Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2615
  Reference Plasmid   1111525849857862_bin.26__k141_90724
  Reference Plasmid Size   3617
  Reference Plasmid GC Content   0.53
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048948 GLGBHHAL_00003 1489 8 Skin 0.62 protein_coding upstream_gene_variant MODIFIER -141C>T None
M0048949 GLGBHHAL_00003 1515 9 Skin 0.69 protein_coding upstream_gene_variant MODIFIER -115A>G None
M0048950 GLGBHHAL_00003 1520 9 Skin 0.69 protein_coding upstream_gene_variant MODIFIER -110G>A None
M0048951 GLGBHHAL_00003 1524 9 Skin 0.69 protein_coding upstream_gene_variant MODIFIER -106T>C None
M0048952 GLGBHHAL_00004 2427 3 Skin 0.23 protein_coding synonymous_variant LOW 243G>A Lys81Lys
M0048953 GLGBHHAL_00004 2454 5 Skin 0.38 protein_coding synonymous_variant LOW 270A>G Gly90Gly
M0048954 GLGBHHAL_00004 2481 3 Skin 0.23 protein_coding synonymous_variant LOW 297C>T Ile99Ile
M0048955 GLGBHHAL_00004 2487 3 Skin 0.23 protein_coding synonymous_variant LOW 303G>A Pro101Pro
M0048956 GLGBHHAL_00004 2505 3 Skin 0.23 protein_coding synonymous_variant LOW 321C>A Arg107Arg
M0048957 GLGBHHAL_00004 2511 3 Skin 0.23 protein_coding synonymous_variant LOW 327T>C Asn109Asn
M0048958 GLGBHHAL_00004 2520 3 Skin 0.23 protein_coding synonymous_variant LOW 336A>C Ala112Ala
M0048959 GLGBHHAL_00004 2523 3 Skin 0.23 protein_coding synonymous_variant LOW 339T>G Ala113Ala
M0048960 GLGBHHAL_00004 2706 5 Skin 0.38 protein_coding synonymous_variant LOW 522T>C Arg174Arg
M0048961 GLGBHHAL_00004 2574 3 Skin 0.23 protein_coding synonymous_variant LOW 390G>A Gln130Gln
M0048962 GLGBHHAL_00004 2580 3 Skin 0.23 protein_coding synonymous_variant LOW 396C>T His132His
M0048963 GLGBHHAL_00004 2592 3 Skin 0.23 protein_coding synonymous_variant LOW 408A>T Arg136Arg
M0048964 GLGBHHAL_00004 2610 3 Skin 0.23 protein_coding synonymous_variant LOW 426C>T Gly142Gly
M0048965 GLGBHHAL_00004 2616 3 Skin 0.23 protein_coding synonymous_variant LOW 432T>C Leu144Leu
M0048966 GLGBHHAL_00004 2622 3 Skin 0.23 protein_coding synonymous_variant LOW 438T>C Tyr146Tyr
M0048967 GLGBHHAL_00004 2649 3 Skin 0.23 protein_coding synonymous_variant LOW 465C>T Val155Val
M0048968 GLGBHHAL_00004 2653 3 Skin 0.23 protein_coding synonymous_variant LOW 469C>T Leu157Leu
M0048969 GLGBHHAL_00002 1332 4 Skin 0.31 protein_coding synonymous_variant LOW 594G>A Thr198Thr






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term
GLGBHHAL_00004 8.A.5.1.5 75.1 2.5e-152 1 346 1.0000 1.0000 8 Accessory Factors Involved in Transport 8.A Auxiliary transport proteins 8.A.5 The Voltage-gated K+ Channel β-subunit (Kvβ) Family