Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2656
  Reference Plasmid   1111525849858985_bin.22__k141_5037
  Reference Plasmid Size   3371
  Reference Plasmid GC Content   0.31
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051391 JJMCAOAC_00002 170 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1509G>T None
M0051392 JJMCAOAC_00002 306 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -1373G>T None
M0051393 JJMCAOAC_00002 307 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1372T>C None
M0051394 JJMCAOAC_00002 378 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -1301G>A None
M0051395 JJMCAOAC_00002 461 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -1218A>T None
M0051396 JJMCAOAC_00001 588 4 Skin 0.67 protein_coding missense_variant MODERATE 936T>A Asn312Lys
M0051397 JJMCAOAC_00001 599 4 Skin 0.67 protein_coding missense_variant MODERATE 925T>C Ser309Pro
M0051398 JJMCAOAC_00001 825 4 Skin 0.67 protein_coding synonymous_variant LOW 699G>A Gln233Gln
M0051399 JJMCAOAC_00001 939 3 Skin 0.50 protein_coding synonymous_variant LOW 585A>T Ala195Ala
M0051400 JJMCAOAC_00001 1213 4 Skin 0.67 protein_coding missense_variant MODERATE 311A>T Tyr104Phe
M0051401 JJMCAOAC_00001 1243 5 Skin 0.83 protein_coding missense_variant MODERATE 281A>G Glu94Gly
M0051402 JJMCAOAC_00001 1263 5 Skin 0.83 protein_coding synonymous_variant LOW 261G>A Ser87Ser
M0051403 JJMCAOAC_00001 1332 3 Skin 0.50 protein_coding synonymous_variant LOW 192T>C Ser64Ser
M0051404 JJMCAOAC_00001 1341 4 Skin 0.67 protein_coding synonymous_variant LOW 183T>C Pro61Pro
M0051405 JJMCAOAC_00001 1350 3 Skin 0.50 protein_coding synonymous_variant LOW 174C>T Ile58Ile
M0051406 JJMCAOAC_00001 1398 5 Skin 0.83 protein_coding synonymous_variant LOW 126T>A Val42Val
M0051407 JJMCAOAC_00001 1410 5 Skin 0.83 protein_coding synonymous_variant LOW 114C>T Gly38Gly
M0051408 JJMCAOAC_00001 1568 5 Skin 0.83 protein_coding upstream_gene_variant MODIFIER -45G>T None
M0051409 JJMCAOAC_00002 1801 5 Skin 0.83 protein_coding synonymous_variant LOW 123A>C Arg41Arg
M0051410 JJMCAOAC_00002 1843 3 Skin 0.50 protein_coding synonymous_variant LOW 165G>A Gln55Gln
M0051411 JJMCAOAC_00002 1864 4 Skin 0.67 protein_coding synonymous_variant LOW 186C>T Tyr62Tyr
M0051412 JJMCAOAC_00002 1959 4 Skin 0.67 protein_coding missense_variant MODERATE 281C>A Ala94Asp
M0051413 JJMCAOAC_00002 2054 6 Skin 1.00 protein_coding missense_variant MODERATE 376G>A Asp126Asn
M0051414 JJMCAOAC_00001 2175 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -652T>C None
M0051415 JJMCAOAC_00001 2225 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -702G>A None
M0051416 JJMCAOAC_00001 2255 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -732C>A None
M0051417 JJMCAOAC_00001 2290 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -767C>T None
M0051418 JJMCAOAC_00001 2304 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -781C>A None
M0051419 JJMCAOAC_00001 2333 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -810C>T None
M0051420 JJMCAOAC_00001 2373 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -850C>T None
M0051421 JJMCAOAC_00001 2399 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -876T>G None
M0051422 JJMCAOAC_00001 2402 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -879A>G None
M0051423 JJMCAOAC_00001 2405 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -882A>T None
M0051424 JJMCAOAC_00001 2421 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -898C>T None
M0051425 JJMCAOAC_00001 2435 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -912T>C None
M0051426 JJMCAOAC_00001 2440 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -917T>C None
M0051427 JJMCAOAC_00001 2468 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -945T>G None
M0051428 JJMCAOAC_00001 2504 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -981T>C None
M0051429 JJMCAOAC_00001 2558 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1035A>T None
M0051430 JJMCAOAC_00002 529 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -1150A>G None
M0051431 JJMCAOAC_00001 633 3 Skin 0.50 protein_coding synonymous_variant LOW 891A>G Ser297Ser
M0051432 JJMCAOAC_00001 696 3 Skin 0.50 protein_coding synonymous_variant LOW 828T>C Ile276Ile
M0051433 JJMCAOAC_00001 1104 3 Skin 0.50 protein_coding synonymous_variant LOW 420C>G Ala140Ala
M0051434 JJMCAOAC_00001 1107 3 Skin 0.50 protein_coding synonymous_variant LOW 417A>G Val139Val
M0051435 JJMCAOAC_00001 1446 3 Skin 0.50 protein_coding synonymous_variant LOW 78C>T Gly26Gly
M0051436 JJMCAOAC_00001 1485 3 Skin 0.50 protein_coding synonymous_variant LOW 39C>T Asn13Asn
M0051437 JJMCAOAC_00001 1492 3 Skin 0.50 protein_coding missense_variant MODERATE 32G>A Ser11Asn
M0051438 JJMCAOAC_00001 1493 3 Skin 0.50 protein_coding missense_variant MODERATE 31A>G Ser11Gly
M0051439 JJMCAOAC_00001 1507 3 Skin 0.50 protein_coding missense_variant MODERATE 17A>G Gln6Arg
M0051440 JJMCAOAC_00001 1515 3 Skin 0.50 protein_coding missense_variant MODERATE 9T>A Asn3Lys
M0051441 JJMCAOAC_00001 1546 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -23A>T None
M0051442 JJMCAOAC_00001 1562 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -39G>T None
M0051443 JJMCAOAC_00001 1572 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -49A>G None
M0051444 JJMCAOAC_00001 1573 3 Skin 0.50 protein_coding upstream_gene_variant MODIFIER -50C>T None
M0051445 JJMCAOAC_00001 1595 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -72T>A None
M0051446 JJMCAOAC_00001 1598 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -75G>A None
M0051447 JJMCAOAC_00001 1608 4 Skin 0.67 protein_coding upstream_gene_variant MODIFIER -85T>C None
M0051448 JJMCAOAC_00002 1712 3 Skin 0.50 protein_coding synonymous_variant LOW 34T>C Leu12Leu
M0051449 JJMCAOAC_00002 2038 3 Skin 0.50 protein_coding synonymous_variant LOW 360A>T Ile120Ile






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term