Annotation Categories of the Plasmid Cluster







Summary of the plasmid cluster

Basic Information about the Plasmid Cluster

  Cluster Information   Plasmid Cluster ID   C2657
  Reference Plasmid   1111525849858985_bin.8__k141_134649
  Reference Plasmid Size   10334
  Reference Plasmid GC Content   0.36
  Reference Plasmid Mobility Type   non-mobilizable





Mutation sites in the plasmid cluster


The table lists mutations identified in the plasmid cluster.
Note: Mutations identified in this plasmid cluster are listed below. Click on a mutation ID to view full details..

mutid gname pos count tissue frequnt biotype consequence impact nucchange aachange
M0051450 DDLCAMPN_00001 454 5 Skin 0.56 protein_coding stop_lost&splice_region_variant HIGH 184T>C Ter62Argext*?
M0051451 DDLCAMPN_00001 593 5 Skin 0.56 protein_coding synonymous_variant LOW 45T>C His15His
M0051452 DDLCAMPN_00002 806 5 Skin 0.56 protein_coding synonymous_variant LOW 339C>T Gly113Gly
M0051453 DDLCAMPN_00002 820 5 Skin 0.56 protein_coding missense_variant MODERATE 325G>A Asp109Asn
M0051454 DDLCAMPN_00002 821 5 Skin 0.56 protein_coding synonymous_variant LOW 324G>A Thr108Thr
M0051455 DDLCAMPN_00002 844 5 Skin 0.56 protein_coding missense_variant MODERATE 301C>A Gln101Lys
M0051456 DDLCAMPN_00002 848 5 Skin 0.56 protein_coding synonymous_variant LOW 297T>C Ser99Ser
M0051457 DDLCAMPN_00002 857 5 Skin 0.56 protein_coding synonymous_variant LOW 288A>G Arg96Arg
M0051458 DDLCAMPN_00002 858 5 Skin 0.56 protein_coding missense_variant MODERATE 287G>T Arg96Leu
M0051459 DDLCAMPN_00002 886 5 Skin 0.56 protein_coding missense_variant MODERATE 259A>G Ile87Val
M0051460 DDLCAMPN_00002 887 5 Skin 0.56 protein_coding missense_variant MODERATE 258T>A Asp86Glu
M0051461 DDLCAMPN_00002 893 5 Skin 0.56 protein_coding missense_variant MODERATE 252G>C Lys84Asn
M0051462 DDLCAMPN_00002 894 5 Skin 0.56 protein_coding missense_variant MODERATE 251A>C Lys84Thr
M0051463 DDLCAMPN_00002 913 5 Skin 0.56 protein_coding synonymous_variant LOW 232C>T Leu78Leu
M0051464 DDLCAMPN_00002 939 5 Skin 0.56 protein_coding missense_variant MODERATE 206G>A Arg69Lys
M0051465 DDLCAMPN_00002 959 5 Skin 0.56 protein_coding synonymous_variant LOW 186C>T Asp62Asp
M0051466 DDLCAMPN_00002 974 5 Skin 0.56 protein_coding synonymous_variant LOW 171T>A Ile57Ile
M0051467 DDLCAMPN_00002 992 5 Skin 0.56 protein_coding synonymous_variant LOW 153C>T Ala51Ala
M0051468 DDLCAMPN_00003 1396 5 Skin 0.56 protein_coding missense_variant MODERATE 538G>A Glu180Lys
M0051469 DDLCAMPN_00003 1613 5 Skin 0.56 protein_coding synonymous_variant LOW 321C>T Asn107Asn
M0051470 DDLCAMPN_00003 1631 5 Skin 0.56 protein_coding synonymous_variant LOW 303A>C Thr101Thr
M0051471 DDLCAMPN_00003 1758 5 Skin 0.56 protein_coding missense_variant MODERATE 176A>C Asn59Thr
M0051472 DDLCAMPN_00003 1763 5 Skin 0.56 protein_coding missense_variant MODERATE 171A>G Ile57Met
M0051473 DDLCAMPN_00003 1776 5 Skin 0.56 protein_coding missense_variant MODERATE 158G>A Arg53His
M0051474 DDLCAMPN_00003 1786 5 Skin 0.56 protein_coding missense_variant MODERATE 148A>T Met50Leu
M0051475 DDLCAMPN_00003 1811 5 Skin 0.56 protein_coding synonymous_variant LOW 123A>G Leu41Leu
M0051476 DDLCAMPN_00004 2106 5 Skin 0.56 protein_coding synonymous_variant LOW 528C>T Ser176Ser
M0051477 DDLCAMPN_00004 2230 5 Skin 0.56 protein_coding missense_variant MODERATE 404T>C Met135Thr
M0051478 DDLCAMPN_00004 2577 5 Skin 0.56 protein_coding synonymous_variant LOW 57C>T Ser19Ser
M0051479 DDLCAMPN_00004 2601 5 Skin 0.56 protein_coding synonymous_variant LOW 33C>T Pro11Pro
M0051480 DDLCAMPN_00001 3853 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3216T>A None
M0051481 DDLCAMPN_00001 4227 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3590G>T None
M0051482 DDLCAMPN_00001 4453 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3816A>G None
M0051483 DDLCAMPN_00001 4500 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3863A>C None
M0051484 DDLCAMPN_00001 4523 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3886C>T None
M0051485 DDLCAMPN_00001 4560 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3923T>C None
M0051486 DDLCAMPN_00001 4575 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -3938C>T None
M0051487 DDLCAMPN_00001 4663 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -4026C>A None
M0051488 DDLCAMPN_00001 4664 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -4027G>C None
M0051489 DDLCAMPN_00001 4700 5 Skin 0.56 protein_coding upstream_gene_variant MODIFIER -4063T>C None






Analysis of virulence factors contributing to bacterial pathogenicity


This table presents virulence factors identified within the plasmid cluster.
      Note: Virulence factor analysis was performed using VFDB. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known virulence factors are listed.

Gene Name vf_gene_id vf_name identity evalue qstart qend query_coverage subject_coverage vf_category gene_description condition







        Analysis of biocide and heavy metal resistance genes to assess antimicrobial risk and environmental impact


This table presents biocides and heavy metals resistance genes identified within the plasmid cluster.
      Note: Analyzing biocide and heavy metal resistance genes based on BacMet to evaluate bacterial resistance risk and the potential impact of environmental heavy metal contamination. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, E-value < 1e-5) to known biocide and heavy metal resistance genes are listed.

Gene Name compound identity evalue qstart qend query_coverage subject_coverage group






        Analyzing antimicrobial resistance genes to assess bacterial resistance to antibiotics and other antimicrobial agents


This table presents antimicrobial resistance genes identified within the plasmid cluster.
      Note: Antimicrobial resistance was performed using CARD. Genes in plasmid clusters showing strong homology (identity > 70%, coverage > 70%, E-value < 1e-5) to known antimicrobial resistance genes are listed.

Gene Name aro_accession identity evalue qstart qend query_coverage subject_coverage drug_class amr_gene_family resistance_mechanism






Analysis of pathogenicity genes to explore pathogen-host interactions


This table presents host pathogen-host interactions within the plasmid cluster.
      Note: Analyzing pathogenicity-related genes using PHI-base to understand pathogen virulence mechanisms and their impact on host interactions. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e-5) to known pathogenicity-related genes are listed.

Gene Name phi_molconn_id host gene_name identity evalue qstart qend query_coverage subject_coverage host_descripton disease_name function phenotype_of_mutant






        Analyzing carbohydrate-active enzyme genes to uncover mechanisms of nutrient degradation


This table presents carbohydrate-active enzyme genes identified within the plasmid cluster.
      Note: Annotation of carbohydrate-active enzyme genes was performed using CAZy to explore mechanisms of nutrient breakdown and utilization. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known CAZyme genes are listed.

Gene Name cazy_id identity evalue qstart qend query_coverage subject_coverage





        Analyzing transport proteins to understand bacterial strategies for substrate uptake and detoxification


This table presents transport proteins within the plasmid cluster.
      Note: Investigation of transport proteins based on TCDB to uncover bacterial mechanisms of substrate transport and environmental detoxification. Genes in plasmid clusters showing strong homology (identity > 70%, subject coverage > 70%, and E-value < 1e−5) to known transport protein entries are listed.

Gene Name tcid identity evalue qstart qend query_coverage subject_coverage class_field class_term subclass subclass_term family family_term