Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2654
  Reference Plasmid   1111525849858958_bin.4__k141_221982
  Reference Plasmid Size   2350
  Reference Plasmid GC Content   0.69
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051260 CJEBGGGC_00001 293 3 Skin 0.60 protein_coding missense_variant MODERATE 1578A>T Gln526His
M0051261 CJEBGGGC_00001 845 3 Skin 0.60 protein_coding synonymous_variant LOW 1026C>T Arg342Arg
M0051262 CJEBGGGC_00001 971 4 Skin 0.80 protein_coding synonymous_variant LOW 900T>C Ala300Ala
M0051263 CJEBGGGC_00001 974 4 Skin 0.80 protein_coding synonymous_variant LOW 897T>G Pro299Pro
M0051264 CJEBGGGC_00001 977 4 Skin 0.80 protein_coding synonymous_variant LOW 894T>C His298His
M0051265 CJEBGGGC_00001 983 4 Skin 0.80 protein_coding synonymous_variant LOW 888T>C Gly296Gly
M0051266 CJEBGGGC_00001 1015 4 Skin 0.80 protein_coding missense_variant MODERATE 856A>G Met286Val
M0051267 CJEBGGGC_00001 1022 3 Skin 0.60 protein_coding missense_variant MODERATE 849C>G Asn283Lys
M0051268 CJEBGGGC_00001 1023 3 Skin 0.60 protein_coding missense_variant MODERATE 848A>C Asn283Thr
M0051269 CJEBGGGC_00001 1024 3 Skin 0.60 protein_coding missense_variant MODERATE 847A>G Asn283Asp
M0051270 CJEBGGGC_00001 1025 3 Skin 0.60 protein_coding synonymous_variant LOW 846C>T Ala282Ala
M0051271 CJEBGGGC_00001 1027 3 Skin 0.60 protein_coding missense_variant MODERATE 844G>A Ala282Thr
M0051272 CJEBGGGC_00001 1028 3 Skin 0.60 protein_coding synonymous_variant LOW 843A>G Gln281Gln
M0051273 CJEBGGGC_00001 1041 4 Skin 0.80 protein_coding missense_variant MODERATE 830A>C Asn277Thr
M0051274 CJEBGGGC_00001 1715 3 Skin 0.60 protein_coding synonymous_variant LOW 156G>C Arg52Arg






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term