Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2648
  Reference Plasmid   1111525849858868_bin.34__k141_297107
  Reference Plasmid Size   2121
  Reference Plasmid GC Content   0.63
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051083 NKKBINAD_00001 332 4 Skin 0.67 protein_coding synonymous_variant LOW 75G>A Glu25Glu
M0051084 NKKBINAD_00001 338 4 Skin 0.67 protein_coding synonymous_variant LOW 81C>G Leu27Leu
M0051085 NKKBINAD_00001 347 4 Skin 0.67 protein_coding synonymous_variant LOW 90C>T Asp30Asp
M0051086 NKKBINAD_00001 359 4 Skin 0.67 protein_coding synonymous_variant LOW 102C>T Asp34Asp
M0051087 NKKBINAD_00001 362 4 Skin 0.67 protein_coding synonymous_variant LOW 105T>C Thr35Thr
M0051088 NKKBINAD_00001 364 4 Skin 0.67 protein_coding missense_variant MODERATE 107A>G Gln36Arg
M0051089 NKKBINAD_00001 374 4 Skin 0.67 protein_coding synonymous_variant LOW 117C>G Leu39Leu
M0051090 NKKBINAD_00001 377 4 Skin 0.67 protein_coding synonymous_variant LOW 120C>T Asp40Asp
M0051091 NKKBINAD_00001 383 4 Skin 0.67 protein_coding synonymous_variant LOW 126T>C Ala42Ala
M0051092 NKKBINAD_00001 395 4 Skin 0.67 protein_coding synonymous_variant LOW 138G>A Lys46Lys
M0051093 NKKBINAD_00001 401 4 Skin 0.67 protein_coding missense_variant MODERATE 144C>G Asn48Lys
M0051094 NKKBINAD_00001 443 3 Skin 0.50 protein_coding synonymous_variant LOW 186G>C Leu62Leu
M0051095 NKKBINAD_00001 449 3 Skin 0.50 protein_coding synonymous_variant LOW 192T>C Gly64Gly
M0051096 NKKBINAD_00001 450 3 Skin 0.50 protein_coding missense_variant MODERATE 193A>G Ser65Gly
M0051097 NKKBINAD_00001 452 3 Skin 0.50 protein_coding synonymous_variant LOW 195C>T Ser65Ser
M0051098 NKKBINAD_00001 608 3 Skin 0.50 protein_coding synonymous_variant LOW 351C>G Thr117Thr
M0051099 NKKBINAD_00001 1161 5 Skin 0.83 protein_coding missense_variant MODERATE 904G>A Val302Met
M0051100 NKKBINAD_00001 1163 5 Skin 0.83 protein_coding synonymous_variant LOW 906G>C Val302Val
M0051101 NKKBINAD_00001 1165 5 Skin 0.83 protein_coding missense_variant MODERATE 908G>A Ser303Asn
M0051102 NKKBINAD_00002 1782 5 Skin 0.83 protein_coding missense_variant MODERATE 146T>C Met49Thr
M0051103 NKKBINAD_00001 1601 3 Skin 0.50 protein_coding synonymous_variant LOW 1344T>C Tyr448Tyr
M0051104 NKKBINAD_00001 896 3 Skin 0.50 protein_coding synonymous_variant LOW 639G>A Glu213Glu
M0051105 NKKBINAD_00001 1067 3 Skin 0.50 protein_coding synonymous_variant LOW 810G>C Pro270Pro
M0051106 NKKBINAD_00001 1070 3 Skin 0.50 protein_coding synonymous_variant LOW 813G>A Val271Val
M0051107 NKKBINAD_00001 1073 3 Skin 0.50 protein_coding synonymous_variant LOW 816G>C Ser272Ser






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term