Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2627
  Reference Plasmid   1111525849858550_bin.3__k141_358765
  Reference Plasmid Size   7898
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0049733 IHIIPJJE_00004 2428 3 Skin 0.60 protein_coding synonymous_variant LOW 910C>T Leu304Leu
M0049734 IHIIPJJE_00002 3527 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -2387A>C None
M0049735 IHIIPJJE_00005 3753 4 Skin 0.80 protein_coding synonymous_variant LOW 528A>G Ser176Ser
M0049736 IHIIPJJE_00005 3761 4 Skin 0.80 protein_coding synonymous_variant LOW 520T>C Leu174Leu
M0049737 IHIIPJJE_00005 3762 4 Skin 0.80 protein_coding synonymous_variant LOW 519T>C Ser173Ser
M0049738 IHIIPJJE_00005 3962 3 Skin 0.60 protein_coding synonymous_variant LOW 319T>C Leu107Leu
M0049739 IHIIPJJE_00002 4283 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -3143G>C None
M0049740 IHIIPJJE_00006 4801 4 Skin 0.80 protein_coding missense_variant MODERATE 37C>A Leu13Ile
M0049741 IHIIPJJE_00002 4860 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -3720C>T None
M0049742 IHIIPJJE_00002 4877 4 Skin 0.80 protein_coding upstream_gene_variant MODIFIER -3737A>G None
M0049743 IHIIPJJE_00007 5260 3 Skin 0.60 protein_coding synonymous_variant LOW 258C>T Gly86Gly
M0049744 IHIIPJJE_00007 5681 3 Skin 0.60 protein_coding synonymous_variant LOW 679T>C Leu227Leu
M0049745 IHIIPJJE_00008 7181 3 Skin 0.60 protein_coding synonymous_variant LOW 903A>T Gly301Gly
M0049746 IHIIPJJE_00007 5110 3 Skin 0.60 protein_coding synonymous_variant LOW 108G>A Glu36Glu
M0049747 IHIIPJJE_00007 5161 3 Skin 0.60 protein_coding synonymous_variant LOW 159A>C Ala53Ala
M0049748 IHIIPJJE_00007 5521 3 Skin 0.60 protein_coding synonymous_variant LOW 519T>C Gly173Gly
M0049749 IHIIPJJE_00007 5872 3 Skin 0.60 protein_coding synonymous_variant LOW 870G>C Gly290Gly
M0049750 IHIIPJJE_00008 6820 3 Skin 0.60 protein_coding missense_variant MODERATE 542T>C Val181Ala






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term