Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2641
  Reference Plasmid   1111525849858868_bin.24__k141_267935
  Reference Plasmid Size   6063
  Reference Plasmid GC Content   0.70
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0050311 ICHDLFGL_00001 646 3 Skin 0.43 protein_coding missense_variant MODERATE 643A>G Thr215Ala
M0050312 ICHDLFGL_00002 1167 3 Skin 0.43 protein_coding synonymous_variant LOW 2001A>G Glu667Glu
M0050313 ICHDLFGL_00002 1317 3 Skin 0.43 protein_coding synonymous_variant LOW 1851C>G Ser617Ser
M0050314 ICHDLFGL_00002 1401 4 Skin 0.57 protein_coding synonymous_variant LOW 1767T>C Thr589Thr
M0050315 ICHDLFGL_00002 1564 4 Skin 0.57 protein_coding missense_variant MODERATE 1604C>T Ala535Val
M0050316 ICHDLFGL_00002 1578 3 Skin 0.43 protein_coding synonymous_variant LOW 1590C>T Leu530Leu
M0050317 ICHDLFGL_00002 1719 3 Skin 0.43 protein_coding synonymous_variant LOW 1449G>C Ala483Ala
M0050318 ICHDLFGL_00002 1734 3 Skin 0.43 protein_coding synonymous_variant LOW 1434T>C Gly478Gly
M0050319 ICHDLFGL_00002 1770 3 Skin 0.43 protein_coding synonymous_variant LOW 1398G>C Gly466Gly
M0050320 ICHDLFGL_00002 2016 3 Skin 0.43 protein_coding synonymous_variant LOW 1152T>C Gly384Gly
M0050321 ICHDLFGL_00002 2058 4 Skin 0.57 protein_coding synonymous_variant LOW 1110C>G Pro370Pro
M0050322 ICHDLFGL_00002 2118 4 Skin 0.57 protein_coding synonymous_variant LOW 1050G>C Ala350Ala
M0050323 ICHDLFGL_00002 2181 4 Skin 0.57 protein_coding synonymous_variant LOW 987C>G Pro329Pro
M0050324 ICHDLFGL_00002 2184 3 Skin 0.43 protein_coding synonymous_variant LOW 984A>G Glu328Glu
M0050325 ICHDLFGL_00002 2199 3 Skin 0.43 protein_coding synonymous_variant LOW 969C>G Gly323Gly
M0050326 ICHDLFGL_00002 2254 3 Skin 0.43 protein_coding missense_variant MODERATE 914C>A Pro305Gln
M0050327 ICHDLFGL_00002 2262 3 Skin 0.43 protein_coding synonymous_variant LOW 906G>C Ala302Ala
M0050328 ICHDLFGL_00002 2298 3 Skin 0.43 protein_coding synonymous_variant LOW 870T>C His290His
M0050329 ICHDLFGL_00002 2301 3 Skin 0.43 protein_coding synonymous_variant LOW 867C>G Thr289Thr
M0050330 ICHDLFGL_00002 2364 3 Skin 0.43 protein_coding synonymous_variant LOW 804C>G Ala268Ala
M0050331 ICHDLFGL_00002 2607 3 Skin 0.43 protein_coding synonymous_variant LOW 561C>T Asp187Asp
M0050332 ICHDLFGL_00002 2613 3 Skin 0.43 protein_coding synonymous_variant LOW 555C>G Thr185Thr
M0050333 ICHDLFGL_00002 2689 3 Skin 0.43 protein_coding missense_variant MODERATE 479G>A Arg160Lys
M0050334 ICHDLFGL_00002 3003 3 Skin 0.43 protein_coding synonymous_variant LOW 165T>C His55His
M0050335 ICHDLFGL_00002 3081 3 Skin 0.43 protein_coding synonymous_variant LOW 87C>G Gly29Gly
M0050336 ICHDLFGL_00002 3105 3 Skin 0.43 protein_coding synonymous_variant LOW 63T>C Asn21Asn
M0050337 ICHDLFGL_00003 3449 3 Skin 0.43 protein_coding synonymous_variant LOW 690C>T Tyr230Tyr
M0050338 ICHDLFGL_00003 3464 3 Skin 0.43 protein_coding synonymous_variant LOW 675C>G Arg225Arg
M0050339 ICHDLFGL_00003 4094 3 Skin 0.43 protein_coding synonymous_variant LOW 45T>G Ala15Ala
M0050340 ICHDLFGL_00003 4101 3 Skin 0.43 protein_coding missense_variant MODERATE 38A>C Asp13Ala
M0050341 ICHDLFGL_00002 2043 3 Skin 0.43 protein_coding synonymous_variant LOW 1125C>G Ala375Ala
M0050342 ICHDLFGL_00002 2468 3 Skin 0.43 protein_coding missense_variant MODERATE 700G>C Val234Leu
M0050343 ICHDLFGL_00004 4299 3 Skin 0.43 protein_coding missense_variant MODERATE 343A>G Lys115Glu
M0050344 ICHDLFGL_00004 4630 3 Skin 0.43 protein_coding synonymous_variant LOW 12A>C Thr4Thr
M0050345 ICHDLFGL_00002 4675 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1508C>T None
M0050346 ICHDLFGL_00002 4678 3 Skin 0.43 protein_coding upstream_gene_variant MODIFIER -1511A>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term