Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2653
  Reference Plasmid   1111525849858958_bin.32__k141_1600
  Reference Plasmid Size   17922
  Reference Plasmid GC Content   0.60
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051179 EEDJCAEJ_00001 145 4 Skin 0.06 protein_coding synonymous_variant LOW 105T>C Ile35Ile
M0051180 EEDJCAEJ_00001 175 4 Skin 0.06 protein_coding synonymous_variant LOW 135T>C Val45Val
M0051181 EEDJCAEJ_00001 190 4 Skin 0.06 protein_coding synonymous_variant LOW 150C>G Ser50Ser
M0051182 EEDJCAEJ_00001 199 4 Skin 0.06 protein_coding synonymous_variant LOW 159T>C Asp53Asp
M0051183 EEDJCAEJ_00001 202 4 Skin 0.06 protein_coding synonymous_variant LOW 162C>G Ser54Ser
M0051184 EEDJCAEJ_00001 203 4 Skin 0.06 protein_coding synonymous_variant LOW 163C>T Leu55Leu
M0051185 EEDJCAEJ_00001 220 4 Skin 0.06 protein_coding synonymous_variant LOW 180G>A Glu60Glu
M0051186 EEDJCAEJ_00003 2772 14 Skin 0.22 protein_coding upstream_gene_variant MODIFIER -6A>G None
M0051187 EEDJCAEJ_00003 3461 55 Skin 0.86 protein_coding upstream_gene_variant MODIFIER -695G>A None
M0051188 EEDJCAEJ_00005 3624 3 Skin 0.05 protein_coding synonymous_variant LOW 264A>T Ala88Ala
M0051189 EEDJCAEJ_00006 4177 50 Skin 0.78 protein_coding missense_variant MODERATE 913A>G Ile305Val
M0051190 EEDJCAEJ_00003 6863 23 Skin 0.36 protein_coding upstream_gene_variant MODIFIER -4097C>T None
M0051191 EEDJCAEJ_00008 7262 56 Skin 0.88 protein_coding synonymous_variant LOW 1128A>G Thr376Thr
M0051192 EEDJCAEJ_00004 3197 12 Skin 0.19 protein_coding synonymous_variant LOW 153G>A Gly51Gly
M0051193 EEDJCAEJ_00004 3275 11 Skin 0.17 protein_coding synonymous_variant LOW 75T>C Asp25Asp
M0051194 EEDJCAEJ_00003 3411 5 Skin 0.08 protein_coding upstream_gene_variant MODIFIER -645G>A None
M0051195 EEDJCAEJ_00007 5964 12 Skin 0.19 protein_coding missense_variant MODERATE 575C>T Ala192Val
M0051196 EEDJCAEJ_00004 3172 3 Skin 0.05 protein_coding missense_variant MODERATE 178G>A Ala60Thr
M0051197 EEDJCAEJ_00009 9168 10 Skin 0.16 protein_coding missense_variant MODERATE 442C>G Leu148Val
M0051198 EEDJCAEJ_00006 4163 4 Skin 0.06 protein_coding synonymous_variant LOW 927T>C Ser309Ser
M0051199 EEDJCAEJ_00006 4379 6 Skin 0.09 protein_coding synonymous_variant LOW 711G>A Gly237Gly
M0051200 EEDJCAEJ_00006 4394 6 Skin 0.09 protein_coding synonymous_variant LOW 696T>C Ile232Ile
M0051201 EEDJCAEJ_00006 4397 6 Skin 0.09 protein_coding synonymous_variant LOW 693C>T Val231Val
M0051202 EEDJCAEJ_00006 4859 3 Skin 0.05 protein_coding synonymous_variant LOW 231T>C Asp77Asp
M0051203 EEDJCAEJ_00006 4866 3 Skin 0.05 protein_coding missense_variant MODERATE 224G>A Arg75His
M0051204 EEDJCAEJ_00006 4931 3 Skin 0.05 protein_coding synonymous_variant LOW 159C>T Leu53Leu
M0051205 EEDJCAEJ_00006 4943 3 Skin 0.05 protein_coding synonymous_variant LOW 147T>C Ser49Ser
M0051206 EEDJCAEJ_00006 4948 3 Skin 0.05 protein_coding synonymous_variant LOW 142C>T Leu48Leu
M0051207 EEDJCAEJ_00007 5938 3 Skin 0.05 protein_coding missense_variant MODERATE 601C>T Leu201Phe
M0051208 EEDJCAEJ_00007 5990 3 Skin 0.05 protein_coding synonymous_variant LOW 549G>A Ala183Ala
M0051209 EEDJCAEJ_00007 5995 3 Skin 0.05 protein_coding missense_variant MODERATE 544A>G Ile182Val
M0051210 EEDJCAEJ_00007 6518 3 Skin 0.05 protein_coding synonymous_variant LOW 21C>T Val7Val
M0051211 EEDJCAEJ_00007 6523 3 Skin 0.05 protein_coding missense_variant MODERATE 16T>C Ser6Pro
M0051212 EEDJCAEJ_00003 6550 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3784G>A None
M0051213 EEDJCAEJ_00003 6562 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3796T>C None
M0051214 EEDJCAEJ_00003 6588 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3822G>A None
M0051215 EEDJCAEJ_00003 6599 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3833G>A None
M0051216 EEDJCAEJ_00003 6636 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3870G>A None
M0051217 EEDJCAEJ_00003 6712 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3946G>A None
M0051218 EEDJCAEJ_00003 6719 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -3953A>C None
M0051219 EEDJCAEJ_00003 6783 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4017G>T None
M0051220 EEDJCAEJ_00003 6795 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4029C>T None
M0051221 EEDJCAEJ_00003 6852 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -4086T>C None
M0051222 EEDJCAEJ_00008 7115 4 Skin 0.06 protein_coding synonymous_variant LOW 1275C>A Arg425Arg
M0051223 EEDJCAEJ_00008 7118 6 Skin 0.09 protein_coding synonymous_variant LOW 1272C>T Ser424Ser
M0051224 EEDJCAEJ_00008 7387 3 Skin 0.05 protein_coding missense_variant MODERATE 1003A>G Thr335Ala
M0051225 EEDJCAEJ_00008 7388 3 Skin 0.05 protein_coding synonymous_variant LOW 1002G>A Gln334Gln
M0051226 EEDJCAEJ_00008 7409 3 Skin 0.05 protein_coding synonymous_variant LOW 981T>C Ala327Ala
M0051227 EEDJCAEJ_00005 3752 3 Skin 0.05 protein_coding missense_variant MODERATE 136C>T Pro46Ser
M0051228 EEDJCAEJ_00005 3791 3 Skin 0.05 protein_coding missense_variant MODERATE 97A>G Ile33Val
M0051229 EEDJCAEJ_00005 3825 4 Skin 0.06 protein_coding synonymous_variant LOW 63G>C Ala21Ala
M0051230 EEDJCAEJ_00005 3852 4 Skin 0.06 protein_coding synonymous_variant LOW 36T>C Thr12Thr
M0051231 EEDJCAEJ_00009 8996 8 Skin 0.13 protein_coding missense_variant MODERATE 614G>A Arg205His
M0051232 EEDJCAEJ_00014 12383 21 Skin 0.33 protein_coding missense_variant MODERATE 1796G>A Arg599His
M0051233 EEDJCAEJ_00015 14620 6 Skin 0.09 protein_coding missense_variant MODERATE 176C>G Pro59Arg
M0051234 EEDJCAEJ_00018 17554 5 Skin 0.08 protein_coding missense_variant MODERATE 29G>A Gly10Glu
M0051235 EEDJCAEJ_00008 8273 11 Skin 0.17 protein_coding synonymous_variant LOW 117C>A Ala39Ala
M0051236 EEDJCAEJ_00009 14443 8 Skin 0.13 protein_coding upstream_gene_variant MODIFIER -4834A>G None
M0051237 EEDJCAEJ_00017 15186 3 Skin 0.05 protein_coding synonymous_variant LOW 30G>A Leu10Leu
M0051238 EEDJCAEJ_00007 5365 4 Skin 0.06 protein_coding missense_variant MODERATE 1174G>A Val392Ile
M0051239 EEDJCAEJ_00004 3003 3 Skin 0.05 protein_coding missense_variant MODERATE 347A>G Glu116Gly
M0051240 EEDJCAEJ_00014 14047 5 Skin 0.08 protein_coding synonymous_variant LOW 132G>A Ser44Ser
M0051241 EEDJCAEJ_00013 11383 3 Skin 0.05 protein_coding missense_variant MODERATE 145G>A Gly49Ser
M0051242 EEDJCAEJ_00004 3341 3 Skin 0.05 protein_coding synonymous_variant LOW 9G>A Thr3Thr
M0051243 EEDJCAEJ_00004 3344 3 Skin 0.05 protein_coding synonymous_variant LOW 6G>T Pro2Pro
M0051244 EEDJCAEJ_00003 3363 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -597A>G None
M0051245 EEDJCAEJ_00003 3367 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -601C>G None
M0051246 EEDJCAEJ_00003 3402 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -636C>A None
M0051247 EEDJCAEJ_00003 3410 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -644T>A None
M0051248 EEDJCAEJ_00003 3436 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -670C>T None
M0051249 EEDJCAEJ_00003 3458 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -692G>A None
M0051250 EEDJCAEJ_00003 3462 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -696G>A None
M0051251 EEDJCAEJ_00003 3482 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -716C>T None
M0051252 EEDJCAEJ_00003 3494 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -728T>G None
M0051253 EEDJCAEJ_00003 3535 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -769C>T None
M0051254 EEDJCAEJ_00003 3542 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -776C>T None
M0051255 EEDJCAEJ_00003 3559 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -793G>A None
M0051256 EEDJCAEJ_00003 3564 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -798G>A None
M0051257 EEDJCAEJ_00003 3565 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -799G>A None
M0051258 EEDJCAEJ_00003 3585 3 Skin 0.05 protein_coding upstream_gene_variant MODIFIER -819T>C None
M0051259 EEDJCAEJ_00003 2521 3 Skin 0.05 protein_coding synonymous_variant LOW 246C>T Arg82Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage
EEDJCAEJ_00002 AEW82962.1|CE4 100 6.51e-229 1 356 1 1
EEDJCAEJ_00014 AFU40163.1|PL8 100 0 1 826 1 1
EEDJCAEJ_00017 BCB10236.1|GH154 100 2.86e-242 1 317 1 1





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term