protein_coding synonymous_variant LOW 63C>T Gly21Gly
M0048362 DCLCOPFL_00007 7221 5 Skin 0.19 protein_coding synonymous_variant LOW 33T>C Ala11Ala
M0048363 DCLCOPFL_00007 7239 7 Skin 0.26 protein_coding synonymous_variant LOW 15T>C Asp5Asp
M0048364 DCLCOPFL_00008 7567 7 Skin 0.26 protein_coding synonymous_variant LOW 204G>C Leu68Leu
M0048365 DCLCOPFL_00008 7854 4 Skin 0.15 protein_coding missense_variant MODERATE 491G>C Gly164Ala
M0048366 DCLCOPFL_00008 8009 7 Skin 0.26 protein_coding missense_variant MODERATE 646G>C Gly216Arg
M0048367 DCLCOPFL_00009 8427 7 Skin 0.26 protein_coding synonymous_variant LOW 993T>C Ser331Ser
M0048368 DCLCOPFL_00009 8499 3 Skin 0.11 protein_coding synonymous_variant LOW 921T>C Ala307Ala
M0048369 DCLCOPFL_00009 8502 3 Skin 0.11 protein_coding synonymous_variant LOW 918C>T Ala306Ala
M0048370 DCLCOPFL_00009 8592 8 Skin 0.30 protein_coding synonymous_variant LOW 828T>C Ile276Ile
M0048371 DCLCOPFL_00009 8625 5 Skin 0.19 protein_coding synonymous_variant LOW 795T>G Leu265Leu
M0048372 DCLCOPFL_00009 8760 8 Skin 0.30 protein_coding synonymous_variant LOW 660A>C Thr220Thr
M0048373 DCLCOPFL_00009 9384 8 Skin 0.30 protein_coding synonymous_variant LOW 36T>C Thr12Thr
M0048374 DCLCOPFL_00009 9398 7 Skin 0.26 protein_coding missense_variant MODERATE 22A>G Thr8Ala
M0048375 DCLCOPFL_00004 9458 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4679C>T None
M0048376 DCLCOPFL_00004 9459 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4680T>G None
M0048377 DCLCOPFL_00004 9476 7 Skin 0.26 protein_coding upstream_gene_variant MODIFIER -4697T>G None
M0048378 DCLCOPFL_00005 4980 3 Skin 0.11 protein_coding synonymous_variant LOW 252T>C His84His
M0048379 DCLCOPFL_00001 5556 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -3704G>A None
M0048380 DCLCOPFL_00001 213 3 Skin 0.11 protein_coding downstream_gene_variant MODIFIER *68T>G None
M0048381 DCLCOPFL_00001 214 3 Skin 0.11 protein_coding downstream_gene_variant MODIFIER *67C>G None
M0048382 DCLCOPFL_00001 464 4 Skin 0.15 protein_coding synonymous_variant LOW 1389C>T Ile463Ile
M0048383 DCLCOPFL_00001 1358 7 Skin 0.26 protein_coding synonymous_variant LOW 495T>G Val165Val
M0048384 DCLCOPFL_00002 2048 3 Skin 0.11 protein_coding missense_variant MODERATE 1007A>G Asn336Ser
M0048385 DCLCOPFL_00001 361 3 Skin 0.11 protein_coding missense_variant MODERATE 1492C>A His498Asn
M0048386 DCLCOPFL_00001 390 3 Skin 0.11 protein_coding missense_variant MODERATE 1463C>T Ala488Val
M0048387 DCLCOPFL_00001 586 4 Skin 0.15 protein_coding synonymous_variant LOW 1267C>T Leu423Leu
M0048388 DCLCOPFL_00001 587 4 Skin 0.15 protein_coding synonymous_variant LOW 1266A>G Gln422Gln
M0048389 DCLCOPFL_00001 722 3 Skin 0.11 protein_coding synonymous_variant LOW 1131G>C Leu377Leu
M0048390 DCLCOPFL_00001 1368 3 Skin 0.11 protein_coding missense_variant MODERATE 485A>G His162Arg
M0048391 DCLCOPFL_00001 1408 3 Skin 0.11 protein_coding synonymous_variant LOW 445C>T Leu149Leu
M0048392 DCLCOPFL_00004 4490 4 Skin 0.15 protein_coding missense_variant MODERATE 290A>G Gln97Arg
M0048393 DCLCOPFL_00007 6568 4 Skin 0.15 protein_coding missense_variant MODERATE 686A>G Asp229Gly
M0048394 DCLCOPFL_00007 6570 4 Skin 0.15 protein_coding synonymous_variant LOW 684G>A Lys228Lys
M0048395 DCLCOPFL_00008 7884 5 Skin 0.19 protein_coding missense_variant MODERATE 521T>A Leu174Gln
M0048396 DCLCOPFL_00004 9533 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4754G>C None
M0048397 DCLCOPFL_00004 9631 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4852G>T None
M0048398 DCLCOPFL_00010 9892 5 Skin 0.19 protein_coding synonymous_variant LOW 63G>A Val21Val
M0048399 DCLCOPFL_00005 9987 6 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4756C>T None
M0048400 DCLCOPFL_00005 10012 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4781G>A None
M0048401 DCLCOPFL_00005 10053 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4822C>G None
M0048402 DCLCOPFL_00005 10127 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4896T>G None
M0048403 DCLCOPFL_00005 10147 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4916G>C None
M0048404 DCLCOPFL_00006 10370 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4837A>G None
M0048405 DCLCOPFL_00006 10397 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4864T>C None
M0048406 DCLCOPFL_00006 10414 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4881A>G None
M0048407 DCLCOPFL_00006 10433 4 Skin 0.15 protein_coding upstream_gene_variant MODIFIER -4900T>C None
M0048408 DCLCOPFL_00011 10522 6 Skin 0.22 protein_coding missense_variant MODERATE 820A>G Ser274Gly
M0048409 DCLCOPFL_00011 11081 5 Skin 0.19 protein_coding synonymous_variant LOW 261G>A Leu87Leu
M0048410 DCLCOPFL_00007 11372 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4119A>G None
M0048411 DCLCOPFL_00007 11456 6 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -4203T>C None
M0048412 DCLCOPFL_00007 11470 8 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -4217G>C None
M0048413 DCLCOPFL_00012 12209 7 Skin 0.26 protein_coding synonymous_variant LOW 729T>C His243His
M0048414 DCLCOPFL_00012 12396 6 Skin 0.22 protein_coding missense_variant MODERATE 916A>G Ile306Val
M0048415 DCLCOPFL_00012 12398 5 Skin 0.19 protein_coding synonymous_variant LOW 918C>T Ile306Ile
M0048416 DCLCOPFL_00012 12401 3 Skin 0.11 protein_coding synonymous_variant LOW 921C>G Pro307Pro
M0048417 DCLCOPFL_00014 13723 5 Skin 0.19 protein_coding missense_variant MODERATE 653A>G Lys218Arg
M0048418 DCLCOPFL_00009 13765 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4346C>G None
M0048419 DCLCOPFL_00015 13971 8 Skin 0.30 protein_coding synonymous_variant LOW 99A>G Glu33Glu
M0048420 DCLCOPFL_00015 14052 8 Skin 0.30 protein_coding synonymous_variant LOW 180T>C Tyr60Tyr
M0048421 DCLCOPFL_00015 14181 4 Skin 0.15 protein_coding synonymous_variant LOW 309A>G Gln103Gln
M0048422 DCLCOPFL_00015 14184 3 Skin 0.11 protein_coding synonymous_variant LOW 312C>T Asp104Asp
M0048423 DCLCOPFL_00015 14379 4 Skin 0.15 protein_coding synonymous_variant LOW 507T>A Gly169Gly
M0048424 DCLCOPFL_00015 14754 8 Skin 0.30 protein_coding synonymous_variant LOW 882T>C Arg294Arg
M0048425 DCLCOPFL_00015 14973 8 Skin 0.30 protein_coding synonymous_variant LOW 1101T>C Ala367Ala
M0048426 DCLCOPFL_00015 14976 3 Skin 0.11 protein_coding synonymous_variant LOW 1104A>G Glu368Glu
M0048427 DCLCOPFL_00016 15509 5 Skin 0.19 protein_coding synonymous_variant LOW 807C>T Ile269Ile
M0048428 DCLCOPFL_00017 16605 3 Skin 0.11 protein_coding missense_variant MODERATE 239G>T Trp80Leu
M0048429 DCLCOPFL_00017 16606 3 Skin 0.11 protein_coding missense_variant MODERATE 240G>C Trp80Cys
M0048430 DCLCOPFL_00017 16607 3 Skin 0.11 protein_coding missense_variant MODERATE 241T>C Ser81Pro
M0048431 DCLCOPFL_00017 16608 3 Skin 0.11 protein_coding missense_variant MODERATE 242C>T Ser81Leu
M0048432 DCLCOPFL_00017 16830 4 Skin 0.15 protein_coding missense_variant MODERATE 464A>G Gln155Arg
M0048433 DCLCOPFL_00017 16831 4 Skin 0.15 protein_coding synonymous_variant LOW 465A>G Gln155Gln
M0048434 DCLCOPFL_00017 16834 4 Skin 0.15 protein_coding missense_variant MODERATE 468T>G Asp156Glu
M0048435 DCLCOPFL_00017 16862 3 Skin 0.11 protein_coding missense_variant MODERATE 496G>A Val166Met
M0048436 DCLCOPFL_00017 16912 3 Skin 0.11 protein_coding missense_variant MODERATE 546C>G Phe182Leu
M0048437 DCLCOPFL_00017 16917 7 Skin 0.26 protein_coding missense_variant MODERATE 551C>T Ala184Val
M0048438 DCLCOPFL_00018 17303 7 Skin 0.26 protein_coding missense_variant MODERATE 362A>G Glu121Gly
M0048439 DCLCOPFL_00018 17467 6 Skin 0.22 protein_coding missense_variant MODERATE 526C>A Leu176Met
M0048440 DCLCOPFL_00018 17667 8 Skin 0.30 protein_coding missense_variant MODERATE 726T>G His242Gln
M0048441 DCLCOPFL_00018 17737 8 Skin 0.30 protein_coding synonymous_variant LOW 796C>A Arg266Arg
M0048442 DCLCOPFL_00018 17919 7 Skin 0.26 protein_coding synonymous_variant LOW 978T>C Asp326Asp
M0048443 DCLCOPFL_00018 18156 3 Skin 0.11 protein_coding synonymous_variant LOW 1215C>T Ala405Ala
M0048444 DCLCOPFL_00018 18578 8 Skin 0.30 protein_coding missense_variant MODERATE 1637G>A Gly546Asp
M0048445 DCLCOPFL_00018 18587 6 Skin 0.22 protein_coding missense_variant MODERATE 1646C>G Ala549Gly
M0048446 DCLCOPFL_00018 18617 6 Skin 0.22 protein_coding missense_variant MODERATE 1676G>A Arg559Lys
M0048447 DCLCOPFL_00018 18892 4 Skin 0.15 protein_coding missense_variant MODERATE 1951G>A Asp651Asn
M0048448 DCLCOPFL_00018 18912 4 Skin 0.15 protein_coding synonymous_variant LOW 1971A>T Arg657Arg
M0048449 DCLCOPFL_00018 18969 3 Skin 0.11 protein_coding synonymous_variant LOW 2028G>C Leu676Leu
M0048450 DCLCOPFL_00019 19631 6 Skin 0.22 protein_coding synonymous_variant LOW 417T>C Leu139Leu
M0048451 DCLCOPFL_00019 19641 4 Skin 0.15 protein_coding missense_variant MODERATE 427T>C Trp143Arg
M0048452 DCLCOPFL_00020 19785 3 Skin 0.11 protein_coding synonymous_variant LOW 855C>T Ala285Ala
M0048453 DCLCOPFL_00020 19968 5 Skin 0.19 protein_coding synonymous_variant LOW 672G>C Arg224Arg
M0048454 DCLCOPFL_00020 20371 3 Skin 0.11 protein_coding missense_variant MODERATE 269C>A Ala90Asp
M0048455 DCLCOPFL_00016 20728 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4413C>T None
M0048456 DCLCOPFL_00011 11306 5 Skin 0.19 protein_coding synonymous_variant LOW 36C>G Thr12Thr
M0048457 DCLCOPFL_00012 11588 3 Skin 0.11 protein_coding synonymous_variant LOW 108G>A Lys36Lys
M0048458 DCLCOPFL_00014 13166 4 Skin 0.15 protein_coding synonymous_variant LOW 96T>A Gly32Gly
M0048459 DCLCOPFL_00014 13448 3 Skin 0.11 protein_coding missense_variant MODERATE 378G>C Glu126Asp
M0048460 DCLCOPFL_00014 13456 4 Skin 0.15 protein_coding missense_variant MODERATE 386T>C Ile129Thr
M0048461 DCLCOPFL_00014 13649 3 Skin 0.11 protein_coding synonymous_variant LOW 579C>G Leu193Leu
M0048462 DCLCOPFL_00014 13709 3 Skin 0.11 protein_coding synonymous_variant LOW 639G>A Gly213Gly
M0048463 DCLCOPFL_00009 13751 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4332A>G None
M0048464 DCLCOPFL_00009 13758 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4339G>C None
M0048465 DCLCOPFL_00015 14037 3 Skin 0.11 protein_coding synonymous_variant LOW 165G>C Thr55Thr
M0048466 DCLCOPFL_00015 14751 6 Skin 0.22 protein_coding synonymous_variant LOW 879G>A Glu293Glu
M0048467 DCLCOPFL_00017 16541 4 Skin 0.15 protein_coding missense_variant MODERATE 175A>G Lys59Glu
M0048468 DCLCOPFL_00018 17161 3 Skin 0.11 protein_coding missense_variant MODERATE 220A>G Ser74Gly
M0048469 DCLCOPFL_00018 17615 6 Skin 0.22 protein_coding missense_variant MODERATE 674C>G Thr225Ser
M0048470 DCLCOPFL_00018 17616 6 Skin 0.22 protein_coding synonymous_variant LOW 675C>T Thr225Thr
M0048471 DCLCOPFL_00020 20100 4 Skin 0.15 protein_coding synonymous_variant LOW 540C>T Gly180Gly
M0048472 DCLCOPFL_00007 6827 3 Skin 0.11 protein_coding synonymous_variant LOW 427T>C Leu143Leu
M0048473 DCLCOPFL_00010 9721 4 Skin 0.15 protein_coding synonymous_variant LOW 234C>T Val78Val
M0048474 DCLCOPFL_00005 9958 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4727C>T None
M0048475 DCLCOPFL_00005 10060 5 Skin 0.19 protein_coding upstream_gene_variant MODIFIER -4829G>T None
M0048476 DCLCOPFL_00005 10144 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4913C>G None
M0048477 DCLCOPFL_00013 12681 3 Skin 0.11 protein_coding synonymous_variant LOW 291T>C Ala97Ala
M0048478 DCLCOPFL_00006 5392 3 Skin 0.11 protein_coding missense_variant MODERATE 142G>A Glu48Lys
M0048479 DCLCOPFL_00012 11540 3 Skin 0.11 protein_coding synonymous_variant LOW 60G>A Ala20Ala
M0048480 DCLCOPFL_00013 12777 3 Skin 0.11 protein_coding synonymous_variant LOW 195G>A Glu65Glu
M0048481 DCLCOPFL_00016 15794 4 Skin 0.15 protein_coding synonymous_variant LOW 522A>G Ala174Ala
M0048482 DCLCOPFL_00017 16535 3 Skin 0.11 protein_coding missense_variant MODERATE 169G>A Ala57Thr
M0048483 DCLCOPFL_00018 17700 4 Skin 0.15 protein_coding synonymous_variant LOW 759G>A Val253Val
M0048484 DCLCOPFL_00022 21147 3 Skin 0.11 protein_coding synonymous_variant LOW 324G>C Leu108Leu
M0048485 DCLCOPFL_00022 21165 3 Skin 0.11 protein_coding synonymous_variant LOW 306T>C Val102Val
M0048486 DCLCOPFL_00022 21297 3 Skin 0.11 protein_coding synonymous_variant LOW 174A>C Pro58Pro
M0048487 DCLCOPFL_00022 21375 3 Skin 0.11 protein_coding synonymous_variant LOW 96G>C Ala32Ala
M0048488 DCLCOPFL_00011 11313 3 Skin 0.11 protein_coding missense_variant MODERATE 29G>A Arg10Lys
M0048489 DCLCOPFL_00015 14031 3 Skin 0.11 protein_coding synonymous_variant LOW 159T>C Ile53Ile
M0048490 DCLCOPFL_00005 10034 3 Skin 0.11 protein_coding upstream_gene_variant MODIFIER -4803T>G None
M0048491 DCLCOPFL_00016 15842 3 Skin 0.11 protein_coding synonymous_variant LOW 474G>C Gly158Gly






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term