Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2594
  Reference Plasmid   1111525849854152_bin.51__k141_274519
  Reference Plasmid Size   7134
  Reference Plasmid GC Content   0.61
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048564 JHEJMODE_00005 167 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4803A>G None
M0048565 JHEJMODE_00005 235 3 Skin 0.60 protein_coding upstream_gene_variant MODIFIER -4735C>A None
M0048566 JHEJMODE_00001 464 3 Skin 0.60 protein_coding synonymous_variant LOW 741A>G Gln247Gln
M0048567 JHEJMODE_00001 467 3 Skin 0.60 protein_coding synonymous_variant LOW 738G>C Leu246Leu
M0048568 JHEJMODE_00001 470 3 Skin 0.60 protein_coding synonymous_variant LOW 735G>C Thr245Thr
M0048569 JHEJMODE_00001 482 3 Skin 0.60 protein_coding synonymous_variant LOW 723G>C Leu241Leu
M0048570 JHEJMODE_00001 507 3 Skin 0.60 protein_coding missense_variant MODERATE 698C>G Ser233Cys
M0048571 JHEJMODE_00001 508 3 Skin 0.60 protein_coding missense_variant MODERATE 697T>A Ser233Thr
M0048572 JHEJMODE_00001 632 3 Skin 0.60 protein_coding synonymous_variant LOW 573A>C Ala191Ala
M0048573 JHEJMODE_00001 844 3 Skin 0.60 protein_coding synonymous_variant LOW 361T>C Leu121Leu
M0048574 JHEJMODE_00001 845 3 Skin 0.60 protein_coding synonymous_variant LOW 360T>C Phe120Phe
M0048575 JHEJMODE_00001 1010 3 Skin 0.60 protein_coding synonymous_variant LOW 195C>A Gly65Gly
M0048576 JHEJMODE_00001 1028 3 Skin 0.60 protein_coding synonymous_variant LOW 177C>G Pro59Pro
M0048577 JHEJMODE_00001 1031 3 Skin 0.60 protein_coding synonymous_variant LOW 174C>G Leu58Leu
M0048578 JHEJMODE_00001 1033 3 Skin 0.60 protein_coding missense_variant MODERATE 172C>T Leu58Phe
M0048579 JHEJMODE_00001 1037 3 Skin 0.60 protein_coding synonymous_variant LOW 168C>T Phe56Phe
M0048580 JHEJMODE_00001 1064 3 Skin 0.60 protein_coding synonymous_variant LOW 141C>T Phe47Phe






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term