Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2646
  Reference Plasmid   1111525849858868_bin.34__k141_100074
  Reference Plasmid Size   4320
  Reference Plasmid GC Content   0.64
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051057 CJMNDFLK_00001 42 4 Skin 0.57 protein_coding synonymous_variant LOW 27T>C Arg9Arg
M0051058 CJMNDFLK_00001 93 3 Skin 0.43 protein_coding synonymous_variant LOW 78T>C Phe26Phe
M0051059 CJMNDFLK_00001 95 3 Skin 0.43 protein_coding missense_variant MODERATE 80A>G Gln27Arg
M0051060 CJMNDFLK_00002 551 4 Skin 0.57 protein_coding synonymous_variant LOW 267A>G Thr89Thr
M0051061 CJMNDFLK_00002 931 3 Skin 0.43 protein_coding missense_variant MODERATE 647T>C Val216Ala
M0051062 CJMNDFLK_00003 969 3 Skin 0.43 protein_coding missense_variant MODERATE 452A>G Glu151Gly
M0051063 CJMNDFLK_00003 1262 3 Skin 0.43 protein_coding synonymous_variant LOW 159T>C Ala53Ala
M0051064 CJMNDFLK_00003 1269 3 Skin 0.43 protein_coding missense_variant MODERATE 152G>C Ser51Thr
M0051065 CJMNDFLK_00004 1477 3 Skin 0.43 protein_coding stop_lost&splice_region_variant HIGH 196T>C Ter66Glnext*?
M0051066 CJMNDFLK_00005 2458 3 Skin 0.43 protein_coding synonymous_variant LOW 343C>T Leu115Leu
M0051067 CJMNDFLK_00006 3152 3 Skin 0.43 protein_coding missense_variant MODERATE 476A>G Lys159Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
CJMNDFLK_00007 UQN07423.1|CE14 82.9 3.54e-138 1 228 1 0.9421





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term