Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2591
  Reference Plasmid   1111525849854152_bin.51__k141_145415
  Reference Plasmid Size   7701
  Reference Plasmid GC Content   0.65
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048492 AMGCBCDH_00001 81 3 Skin 0.75 protein_coding synonymous_variant LOW 72T>C Cys24Cys
M0048493 AMGCBCDH_00002 248 3 Skin 0.75 protein_coding upstream_gene_variant MODIFIER -251C>T None
M0048494 AMGCBCDH_00002 819 3 Skin 0.75 protein_coding synonymous_variant LOW 321G>C Ala107Ala
M0048495 AMGCBCDH_00003 1895 3 Skin 0.75 protein_coding synonymous_variant LOW 144C>T Gly48Gly
M0048496 AMGCBCDH_00003 2588 3 Skin 0.75 protein_coding synonymous_variant LOW 837C>G Leu279Leu
M0048497 AMGCBCDH_00003 2597 3 Skin 0.75 protein_coding synonymous_variant LOW 846C>G Gly282Gly
M0048498 AMGCBCDH_00004 3366 3 Skin 0.75 protein_coding synonymous_variant LOW 504C>T Ala168Ala
M0048499 AMGCBCDH_00004 3552 3 Skin 0.75 protein_coding synonymous_variant LOW 690T>C Ala230Ala
M0048500 AMGCBCDH_00005 4000 3 Skin 0.75 protein_coding missense_variant MODERATE 218G>A Arg73Gln
M0048501 AMGCBCDH_00005 4002 3 Skin 0.75 protein_coding missense_variant MODERATE 220G>C Ala74Pro
M0048502 AMGCBCDH_00005 4003 3 Skin 0.75 protein_coding missense_variant MODERATE 221C>A Ala74Glu
M0048503 AMGCBCDH_00006 4957 3 Skin 0.75 protein_coding synonymous_variant LOW 393T>C Asn131Asn
M0048504 AMGCBCDH_00002 5296 3 Skin 0.75 protein_coding downstream_gene_variant MODIFIER *3634A>T None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term