Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2647
  Reference Plasmid   1111525849858868_bin.34__k141_149501
  Reference Plasmid Size   16284
  Reference Plasmid GC Content   0.68
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051068 MKGNPFOK_00002 2467 4 Skin 0.40 protein_coding synonymous_variant LOW 915T>C Asn305Asn
M0051069 MKGNPFOK_00003 3039 3 Skin 0.30 protein_coding synonymous_variant LOW 444C>T Ala148Ala
M0051070 MKGNPFOK_00003 3153 3 Skin 0.30 protein_coding synonymous_variant LOW 558A>C Ala186Ala
M0051071 MKGNPFOK_00004 3432 4 Skin 0.40 protein_coding missense_variant MODERATE 451T>G Ser151Ala
M0051072 MKGNPFOK_00004 3433 4 Skin 0.40 protein_coding synonymous_variant LOW 450G>A Lys150Lys
M0051073 MKGNPFOK_00004 3283 3 Skin 0.30 protein_coding synonymous_variant LOW 600A>G Glu200Glu
M0051074 MKGNPFOK_00004 3496 3 Skin 0.30 protein_coding synonymous_variant LOW 387A>G Gly129Gly
M0051075 MKGNPFOK_00004 3521 3 Skin 0.30 protein_coding missense_variant MODERATE 362C>G Thr121Ser
M0051076 MKGNPFOK_00005 5196 3 Skin 0.30 protein_coding missense_variant MODERATE 1109G>C Trp370Ser
M0051077 MKGNPFOK_00004 7820 3 Skin 0.30 protein_coding upstream_gene_variant MODIFIER -3938C>G None
M0051078 MKGNPFOK_00009 8752 3 Skin 0.30 protein_coding synonymous_variant LOW 723C>T Ala241Ala
M0051079 MKGNPFOK_00009 9000 3 Skin 0.30 protein_coding missense_variant MODERATE 971A>G His324Arg
M0051080 MKGNPFOK_00006 5895 3 Skin 0.30 protein_coding missense_variant MODERATE 349A>T Ile117Phe
M0051081 MKGNPFOK_00012 10548 3 Skin 0.30 protein_coding missense_variant MODERATE 187A>G Asn63Asp
M0051082 MKGNPFOK_00017 14006 3 Skin 0.30 protein_coding missense_variant MODERATE 508C>T Arg170Trp






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term