Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2616
  Reference Plasmid   1111525849857862_bin.26__k141_92731
  Reference Plasmid Size   8328
  Reference Plasmid GC Content   0.55
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0048970 DKKHDCIJ_00001 2233 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -69A>G None
M0048971 DKKHDCIJ_00002 2825 3 Skin 0.18 protein_coding missense_variant MODERATE 548C>T Ala183Val
M0048972 DKKHDCIJ_00002 2976 4 Skin 0.24 protein_coding synonymous_variant LOW 699A>G Pro233Pro
M0048973 DKKHDCIJ_00004 4230 3 Skin 0.18 protein_coding missense_variant MODERATE 164T>G Leu55Arg
M0048974 DKKHDCIJ_00004 4267 3 Skin 0.18 protein_coding synonymous_variant LOW 201T>C Thr67Thr
M0048975 DKKHDCIJ_00004 4672 6 Skin 0.35 protein_coding synonymous_variant LOW 606G>A Ala202Ala
M0048976 DKKHDCIJ_00005 4836 4 Skin 0.24 protein_coding synonymous_variant LOW 81A>G Pro27Pro
M0048977 DKKHDCIJ_00005 5094 4 Skin 0.24 protein_coding synonymous_variant LOW 339T>C Asp113Asp
M0048978 DKKHDCIJ_00006 5374 5 Skin 0.29 protein_coding synonymous_variant LOW 705T>C Ala235Ala
M0048979 DKKHDCIJ_00006 6054 4 Skin 0.24 protein_coding missense_variant MODERATE 25A>G Met9Val
M0048980 DKKHDCIJ_00010 7349 6 Skin 0.35 protein_coding synonymous_variant LOW 129C>A Ala43Ala
M0048981 DKKHDCIJ_00010 7409 7 Skin 0.41 protein_coding synonymous_variant LOW 69T>C Asn23Asn
M0048982 DKKHDCIJ_00010 7214 6 Skin 0.35 protein_coding missense_variant MODERATE 264G>T Gln88His
M0048983 DKKHDCIJ_00006 7495 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -1417A>C None
M0048984 DKKHDCIJ_00007 6416 4 Skin 0.24 protein_coding synonymous_variant LOW 195T>G Gly65Gly
M0048985 DKKHDCIJ_00007 6515 4 Skin 0.24 protein_coding synonymous_variant LOW 294G>A Ala98Ala
M0048986 DKKHDCIJ_00007 6518 4 Skin 0.24 protein_coding synonymous_variant LOW 297G>A Leu99Leu
M0048987 DKKHDCIJ_00006 7596 8 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -1518T>G None
M0048988 DKKHDCIJ_00006 7604 8 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -1526A>G None
M0048989 DKKHDCIJ_00006 7605 8 Skin 0.47 protein_coding upstream_gene_variant MODIFIER -1527C>T None
M0048990 DKKHDCIJ_00006 5668 3 Skin 0.18 protein_coding synonymous_variant LOW 411C>T Gly137Gly
M0048991 DKKHDCIJ_00008 6633 5 Skin 0.29 protein_coding missense_variant MODERATE 38A>C Lys13Thr
M0048992 DKKHDCIJ_00008 6663 4 Skin 0.24 protein_coding missense_variant MODERATE 68A>G Asn23Ser
M0048993 DKKHDCIJ_00008 6672 5 Skin 0.29 protein_coding missense_variant MODERATE 77T>C Phe26Ser
M0048994 DKKHDCIJ_00008 6675 5 Skin 0.29 protein_coding missense_variant MODERATE 80C>A Thr27Lys
M0048995 DKKHDCIJ_00008 6693 4 Skin 0.24 protein_coding missense_variant MODERATE 98A>G Tyr33Cys
M0048996 DKKHDCIJ_00001 6733 4 Skin 0.24 protein_coding upstream_gene_variant MODIFIER -4569C>T None
M0048997 DKKHDCIJ_00002 2343 3 Skin 0.18 protein_coding synonymous_variant LOW 66T>A Val22Val
M0048998 DKKHDCIJ_00002 2454 3 Skin 0.18 protein_coding synonymous_variant LOW 177G>T Gly59Gly
M0048999 DKKHDCIJ_00003 3882 3 Skin 0.18 protein_coding synonymous_variant LOW 291G>A Leu97Leu
M0049000 DKKHDCIJ_00006 7650 6 Skin 0.35 protein_coding upstream_gene_variant MODIFIER -1572C>T None
M0049001 DKKHDCIJ_00007 6564 3 Skin 0.18 protein_coding missense_variant MODERATE 343A>G Ile115Val
M0049002 DKKHDCIJ_00002 1157 3 Skin 0.18 protein_coding upstream_gene_variant MODIFIER -1121G>T None
M0049003 DKKHDCIJ_00001 2129 3 Skin 0.18 protein_coding synonymous_variant LOW 36T>C Leu12Leu






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term