Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2593
  Reference Plasmid   1111525849854152_bin.51__k141_255840
  Reference Plasmid Size   14116
  Reference Plasmid GC Content   0.62
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048510 BJBHCPID_00001 245 5 Skin 0.63 protein_coding downstream_gene_variant MODIFIER *109G>A None
M0048511 BJBHCPID_00001 315 5 Skin 0.63 protein_coding downstream_gene_variant MODIFIER *39A>G None
M0048512 BJBHCPID_00001 318 5 Skin 0.63 protein_coding downstream_gene_variant MODIFIER *36T>C None
M0048513 BJBHCPID_00001 350 5 Skin 0.63 protein_coding downstream_gene_variant MODIFIER *4C>A None
M0048514 BJBHCPID_00001 464 5 Skin 0.63 protein_coding missense_variant MODERATE 820A>C Ile274Leu
M0048515 BJBHCPID_00001 586 5 Skin 0.63 protein_coding missense_variant MODERATE 698T>A Val233Asp
M0048516 BJBHCPID_00001 825 4 Skin 0.50 protein_coding synonymous_variant LOW 459A>G Thr153Thr
M0048517 BJBHCPID_00001 921 5 Skin 0.63 protein_coding synonymous_variant LOW 363C>T Ile121Ile
M0048518 BJBHCPID_00001 1116 5 Skin 0.63 protein_coding synonymous_variant LOW 168T>C Phe56Phe
M0048519 BJBHCPID_00001 1218 5 Skin 0.63 protein_coding synonymous_variant LOW 66C>T Asp22Asp
M0048520 BJBHCPID_00001 1307 4 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -24C>T None
M0048521 BJBHCPID_00001 1380 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -97A>G None
M0048522 BJBHCPID_00002 1713 4 Skin 0.50 protein_coding synonymous_variant LOW 567T>C Asn189Asn
M0048523 BJBHCPID_00002 1857 5 Skin 0.63 protein_coding synonymous_variant LOW 423A>G Val141Val
M0048524 BJBHCPID_00002 1944 5 Skin 0.63 protein_coding synonymous_variant LOW 336T>C Gly112Gly
M0048525 BJBHCPID_00002 2018 4 Skin 0.50 protein_coding missense_variant MODERATE 262G>A Val88Met
M0048526 BJBHCPID_00002 2180 4 Skin 0.50 protein_coding synonymous_variant LOW 100C>T Leu34Leu
M0048527 BJBHCPID_00003 2811 5 Skin 0.63 protein_coding synonymous_variant LOW 432T>C Thr144Thr
M0048528 BJBHCPID_00004 3713 4 Skin 0.50 protein_coding synonymous_variant LOW 1149T>C Asp383Asp
M0048529 BJBHCPID_00004 3731 4 Skin 0.50 protein_coding missense_variant MODERATE 1131A>G Ile377Met
M0048530 BJBHCPID_00004 3740 4 Skin 0.50 protein_coding synonymous_variant LOW 1122C>T Gly374Gly
M0048531 BJBHCPID_00004 3786 4 Skin 0.50 protein_coding missense_variant MODERATE 1076C>G Ser359Cys
M0048532 BJBHCPID_00004 3787 4 Skin 0.50 protein_coding missense_variant MODERATE 1075T>A Ser359Thr
M0048533 BJBHCPID_00004 3788 4 Skin 0.50 protein_coding synonymous_variant LOW 1074T>G Leu358Leu
M0048534 BJBHCPID_00004 3791 4 Skin 0.50 protein_coding synonymous_variant LOW 1071G>A Gln357Gln
M0048535 BJBHCPID_00004 3794 4 Skin 0.50 protein_coding synonymous_variant LOW 1068C>T Asp356Asp
M0048536 BJBHCPID_00004 3797 4 Skin 0.50 protein_coding synonymous_variant LOW 1065T>C Gly355Gly
M0048537 BJBHCPID_00004 4010 5 Skin 0.63 protein_coding synonymous_variant LOW 852C>T Arg284Arg
M0048538 BJBHCPID_00004 4013 5 Skin 0.63 protein_coding synonymous_variant LOW 849C>T Val283Val
M0048539 BJBHCPID_00004 4016 5 Skin 0.63 protein_coding synonymous_variant LOW 846C>T Asp282Asp
M0048540 BJBHCPID_00004 4025 5 Skin 0.63 protein_coding synonymous_variant LOW 837C>T Arg279Arg
M0048541 BJBHCPID_00004 4037 5 Skin 0.63 protein_coding synonymous_variant LOW 825T>C Asn275Asn
M0048542 BJBHCPID_00004 4046 5 Skin 0.63 protein_coding synonymous_variant LOW 816A>C Gly272Gly
M0048543 BJBHCPID_00004 4049 5 Skin 0.63 protein_coding missense_variant MODERATE 813C>G Ile271Met
M0048544 BJBHCPID_00004 4051 5 Skin 0.63 protein_coding missense_variant MODERATE 811A>C Ile271Leu
M0048545 BJBHCPID_00004 4067 5 Skin 0.63 protein_coding synonymous_variant LOW 795A>G Ser265Ser
M0048546 BJBHCPID_00004 4078 5 Skin 0.63 protein_coding missense_variant MODERATE 784G>T Ala262Ser
M0048547 BJBHCPID_00004 4097 5 Skin 0.63 protein_coding synonymous_variant LOW 765T>C Asn255Asn
M0048548 BJBHCPID_00004 4106 5 Skin 0.63 protein_coding synonymous_variant LOW 756C>G Thr252Thr
M0048549 BJBHCPID_00004 4124 5 Skin 0.63 protein_coding synonymous_variant LOW 738C>G Thr246Thr
M0048550 BJBHCPID_00004 4148 5 Skin 0.63 protein_coding synonymous_variant LOW 714G>T Gly238Gly
M0048551 BJBHCPID_00004 4159 5 Skin 0.63 protein_coding synonymous_variant LOW 703T>C Leu235Leu
M0048552 BJBHCPID_00004 4193 5 Skin 0.63 protein_coding synonymous_variant LOW 669T>C Arg223Arg
M0048553 BJBHCPID_00005 4896 5 Skin 0.63 protein_coding synonymous_variant LOW 732A>G Pro244Pro
M0048554 BJBHCPID_00001 5648 5 Skin 0.63 protein_coding upstream_gene_variant MODIFIER -4365A>C None
M0048555 BJBHCPID_00006 5786 5 Skin 0.63 protein_coding missense_variant MODERATE 918G>T Gln306His
M0048556 BJBHCPID_00006 5800 5 Skin 0.63 protein_coding missense_variant MODERATE 904G>A Gly302Arg
M0048557 BJBHCPID_00006 6334 5 Skin 0.63 protein_coding missense_variant MODERATE 370G>A Ala124Thr
M0048558 BJBHCPID_00006 6374 5 Skin 0.63 protein_coding synonymous_variant LOW 330T>C Gly110Gly
M0048559 BJBHCPID_00006 6488 5 Skin 0.63 protein_coding synonymous_variant LOW 216T>C His72His
M0048560 BJBHCPID_00007 6994 4 Skin 0.50 protein_coding synonymous_variant LOW 654C>T Val218Val
M0048561 BJBHCPID_00007 7097 4 Skin 0.50 protein_coding missense_variant MODERATE 551G>A Gly184Asp
M0048562 BJBHCPID_00004 4418 4 Skin 0.50 protein_coding synonymous_variant LOW 444G>A Pro148Pro
M0048563 BJBHCPID_00005 5562 3 Skin 0.38 protein_coding synonymous_variant LOW 66C>T His22His






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term